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Nicotinamide is a metabolized amide form of vitamin B3. It is an anti-cancer agent and inhibitor of PARP-1, which is responsible for repairing DNA damage caused by chemotherapy. Nicotinamide is converted to nicotinamide adenine dinucleotide (NAD) and nicotinamide adenine dinucleotide phosphate (NADP) for use in biological redox reactions. Additionally, nicotinamide is a nicotinamide phosphoribosyltransferase (NAMPT) substrate and anti-inflammatory agent.View product page →
Validamycin is a fungicidal, aminoglycoside antibiotic known to inhibit trehalases in plants, insects, and fungi as well as enhance trehalose accumulation in transgenic plants. It is effective against Pellicularia sasakii and Rhizoctonia solani in plants, but only decreases their virulence instead of exhibiting a fungicidal effect. In addition, validamycin is used to control sheath-blight disease in rice and is most effective against soil-borne pathogens. It is used to study trehalase activity and the synthesis of trehalose.View product page →
Valnemulin is a pleuromutilin antibiotic targeting Mycoplasma bacteria, especially those responsible for bovine respiratory infections. It is freely soluble in aqueous solution.
Valnemulin's mechanism of action involves its inhibition of protein synthesis in bacteria by binding the peptidyl transferase enzyme in the 50s ribosomal subunit.View product page →
Valproate sodium is a branched chain fatty acid with anticancer, neuroprotective, and anti-inflammatory properties. It is also an inhibitor of histone deacetylase (HDAC) through promotion of transcriptionally active chromatin. This inhibition may regulate the neuroprotective effects of valproic acid. The molecules:VEGF, BNDF andGNDF mediate the effects.
While its mechanism is not well understood, it is suggested that valproate sodium inhibits sodium ion channels.View product page →
The vancomycin hydrochloride EZ Pak™ is the fastest and easiest way to make a set amount of sterile vancomycin hydrochloride solution. The kit includes pre-weighed vancomycin hydrochloride powder, a sterile filter, and a sterile container for the filtered solution. No need to calculate, simply add the stated amount of deionized H₂O, filter, and pour into the labeled bottle for easy usage. The EZ Pak™ includes high-quality GoldBio Vancomycin hydrochloride and the sterile solution is ready for tissue culture, bacterial media, or any number of uses.View product page →
Vancomycin hydrochloride is a member of the glycopeptide antibiotic class derived from Streptomyces orientalis. It is effective against gram-positive bacteria and used in studies of antibiotic resistance bacteria and nanoparticle transport studies. Exhibiting low toxicity to plants, vancomycin is suitable for plant selection and prevention of bacterial contamination in plant cell culture applications.View product page →
GoldBio growth factors are manufactured for RESEARCH USE ONLY and cannot be sold for human consumption!
VEGF165 is an abundant glycosylated cytokine composed of two identical 165 amino acid chains in the Vascular Endothelial Growth Factor family. It plays a significant role in stimulating angiogenesis, not only during embryonic development, but also upon injury to vascular tissue or when blockage occurs. This growth factor is the most abundant and potent form in its family and uses a heparin-binding mechanism to induce angiogenesis. It has been shown to play a role in tumor metastasis by vascularizing metastatic tissues and to increase capillary permeability. In addition, VEGF165 tightly binds receptor tyrosine kinases Flk-1 and Flt-1. Recent studies implicate VEGF165 in production of osteoclasts in murine bone marrow.
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A unique combination of a number of proprietary plasmids digested with appropriate restriction enzymes and PCR products to yield 19 fragments, suitable for use as molecular weight standards for agarose gel electrophoresis. The DNA includes fragments ranging from 100-10,000 base pairs. The 500, 1.5K and 3K bands have increased intensity to serve as reference points. The approximate mass of DNA in each band is provided (0.5 μg a load) for approximating the mass of DNA in comparably intense samples of similar size. The ladder is ready-to-use, and is premixed with loading buffer dye for direct loading on gel.View product page →
Vinblastine sulfate is a plant alkaloid anti-mitotic agent and immunosuppressant. It interferes with microtubule assembly by depolymerizing microtubules and arresting the cell cycle. Vinblastine sulfate has been shown to induce apoptosis in a variety of tumor cell lines. It is also a Raf-1 activator and substrate of Pgp and CYP3A4.View product page →
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