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Shop By Category | Detergents & Membrane Agents

Detergents & Membrane Agents
Surfactants play a vital role in molecular biology techniques, allowing researchers the ability to lyse cells or solubilize membrane proteins. GoldBio provides high quality ionic, nonionic and zwitterionic detergents that are ideal for a variety research methods but at a fraction of the price of other commercially available detergents. GoldBio’s selection includes CHAPS, DDM, BRIJ-35, octylthiogalactoside and octylglucoside among others, many of which are nondenaturing.
Displaying 1-18 of 18 results.
1,2-Diarachidoyl-sn-glycerol
Catalog ID
Size
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1,2-Diarachidoyl-sn-glycerol product image
D-132-100
100 mg
$ 138.00
Description
Product Specifications1,2-Diarachidoyl-sn-glycerol; L-1,2-Diarachidoylglycerol; 1,2-Dieicosanoyl-sn-glycerolFormula: C43H84O5MW: 681.12 g/molStorage/Handling: Store at -20°C.PubChem Chemical ID:15151388 View product page →
Specifications
CAS Number 147514-21-4
Technical Resources

No resources are available for this product.

1,2-Dimyristoyl-rac-glycerol
Catalog ID
Size
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1,2-Dimyristoyl-rac-glycerol product image
D-515-2.5
2.5 g
$ 221.00
D-515-5
5 g
$ 380.00
D-515-10
10 g
$ 655.00
D-515-25
25 g
$ 1411.00
Description
1,2-Dimyristoyl-rac-glycerol is a carboxylic ester, glycerolipid and diglyceride with an attached myristoyl group, promoting interactions between proteins and lipids. It can be employed as a detergent or reagent. It’s functional in cell biology experimentation concerning metabolism and metabolic pathways involving glycerolipids. As a diglyceride, the substance consists of two fatty acid chains covalently bonded to the glycerol molecule in the 1,2- formation. Diglyceride (DAG) research investigates the process of suppressing fat accumulation through DAG consumption. Product Specifications 1,2-Dimyristoyl-rac-glycerol 1,2-Ditetradecoyl-rac-glycerol 1,2-Dimyristin Dl-alpha,beta-DimyristinFormula: C31H60O5 MW: 512.81 g/mol Storage/Handling: Store at room temperature. PubChem Chemical ID: 89298 View product page →
Specifications
CAS Number 20255-94-1
Technical Resources

No resources are available for this product.

1,2-Dipalmitoyl-rac-glycero-3-phosphocholine
Catalog ID
Size
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1,2-Dipalmitoyl-rac-glycero-3-phosphocholine product image
D-226-500
0.5 g
$ 155.00
D-226-1
1 g
$ 290.00
D-226-2.5
2.5 g
$ 677.00
D-226-5
5 g
$ 1265.00
Description
1,2-Dipalmitoyl-rac-glycero-3-phosphocholine is a phospholipid with two palmitic acids and is the racemic mixture of Dipalmitoylphosphatidylcholine (also known as Colfosceril palmitate or DPPC). The phosphocholine head is sensitive to electric charges at the membrane surface when bound to pure phospholipids. When added to a solution containing charged ions, this sensitivity can shift the nitrogen cation away from a lack of positive charge or towards a positive charge in solution. In a research environment, it is useful in studying changes of biological membranes and liposomes. Because of its ability to form simple phospholipid bilayers, it is useful in computer modeling of bilayers View product page →
Specifications
CAS Number 2644-64-6
Technical Resources
Bactenecin
Catalog ID
Size
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Bactenecin product image
B-305-500
500 µg
$ 400.00
B-305-1
1 mg
$ 675.00
Description
Bactenecin is a twelve residue antimicrobial peptide that is recognized by its disulfide linked cyclical structure. It lyses gram-negative bacteria by increasing permeability through binding lipopolysaccharides (LPS). The bactenecin/LPS conjugate forms a β-hairpin structures which integrate with the bacterial membrane, forming pores. Cytosol contents leak with pore formation and lysis occurs with higher bactenecin concentrationsAntibiotics are often used in clinical in vitro tests known as antimicrobial susceptibility tests or ASTs to determine their efficacy against certain bacterial species. They are tested against gram-negative and gram-positive bacteria using panels, discs, and MIC strips by medical microbiologists. ASTs decrease the risk of View product page →
Specifications
CAS Number 116229-36-8
Technical Resources

No resources are available for this product.

BRIJ-35
Catalog ID
Size
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BRIJ-35 product image
B-060-250
250 g
$ 15.00
B-060-500
500 g
$ 28.00
B-060-1
1 kg
$ 42.00
Description
BRIJ-35 is a nonionic surfactant/solubilizer that is a long chain polyoxyethylene glycol alkyl ether which has multiple applications in various fields. BRIJ-35 is used as an analytical tool for surfactant analysis in high-pressure liquid chromatography (HPLC) and can be used to remove detergents from protein samples via Ion-Exchange Chromatography. Another use for BRIJ-35 is as an oil dispersant, helping subdivide large spills into smaller droplets for easier breakdown. Most commonly, BRIJ-35 is used in buffers for lysing cells and disassociating cell membrane complexes due to its efficacy as a dispersant. It quickly and gently solubilizes membranes for the purpose of analysis, while View product page →
Specifications
CAS Number 9002-92-0
Technical Resources
Cetylpyridinium chloride
Catalog ID
Size
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Cetylpyridinium chloride product image
C-120-25
25 g
$ 26.25
Description
Cetylpyridinium chloride is a cationic quaternary ammonium compound that has been used to eliminate oral pathogens. It has shown a high degree of efficacy towards gram-positive, gram-negative bacteria and some pathogenic fungi.Cetylpyridinium chloride functions as a surfactant, reducing the surface tension between pathogenic membranes and their environments. Greater interaction between the membrane and environment disrupts the cell membrane and osmoregulation. Compromising the membrane ultimately results in cell death.Product SpecificationsCetylpyridinium chlorideN-Hexadecylpyridinium chloride monohydrateFormula: C21H38ClN ∙ H2O MW: 358.00 g/molStorage/Handling: View product page →
Specifications
CAS Number 6004-24-6
Technical Resources

No resources are available for this product.

CHAPS
Catalog ID
Size
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CHAPS product image
C-080-1
1 g
$ 20.00
C-080-5
5 g
$ 43.00
C-080-10
10 g
$ 54.00
C-080-25
25 g
$ 108.00
C-080-100
100 g
$ 276.00
C-080-250
250 g
$ 554.00
C-080-500
500 g
$ 995.00
Description

CHAPS, also known as ((3-cholamidopropyl)dimethylammonio)-1-propanesulfonate, is a zwitterionic surfactant primarily used to solubilize membrane proteins and other macromolecules.

Oftentimes, mild detergents are used in cell lysis applications by interfering with membrane interactions.

View product page →
Specifications
CAS Number 75621-03-3
Technical Resources
Deoxycholic Acid Sodium Salt
Catalog ID
Size
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Deoxycholic Acid Sodium Salt product image
D-070-25
25 g
$ 25.00
D-070-100
100 g
$ 65.00
D-070-500
500 g
$ 270.00
Description
Deoxycholic acid (typically abbreviated DOC) is a bile acid typically found in the intestine. Bile acids typically cause DNA damage and can lead to an increase in mutations. Deoxycholic acid can be covalently attached to glycol chitosan as a delivery system in nanotechnological applications. Many other applications, such as those to perform 1,4-addition of diethylzinc to acyclic enones, requires the binding of Deoxycholic acid to other molecules to create ligands that are conducive to addition of metals to certain enones. In more general applications, Deoxycholic acid is used to increase the solubilization of cells. Deoxycholic acid is typically used as an View product page →
Specifications
CAS Number 302-95-4
Technical Resources
Digitonin Special Grade (water soluble)
Catalog ID
Size
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Digitonin Special Grade (water soluble) product image
D-180-250
250 mg
$ 92.00
D-180-1
1 g
$ 339.00
D-180-2.5
2.5 g
$ 688.00
D-180-5
5 g
$ 1327.00
D-180-10
10 g
$ 2149.00
Description

View product page →
Specifications
CAS Number 11024-24-1
Technical Resources
Glycochenodeoxycholic acid
Catalog ID
Size
Pricing
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Glycochenodeoxycholic acid product image
G-540-25
25 g
$ 293.00
G-540-50
50 g
$ 526.00
G-540-100
100 g
$ 943.00
G-540-250
250 g
$ 2108.00
Description
Glycochenodeoxycholic acid (GCDC) is a bile salt that is used as an anionic detergent to solubilize lipids. In other applications GCDC can be used to induce hepatocyte apoptosis and inhibit calcium phosphate precipitation in vitro. GCDC is also used in applications analyzing the damage done to DNA by other bile acids. Product Specifications Glycochenodeoxycholic acid Formula:C26H42NNaO5 MW:471.61 g/mol Storage/Handling:Store at 5°C. PubChem Chemical ID:23675209 View product page →
Specifications
CAS Number 640-79-9
Technical Resources

No resources are available for this product.

Glycochenodeoxycholic acid, sodium salt
Catalog ID
Size
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Glycochenodeoxycholic acid, sodium salt  product image
G-590-5
5 g
$ 187.00
G-590-10
10 g
$ 357.00
G-590-25
25 g
$ 847.00
G-590-50
50 g
$ 1610.00
Description
Glycochenodeoxycholic acid (GCDC) is a bile salt that is used as an anionic detergent to solubilize lipids. In other applications GCDC can be used to induce hepatocyte apoptosis and inhibit calcium phosphate precipitation in vitro. GCDC is also used in applications analyzing the damage done to DNA by other bile acids. Product SpecificationsGlycochenodeoxycholic acid, sodium salt;Sodium glycochenodeoxycholateFormula: C26H42NNaO5 MW: 471.61 g/mol Storage/Handling: Store at 4°C. PubChem Chemical ID: 23675209 View product page →
Specifications
CAS Number 16564-43-5
Technical Resources
Hexanoyl-DL-carnitine chloride
Catalog ID
Size
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Hexanoyl-DL-carnitine chloride product image
H-990-50
50 mg
$ 128.00
H-990-100
100 mg
$ 176.00
H-990-250
250 mg
$ 304.00
H-990-500
500 mg
$ 419.00
Description
Hexanoyl-DL-carnitine chloride is a fatty acylcarnitine with a hexanoyl group, biologically active in intermediate lipid metabolism in cells. It’s employed as a detergent, surfactant and reagent. Studies conducted with acylcarnitines and dietary l-carnitine amino acid derivatives have shown that mutated coding for carnitine-acylcarnitine translocase causes inborn lipid metabolism disorders. Analyzing acylcarnitine production can explain the poor absorption of l-cartinine, and this can be quantified by HPLC. HPLC also provides a profile of the alcylcarnitine chains present. Product Specifications Hexanoyl-DL-carnitine chloride Caproyl-DL-carnitine hydrochloride(±)-Hexanoylcarnitine chloride Formula: C13H26ClNO4 MW: 295.80 g/mol Storage/Handling: View product page →
Specifications
CAS Number 6920-35-0
Technical Resources

No resources are available for this product.

n-Dodecyl-B-D-maltoside (DDM)
Catalog ID
Size
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n-Dodecyl-B-D-maltoside (DDM) product image
DDM5
5 g
$ 304.00
DDM25
25 g
$ 1317.00
DDM50
50 g
$ 2487.00
DDM100
100 g
$ 4480.00
Description
n-Dodecyl-B-D-Maltoside, or DDM, is a maltoside based non-ionic detergent with a hydrophilic maltose head and a hydrophobic long chain alkyl tail. It is considered a gentle detergent that is more efficient than other detergents, such as CHAPS or NP-40. It has a comparatively low critical micelle concentration (CMC) of 0.17mM compared to the other maltoside based detergents.The primary attribute of DDM is its capability to extract hydrophobic proteins while maintaining the solution-phase protein conformation. DDM also allows the protein to be reformed following denaturization. Most membrane-bound proteins are α-helix bundles, which are less robust to changes in their cellular environment. View product page →
Specifications
CAS Number 69227-93-6
Technical Resources
Octylglucoside, Ultra Pure
Catalog ID
Size
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Octylglucoside, Ultra Pure product image
O-110-5
5 g
$ 86.00
O-110-10
10 g
$ 156.00
O-110-25
25 g
$ 345.00
O-110-50
50 g
$ 650.00
Description

Octylglucoside is a nonionic, mild detergent used to isolate membrane proteins in the native state. It can easily be removed during final extractions by dialysis.

Characteristics that contribute to this detergent’s usefulness are its water solubility, chemical structure and small-sized micelles.

Octylglucoside also provides higher resolution of proteins in 2D electrophoresis.

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Specifications
CAS Number 29836-26-8
Technical Resources
Octylthiogalactoside
Catalog ID
Size
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Octylthiogalactoside product image
O-120-5
5 g
$ 220.00
O-120-10
10 g
$ 408.00
O-120-25
25 g
$ 942.00
O-120-50
50 g
$ 1742.00
Description
Octylthiogalactoside is a nonionic detergent and can be used to either inhibit or induce β-galactosidase. It is commonly used to solubilize membrane proteins or lyse cells.  Product Specifications Octylthiogalactoside; Octyl-β-D-thiogalactoside; n-Octyl-1-thio-β-D-Gal; Octyl 1-thiohexopyranoside MOLECULAR BIOLOGY GRADE Formula: C 14H28O5S MW: 308.43 g/mol Storage/Handling:Store at -20°C and protect from light. Forms a colorless, clear solution when dissolved 5% in methanol. PubChem Chemical ID: 24802438 View product page →
Specifications
CAS Number 42891-16-7
Technical Resources
Octylthioglucoside
Catalog ID
Size
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Octylthioglucoside product image
O-130-5
5 g
$ 97.00
O-130-10
10 g
$ 177.00
O-130-25
25 g
$ 299.00
O-130-50
50 g
$ 550.00
Description

Octylthioglucoside is a nonionic detergent that has been used to isolate membrane proteins without inactivation. This product is effective in a variety of protein solubilization and cell lysis processes. And detergents of this nature are ideal when studying the conformation and structure of proteins because the secondary and tertiary structures remain intact.

Compared to octylglucoside, octylthioglycoside is more stable. And it is stable in aqueous solution and easily removed by dialysis. This product is intended for use as a detergent to solubilize membrane-bound proteins in their native state.

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Specifications
CAS Number 85618-21-9
Technical Resources
Palmitoyl-DL-carnitine hydrochloride
Catalog ID
Size
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Palmitoyl-DL-carnitine hydrochloride product image
P-090-2.5
2.5 g
$ 397.00
P-090-5
5 g
$ 662.00
P-090-10
10 g
$ 1103.00
P-090-25
25 g
$ 2296.00
Description
Palmitoyl-DL-carnitine is a long chain fatty acid derivative of carnitine which helps the transfer of long-chain fatty acids across mitochondrial membranes. Because of this characteristic, Palmitoyl-DL-carnitine is useful in helping increase the drug absorption across gastrointestinal cells. Palmitoyl-DL-carnitine also reduces efficacy and increases duration of Ca 2+ dependent events in cells that use calcium signals. When exposed to Carnitine O-palmitoyltransferase, it is reduced to Palmitoyl coenzyme A which is then used in the carnitine shuttle system to transfer acyl-coenzyme A molecules into the mitochondria for β-oxidation. Product SpecificationsPalmitoyl-DL-carnitine Hydrochloride; Hexadecanoyl-DL-carnitine chloride; MOLECULAR BIOLOGY GRADE Formula: C23H46ClNO4 MW: 436.07 g/mol Storage/Handling:Store at -20°C. PubChem Chemical ID: View product page →
Specifications
CAS Number 6865-14-1
Technical Resources

No resources are available for this product.

Tridecyl beta-D-maltopyranoside
Catalog ID
Size
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Tridecyl beta-D-maltopyranoside product image
T-290-1
1 g
$ 333.00
T-290-2.5
2.5 g
$ 756.00
T-290-5
5 g
$ 1373.00
T-290-10
10 g
$ 2496.00
Description
Tridecyl b-D-maltopyranoside is a disaccharide derivative and glycoside which is applied as a non-ionic detergent and surfactant. In studies on membrane protein crystallization, Tridecyl b-D-maltopyranoside proved to be an effective detergent for maintaining protein solubility but necessitates the presence of salt. Tridecyl b-D-maltopyranoside has a longer chain length than Decyl β-D-maltopyranoside, another detergent used on membrane protein crystallization. Decyl β-D-maltopyranoside has been used in micellar electrokinetic chromatography to study enantiomer separation of drugs. Product Specifications Tridecyl b-D-maltopyranoside Tridecyl β-D-maltoside Tridecyl4-O-hexopyranosylhexopyranoside Tridecyl 4-O-α-D-glucopyranosyl-β-D-glucopyranoside Formula: C25H48O11 MW: 524.64 g/mol Storage/Handling: View product page →
Specifications
CAS Number 93911-12-7
Technical Resources

No resources are available for this product.