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Shop By Category Enzymes, Inhibitors & Substrates Enzyme Substrates | Luciferin, Caged Luciferin And Coelenterazine

Luciferin, Caged Luciferin and Coelenterazine
Bioluminescence is the production and emission of light by a living organism. Bioluminescence occurs widely in marine vertebrates and invertebrates, as well as in some fungi, microorganisms and terrestrial invertebrates. Luciferin, the firefly substrate of luciferase, is a common reagent used throughout the biotechnology field. The injection of luciferin allows for the real-time, noninvasive monitoring of disease progression and/or drug efficacy in these model systems through Bioluminescence Imaging (BLI). Coelenterazine is a luminophore is the substrate for many luciferase enzymes, including Renilla reniformis, gaussia, and aequorins. It is commonly used to monitor reporter genes in BRET (Bioluminescence Resonance Energy Transfer), ELISA and HTS methods. Gold Biotechnology’s luciferin and coelenterazine are Proven and Published™ to ensure a quality reagent with optimal potential.
Displaying 1-8 of 8 results.
Coelenterazine
Catalog ID
Size
Pricing
More Info
Coelenterazine product image
CZ2.5
2.5 mg
$ 60.00
CZ5
5 mg
$ 92.00
CZ10
10 mg
$ 141.00
Description

Coelenterazine is a luminophore found in aquatic organisms and is the substrate for many luciferase enzymes, including Renilla reniformis, Gaussia and aequorins. It is commonly used for bioluminescent calcium detection and the monitoring of reporter genes in BRET (Bioluminescence Resonance Energy Transfer), ELISA and HTS methods as well as chemiluminescent detection of superoxide anions and peroxynitrite in cells or tissues.

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Specifications
CAS Number 55779-48-1
Technical Resources
Coelenterazine 400 a
Catalog ID
Size
Pricing
More Info
Coelenterazine 400 a product image
C-320-10
10 mg
$ 278.00
C-320-25
25 mg
$ 579.00
C-320-50
50 mg
$ 963.00
C-320-100
100 mg
$ 1600.00
Description

Coelenterazine 400A is a derivative of coelenterazine and is a good substrate for Renilla reniformis luciferase (RLuc), but does not oxidize well with Gaussia (GLuc). It is the preferred substrate for BRET (Bioluminescence Resonance Energy Transfer) since its emission maximum of 400nm has minimal interference with the GFP emission.

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Specifications
CAS Number 70217-82-2
Technical Resources
D-Luciferin Firefly, free acid (Proven and Published™)
Catalog ID
Size
Pricing
More Info
D-Luciferin Firefly, free acid (Proven and Published™) product image
L-123-250
250 mg
$ 122.00
L-123-500
500 mg
$ 207.00
L-123-1
1 g
$ 276.00
L-123-2.5
2.5 g
$ 649.00
Description

Tested and Certified for in vivo imaging (See "Luciferin FAQ" in additional information)

Luciferin is a common bioluminescent reporter used for in vivo imaging of the expression of luciferase. This water soluble substrate for the firefly luciferase enzyme utilizes ATP and Mg2+ as cofactors to emit a characteristic yellow-green emission in the presence of oxygen, which shifts to red light in vivo at 37°C. Through the utilization of ATP, the reaction can be further used to indicate the presence of energy or life in order to function as a life-death stain.

Luciferin is a common reagent used throughout the biotechnology field and specifically for in vivo imaging. Luciferase labeled tumor cells, stem cells or infectious diseases are often inoculated into research animals such as rats or mice for investigation. The injection of luciferin allows for the real-time, noninvasive monitoring of disease progression and/or drug efficacy in these model systems through Bioluminescence Imaging (BLI).

Luciferin is also commonly used for in vitro research, including luciferase and ATP assays, gene reporter assays, high throughput sequencing and various contamination assays.

Firefly Luciferin is identical to Beetle Luciferin. (See "Additional Information" for structures.)

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Specifications
CAS Number 2591-17-5
Technical Resources
D-Luciferin, Potassium Salt (Proven and Published™)
Catalog ID
Size
Pricing
More Info
D-Luciferin, Potassium Salt (Proven and Published™) product image
LUCK-100
100 mg
$ 52.00
LUCK-250
250 mg
$ 125.00
LUCK-300
300 mg
$ 146.00
LUCK-500
500 mg
$ 188.00
LUCK-1G
1 g
$ 245.00
LUCK-2G
2 x 1 g
$ 472.00
LUCK-3G
3 x 1 g
$ 702.00
LUCK-4G
4 x 1 g
$ 928.00
LUCK-5G
5 x 1 g
$ 1150.00
LUCK-10G
10 x 1 g
$ 2280.00
Description

Luciferin is a common bioluminescent reporter used for in vivo imaging of the expression of luciferase. This water soluble substrate for the firefly luciferase enzyme utilizes ATP and Mg2+ as cofactors to emit a characteristic yellow-green emission in the presence of oxygen, which shifts to red light in vivo at 37°C. Through the utilization of ATP, the reaction can be further used to indicate the presence of energy or life in order to function as a life-death stain.

Luciferin is a common reagent used throughout the biotechnology field and specifically for in vivo imaging. Luciferase labeled tumor cells, stem cells or infectious diseases are often inoculated into research animals such as rats or mice for investigation. The injection of luciferin allows for the real-time, noninvasive monitoring of disease progression and/or drug efficacy in these model systems through Bioluminescence Imaging (BLI).

Luciferin is also commonly used for in vitro research, including luciferase and ATP assays, gene reporter assays, high throughput sequencing and various contamination assays.

Firefly Luciferin is identical to Beetle Luciferin. (See "Additional Information" for structures.)

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Specifications
CAS Number 115144-35-9
Technical Resources
D-Luciferin, Sodium Salt (Proven and Published™)
Catalog ID
Size
Pricing
More Info
D-Luciferin, Sodium Salt (Proven and Published™) product image
LUCNA-100
100 mg
$ 52.00
LUCNA-250
250 mg
$ 125.00
LUCNA-300
300 mg
$ 146.00
LUCNA-500
500 mg
$ 188.00
LUCNA-1G
1 g
$ 245.00
LUCNA-2G
2 x 1 g
$ 472.00
LUCNA-3G
3 x 1 g
$ 702.00
LUCNA-4G
4 x 1 g
$ 928.00
LUCNA-5G
5 x 1 g
$ 1150.00
LUCNA-10G
10 x 1 g
$ 2280.00
Description

Tested and Certified for in vivo imaging (See "Luciferin FAQ" in additional information)

Luciferin is a common bioluminescent reporter used for in vivo imaging of the expression of luciferase. This water soluble substrate for the firefly luciferase enzyme utilizes ATP and Mg2+ as cofactors to emit a characteristic yellow-green emission in the presence of oxygen, which shifts to red light in vivo at 37°C. Through the utilization of ATP, the reaction can be further used to indicate the presence of energy or life in order to function as a life-death stain.

Luciferin is a common reagent used throughout the biotechnology field and specifically for in vivo imaging. Luciferase labeled tumor cells, stem cells or infectious diseases are often inoculated into research animals such as rats or mice for investigation. The injection of luciferin allows for the real-time, noninvasive monitoring of disease progression and/or drug efficacy in these model systems through Bioluminescence Imaging (BLI).

Luciferin is also commonly used for in vitro research, including luciferase and ATP assays, gene reporter assays, high throughput sequencing and various contamination assays.

Firefly Luciferin is identical to Beetle Luciferin. (See "Additional Information" for structures.)

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Specifications
CAS Number 103404-75-7
Technical Resources
DMNPE-caged Luciferin
Catalog ID
Size
Pricing
More Info
DMNPE-caged Luciferin product image
L-130-10
10 mg
$ 67.00
L-130-25
25 mg
$ 153.00
L-130-50
50 mg
$ 279.00
Description

Tested and Certified for in vivo imaging (See "Luciferin FAQ" in additional information)

Luciferin is a common bioluminescent reporter used for in vivo imaging of the expression of the luciferase . This substrate for the firefly luciferase enzyme utilizes ATP and Mg2+ as cofactors and emits a characteristic yellow-green emission in the presence of oxygen, which shifts to red light in vivo at 37°C.

Luciferin is a common reagent used throughout the biotechnology field and specifically for in vivo imaging. Luciferase labeled tumor cells, stem cells or infectious diseases are often inoculated into research animals such as rats or mice for investigation. The injection of luciferin allows for the real-time, noninvasive monitoring of disease progression and/or drug efficacy in these model systems through Bioluminescence Imaging (BLI).

DMNPE-caged luciferin can be used to measure intracellular functions since it readily crosses cell membranes. Once it is inside the cell, active luciferin can be released by UV light or by the action of endogenous intracellular esterases. DMNPE-caged luciferin makes it easier to follow the changes in gene expression in live cells. It can also be used in combination with DMNPE-caged ATP. 

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Specifications
CAS Number 223920-67-0
Technical Resources
DMNPE-caged Luciferin (DL)
Catalog ID
Size
Pricing
More Info
DMNPE-caged Luciferin (DL) product image
L-140-50
50 mg
$ 182.00
Description

Tested and Certified for in vivo imaging (See "Luciferin FAQ" in additional information)

Luciferin is a common bioluminescent reporter used for in vivo imaging of the expression of the luciferase . This substrate for the firefly luciferase enzyme utilizes ATP and Mg2+ as cofactors and emits a characteristic yellow-green emission in the presence of oxygen, which shifts to red light in vivo at 37°C.

Luciferin is a common reagent used throughout the biotechnology field and specifically for in vivo imaging. Luciferase labeled tumor cells, stem cells, or infectious diseases are often inoculated into research animals such as rats or mice for investigation. The injection of luciferin allows for the real-time, noninvasive monitoring of disease progression and/or drug efficacy in these model systems through bioluminescence Imaging (BLI).

DMNPE-caged luciferin can be used to measure intracellular functions since it readily crosses cell membranes. Once it is inside the cell, active luciferin can be released by UV light or by the action of endogenous intracellular esterases. DMNPE-caged luciferin makes it easier to follow the changes in gene expression in live cells. It can also be used in combination with DMNPE-caged ATP.

DL is a racemic mixture of D-Luciferin and L-Luciferin.

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Specifications
CAS Number 154140-55-3
Technical Resources
L-Luciferin, potassium salt
Catalog ID
Size
Pricing
More Info
L-Luciferin, potassium salt product image
L-127-10
10 mg
$ 69.00
L-127-25
25 mg
$ 118.00
L-127-50
50 mg
$ 190.00
Description

Tested and Certified for in vivo imaging (See "Luciferin FAQ" in additional information)

Luciferin is a common bioluminescent reporter used for in vivo imaging of the expression of luciferase. This water soluble substrate for the firefly luciferase enzyme utilizes ATP and Mg2+ as cofactors to emit a characteristic yellow-green emission in the presence of oxygen, which shifts to red light in vivo at 37°C. Through the utilization of ATP, the reaction can be further used to indicate the presence of energy or life in order to function as a life-death stain.

Luciferin is a common reagent used throughout the biotechnology field and specifically for in vivo imaging. Luciferase labeled tumor cells, stem cells or infectious diseases are often inoculated into research animals such as rats or mice for investigation. The injection of Luciferin allows for the real-time, noninvasive monitoring of disease progression and/or drug efficacy in these model systems through Bioluminescence Imaging (BLI).

Luciferin is also commonly used for in vitro research, including luciferase and ATP assays, gene reporter assays, high throughput sequencing and various contamination assays.

L-Luciferin is the chiralic sister to D-luciferin. While most researchers claim that L-luciferin does not produce any light, Lembert has reported that it produces a very weak and extremely slow manifesting light (Lembert, 1996). Nakamura suggested that an enzyme system incorporating luciferase might be responsible for changing the chirality of the L-luciferin to D-luciferin (Nakamura et al., 2006) (See Reference Library).

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Specifications
CAS Number not available
Technical Resources