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Shop By Category Growth Factors | Pdgf & Vegf

PDGF & VEGF
The platelet derived growth factors (PDGF) family consists of five different PDGF isoforms, as well as placental growth factor (PGF) and members of the VEGF subfamily. These proteins all contain a conserved cystine-knot structure that is essential for receptor binding. Both PDGF and VEGF proteins play important roles in angiogenesis and vascularization, as well as in cell proliferation and migration. While members of both the PDGF and VEGF families act as ligands for tyrosine kinase receptors specific to their family, there is some evidence of cross-family receptor binding. GoldBio offers affordable, high quality recombinant proteins from the PDGF and VEGF families.
Displaying 1-6 of 6 results.
PDGFAA (dimer), Rat
Catalog ID
Size
Pricing
More Info
PDGFAA (dimer), Rat product image
1550-14-2
2 μg
$ 66.00
1550-14-10
10 μg
$ 102.00
1550-14-1000
1000 μg
$ 1933.00
Description
GoldBio growth factors are manufactured for RESEARCH USE ONLY and cannot be sold for human consumption! Recombinant Rat Platelet-derived Growth Factor, Alpha Polypeptide (dimer) PDGFA PDGF1 Platelet-derived growth factor (PDGF) is a glycoprotein present in serum but absent from plasma. PDGF has three subforms: PDGFAA, PDGFBB, and PDGF-AB. This form is a disulfide-linked homodimer consisting of two peptide chains A (PDGFAA). It is involved in a number of biological processes, including hyperplasia, embryonic neuron development, chemotaxis, and respiratory tubule epithelial cell development. The function of PDGF is mediated by two tyrosine kinase receptors, PDGFR-α and PDGFR-β. PDGFR-α is the receptor View product page →
Specifications
CAS Number
Technical Resources
PDGFBB (dimer), Human
Catalog ID
Size
Pricing
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PDGFBB (dimer), Human product image
1150-10-2
2 μg
$ 66.00
1150-10-10
10 μg
$ 102.00
1150-10-1000
1000 μg
$ 1933.00
Description
GoldBio growth factors are manufactured for RESEARCH USE ONLY and cannot be sold for human consumption! Recombinant Human Platelet-derived Growth Factor, Beta Polypeptide (dimer) PDGFAB PDGF2 Simian Sarcoma Viral Oncogene Homolog (SSV) Oncogene SIS Becaplermin Platelet-derived growth factor (PDGF) is a glycoprotein present in serum but absent from plasma. PDGF has three subforms: PDGFAA, PDGFBB, and PDGF-AB. This form is a disulfide-linked homodimer consisting of two peptide chains B (PDGFBB). It is involved in a number of biological processes, including hyperplasia, embryonic neuron development, chemotaxis, and respiratory tubule epithelial cell development. In contrast to PDGFAA, the beta chains in PDGFBB are sufficient View product page →
Specifications
CAS Number
Technical Resources
VEGF120, Murine
Catalog ID
Size
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VEGF120, Murine product image
1350-06-2
2 μg
$ 66.00
1350-06-10
10 μg
$ 102.00
1350-06-1000
1000 μg
$ 1933.00
Description
GoldBio growth factors are manufactured for RESEARCH USE ONLY and cannot be sold for human consumption!Recombinant Murine Vascular Endothelial Growth Factor120 VEGF120Vascular Endothelial Growth Factor is a potent growth and angiogenic cytokine. It stimulates proliferation and survival of endothelial cells, and promotes angiogenesis and vascular permeability. VEGF is expressed in vascularized tissues and plays a prominent role in normal and pathological angiogenesis. VEGF has been implicated in the induction of tumor metastasis, intra-ocular neovascular syndromes and angiogenesis. Three mouse cDNA clones (monomeric VEGF having 120, 164 or 188 amino acids) have been identified through alternative splicing. Two receptor View product page →
Specifications
CAS Number
Technical Resources
VEGF164, Rat
Catalog ID
Size
Pricing
More Info
VEGF164, Rat product image
1550-07-2
2 μg
$ 66.00
1550-07-10
10 μg
$ 102.00
1550-07-1000
1000 μg
$ 1933.00
Description
GoldBio growth factors are manufactured for RESEARCH USE ONLY and cannot be sold for human consumption! Recombinant Rat Vascular Endothelial Growth Factor164 VEGF164 Vascular endothelial growth factor is a potent growth factor and angiogenic cytokine. It stimulates proliferation and survival of endothelial cells and promotes angiogenesis and vascular permeability. VEGF is expressed in vascularized tissues and plays a prominent role in normal and pathological angiogenesis. VEGF has been implicated in the induction of tumor metastasis, intra-ocular neovascular syndromes and angiogenesis. Two receptor tyrosine kinases (RTKs), Flt-1 and Flk-1 have been shown to bind VEGF with high affinity. Sterile Filtered White View product page →
Specifications
CAS Number
Technical Resources
VEGF165, Human
Catalog ID
Size
Pricing
More Info
VEGF165, Human product image
1150-05-2
2 μg
$ 66.00
1150-05-10
10 μg
$ 102.00
1150-05-1000
1000 μg
$ 1551.00
Description

GoldBio growth factors are manufactured for RESEARCH USE ONLY and cannot be sold for human consumption! 

VEGF165 is an abundant glycosylated cytokine composed of two identical 165 amino acid chains in the Vascular Endothelial Growth Factor family. It plays a significant role in stimulating angiogenesis, not only during embryonic development, but also upon injury to vascular tissue or when blockage occurs. This growth factor is the most abundant and potent form in its family and uses a heparin-binding mechanism to induce angiogenesis. It has been shown to play a role in tumor metastasis by vascularizing metastatic tissues and to increase capillary permeability. In addition, VEGF165 tightly binds receptor tyrosine kinases Flk-1 and Flt-1. Recent studies implicate VEGF165 in production of osteoclasts in murine bone marrow.

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Specifications
CAS Number
Technical Resources
VEGF165, Murine
Catalog ID
Size
Pricing
More Info
VEGF165, Murine product image
1350-07-2
2 μg
$ 66.00
1350-07-10
10 μg
$ 102.00
1350-07-1000
1000 μg
$ 1933.00
Description
GoldBio growth factors are manufactured for RESEARCH USE ONLY and cannot be sold for human consumption!Recombinant Murine Vascular Endothelial Growth Factor165 VEGF165Vascular Endothelial Growth Factor is a potent growth and angiogenic cytokine. It stimulates proliferation and survival of endothelial cells, and promotes angiogenesis and vascular permeability. VEGF is expressed in vascularized tissues and plays a prominent role in normal and pathological angiogenesis. VEGF has been implicated in the induction of tumor metastasis, intra-ocular neovascular syndromes and angiogenesis. Three mouse cDNA clones (monomeric VEGF having 120, 164 or 188 amino acids) have been identified through alternative splicing. Two receptor View product page →
Specifications
CAS Number
Technical Resources