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Shop By Category | Reducing Agents

Reducing Agents
Reducing Agents, sometimes referred to as reductants or reducers, are elements or compounds that lose an electron to some other chemical species in a redox chemical reaction. A reducing agent is usually in one of its lower oxidation states and is known as the electron donor. Reducing agents are typically used in protein solutions in order to cleave the disulfide bond between cysteine amino acids, but most are used in a variety of other applications across many fields of science. GoldBio has a number of reducing agents available, including DTT (dithiothreitol), glutathione, DTE (dithioerythritol) and TCEP. GoldBio Reducing Agents are Proven and Published™ ensuring quality agents with optimum potential.
Displaying 1-6 of 6 results.
DTE (Dithioerythritol)
Catalog ID
Size
Pricing
More Info
DTE (Dithioerythritol) product image
D-260-25
25 g
$ 123.00
D-260-50
50 g
$ 226.00
D-260-100
100 g
$ 400.00
D-260-250
250 g
$ 925.00
Description
Dithioerythritol (DTE) is one of two Cleland's Reagents (along with DTT). The two chemicals are epimers of each other, in which the hydroxyl groups of DTE are in the cis form as opposed to the trans form for DTT. DTE is a strong reducing agent and is a component of buffers used in protocols for the isolation and purification of proteins. Product Specifications: DTE (Dithioerythritol), Cleland's Reagent; 1,4-Dithioerythritol; erythro-23-dihydroxy-1,4-dithiolbutaneMOLECULAR BIOLOGY GRADEFormula: C4H10O2S2MW: 154.25 g/molStorage/Handling: Store desiccated at -20°C. Protect from light. Solutions should be prepared fresh, daily. Sensitive to air and moisture. Keep under inert gas.PubChem Chemical ID: 439352 View product page →
Specifications
CAS Number 6892-68-8
Technical Resources
DTT (Dithiothreitol) (> 99% pure) Protease free
Catalog ID
Size
Pricing
More Info
DTT (Dithiothreitol) (> 99% pure) Protease free product image
DTT10
10 g
$ 43.00
DTT25
25 g
$ 97.00
DTT50
50 g
$ 173.00
DTT100
100 g
$ 276.00
DTT500
500 g
$ 1236.00
Description

Dithiothreitol (DTT) is the common name of the more popular of the two Cleland’s Reagents (the other being Dithioerythritol or DTE). DTT is a powerful reducing agent that forms a stable six-membered ring with an internal disulfide bond which is resistant to oxidation. DTT is often used for the following: reducing the disulfide bridge of the cross-linker N,N′-bis(acryloyl) cystamine to break apart the matrix of a polyacrylamide gel, the reduction of disulfide bonds in proteins, the prevention of those bonds from forming between cysteine residues and lastly, DTT is often used to reduce thiolated DNA in order to minimize dimerization.

DTT is a nearly 7-fold stronger reduction agent than βME (β-mercaptoethanol) and has a less offensive odor and is less toxic.

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Specifications
CAS Number 27565-41-9 / 3483-12-3
Technical Resources
Glutathione reduced ethyl ester
Catalog ID
Size
Pricing
More Info
G-275-250
0.25 g
$ 198.00
G-275-500
0.5 g
$ 329.00
G-275-1
1 g
$ 549.00
G-275-2.5
2.5 g
$ 1144.00
Description
Product Specifications:  Formula: C 12H21N3O6S MW: 335.38 g/mol Storage/Handling: Store at -20°C. View product page →
Specifications
CAS Number 118421-50-4
Technical Resources

No resources are available for this product.

Glutathione, Oxidized
Catalog ID
Size
Pricing
More Info
Glutathione, Oxidized product image
G-060-1
1 g
$ 52.00
G-060-5
5 g
$ 160.00
G-060-10
10 g
$ 248.00
G-060-25
25 g
$ 498.00
Description

Glutathione, Oxidized (GSSG) is the oxidized version of the naturally occurring and very important detoxification agent glutathione (GSH). When used in vivo, GSSG will not remain oxidized, but rather be reduced back to GSH. A ratio of GSH to GSSG can be used to determine the level of oxidative stress that has occurred in cells. When a cell has higher levels of GSSG, then it can be implied that more oxidative stress has occurred within the cell.

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Specifications
CAS Number 27025-41-8
Technical Resources
L-Glutathione, Reduced
Catalog ID
Size
Pricing
More Info
L-Glutathione, Reduced product image
G-155-25
25 g
$ 72.00
G-155-50
50 g
$ 133.00
G-155-100
100 g
$ 236.00
G-155-250
250 g
$ 411.00
G-155-500
500 g
$ 772.00
G-155-1000
1000 g
$ 1441.00
Description

L-Glutathione is a co-substrate to glutathione transferase found in plants and animals and is involved in the elimination of free radicals resulting from both cellular respiratory and metabolic activities.

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Specifications
CAS Number 70-18-8
Technical Resources
TCEP-HCl
Catalog ID
Size
Pricing
More Info
TCEP-HCl product image
TCEP1
1 g
$ 17.00
TCEP2
2 g
$ 32.00
TCEP5
5 g
$ 64.00
TCEP10
10 g
$ 103.00
TCEP25
25 g
$ 216.00
TCEP50
50 g
$ 402.00
TCEP100
100 g
$ 796.00
Description

TCEP-HCl is an odorless reducing agent suitable for protein applications and in the preparation for electrophoresis. TCEP is water soluble, is stable in a variety of solutions and is particularly useful in the labeling of cysteine residues with maleimides, preventing the cysteines from forming disulfide bonds. As a reducing agent, TCEP has many other desirable features.

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Specifications
CAS Number 51805-45-9
Technical Resources