Antibiotics & Selection

Antibiotics and Selection tools allow you to selectively control which cells can be found in your cultures.



GoldBio’s broad range of cell selection tools, including hundreds of antibiotics, antifungals and anticancers, plant selection and screening agents allow you to select, control and maintain your cell cultures with confidence and ease, no matter what cells you may be studying.

Showing 1-20 of 275 items.

Magenta-Gal

Catalog ID Size Pricing
B-378-5 5 g $ 219.00
B-378-10 10 g $ 399.00
B-378-25 25 g $ 905.00
B-378-50MG 50 mg $ 23.00

Description

No description available

Product Specifications

Catalog ID B-378
CAS # 93863-88-8
MW 408.63 g/mol
Grade MOLECULAR BIOLOGY GRADE
Storage/Handling Store desiccated at -20°C. Protect from light.
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B-378-5 5 g $ 219.00
B-378-10 10 g $ 399.00
B-378-25 25 g $ 905.00
B-378-50MG 50 mg $ 23.00

Ampicillin (Sodium), USP Grade

Catalog ID Size Pricing
A-301-5 5 g $ 23.00
A-301-10 10 g $ 34.00
A-301-25 25 g $ 46.00
A-301-100 100 g $ 172.00
A-301-500 500 g $ 822.00

Description

Ampicillin sodium is a member of the extended-spectrum β-lactam family and similar in structure to penicillin. It is used in the selection of antibiotic cell hybrids and has a high rate of action against many gram-negative bacterial strains. Ampicillin sodium targets non-ESBL (Extended Spectrum β-lactamase) bacteria including Staphylococcus and Streptococcus species and medically important enteric pathogens such as Shigella and Salmonella. It has been found to be effective against certain β-lactam sensitive VRE or vancomycin resistant Enterococcus species. Resistance to ampicillin is routinely utilized as a selectable marker to confirm successful cell transformation. Ampicillin Sodium is freely soluble in water.

Product Specifications

Catalog ID A-301
CAS # 69-52-3
MW 371.39 g/mol
Storage/Handling Store desiccated at -20°C.
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A-301-5 5 g $ 23.00
A-301-10 10 g $ 34.00
A-301-25 25 g $ 46.00
A-301-100 100 g $ 172.00
A-301-500 500 g $ 822.00

C-390

Catalog ID Size Pricing
C-390-100 100 mg $ 93.00
C-390-25 25 mg $ 34.00
C-390-250 250 mg $ 222.00
C-390-500 500 mg $ 421.00

Description

No description available

Product Specifications

Catalog ID C-390
CAS # 77769-31-4
MW 490.05 g/mol
Grade MOLECULAR BIOLOGY GRADE
Storage/Handling Store at room temperature. Protect from light.
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C-390-100 100 mg $ 93.00
C-390-25 25 mg $ 34.00
C-390-250 250 mg $ 222.00
C-390-500 500 mg $ 421.00

Carbenicillin (Disodium) 100 mg/mL Solution

Catalog ID Size Pricing
C-103-SL10 10 mL $ 46.00
C-103-SL25 25 mL $ 68.00
C-103-SL50 50 mL $ 92.00
C-103-SL100 100 mL $ 115.00

Description

Carbenicillin is a member of the penicillin β-lactam antibiotics. However, unlike most β-lactams, carbenicillin disodium is limited to primarily gram-negative bacteria including Pseudomonas aeruginosa and common enteric species. It can be used in selection protocols and is often preferred over ampicillin due to its increased stability. This allows for less contamination of unwanted bacterial colonies. In addition, carbenicillin has been used to regulate bacterial growth in plants, yielding low regeneration frequencies. It can be used in genetic transformation applications to select for AmpR transformed cells.

GoldBio’s antibiotic solutions are provided ready to use.

Product Specifications

Catalog ID C-103-SL
CAS # 4800-94-6
MW 422.40 g/mol
Grade MOLECULAR BIOLOGY GRADE
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C-103-SL10 10 mL $ 46.00
C-103-SL25 25 mL $ 68.00
C-103-SL50 50 mL $ 92.00
C-103-SL100 100 mL $ 115.00

IPTG

Catalog ID Size Pricing
I2481C 1 g $ 17.00
I2481C5 5 g $ 27.00
I2481C25 25 g $ 115.00
I2481C50 50 g $ 184.00
I2481C100 100 g $ 349.00
I2481C200 200 g $ 675.00
I2481C300 300 g $ 899.00
I2481C500 500 g $ 1,407.00
I2481C400 400 g $ 1,168.00

Description

IPTG is an analog of galactose that is non-metabolizable and inactivates the lac repressor to induce synthesis of β-galactosidase in E. coli. The expression of cloned genes under the control of the lac operon is induced by IPTG. It is also a substrate for thigalactoside transacetylase and has been reported to induce penicillinase in bacteria.

Product Specifications

Catalog ID I2481
CAS # 367-93-1
MW 238.30 g/mol
Grade MOLECULAR BIOLOGY GRADE
Storage/Handling Store desiccated at -20°C. Protect from light.
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I2481C 1 g $ 17.00
I2481C5 5 g $ 27.00
I2481C25 25 g $ 115.00
I2481C50 50 g $ 184.00
I2481C100 100 g $ 349.00
I2481C200 200 g $ 675.00
I2481C300 300 g $ 899.00
I2481C500 500 g $ 1,407.00
I2481C400 400 g $ 1,168.00

X-Gal

Catalog ID Size Pricing
X4281C 1 g $ 42.00
X4281C10 10 g $ 229.00

Description

5-Bromo-4-chloro-3-indolyl β-D-galactopyranoside is most commonly known as X-Gal. X-gal is a histochemical substrate for β-galactosidase which cleaves X-Gal to yield an insoluble blue precipitate.

X-Gal is a mainstay in molecular biology cloning applications in which it is used to detect the activity of β-galactosidase. X-Gal is used to detect the insertion of foreign DNA into the lacZ region of a plasmid DNA. Insertion of DNA into the lacZ region results in the loss of β-galactosidase activity. Bacteria cells that retain active β-galactosidase will result in characteristic blue colonies. Successful disruption of the lacZα gene disrupts the α-complementation of the β-galactosidase gene and the precipitate does not form, resulting in white colonies.

Many other applications also use X-Gal as a substrate to detect β-galactosidase activity. These include β-galactosidase -antibody linked immunoassays and immunohistochemistry, coliphage detection based on β-galactosidase induction and the detection of micrometastasis formation during tumor progession.

Product Specifications

Catalog ID X4281
CAS # 7240-90-6
MW 408.63 g/mol
Grade MOLECULAR BIOLOGY GRADE
Storage/Handling Store at -20°C. Protect from light.
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X4281C 1 g $ 42.00
X4281C10 10 g $ 229.00

Ampicillin (Sodium) 100 mg/mL Solution

Catalog ID Size Pricing
A-301-SL10 10 mL $ 34.00
A-301-SL25 25 mL $ 58.00
A-301-SL50 50 mL $ 81.00
A-301-SL100 100 mL $ 103.00

Description

Ampicillin sodium is a member of the extended-spectrum β-lactam family and similar in structure to penicillin. It is used in the selection of antibiotic cell hybrids and has a high rate of action against many gram-negative bacterial strains. Ampicillin sodium targets non-ESBL (Extended Spectrum β-lactamase) bacteria including Staphylococcus and Streptococcus species and medically important enteric pathogens such as Shigella and Salmonella. It has been found to be effective against certain β-lactam sensitive VRE or vancomycin resistant Enterococcus species. Resistance to ampicillin is routinely utilized as a selectable marker to confirm successful cell transformation. Ampicillin Sodium is freely soluble in water.

GoldBio’s antibiotic solutions are provided ready to use.

Product Specifications

Catalog ID A-301-SL
CAS # 69-52-3
MW 371.40 g/mol
Grade MOLECULAR BIOLOGY GRADE
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A-301-SL10 10 mL $ 34.00
A-301-SL25 25 mL $ 58.00
A-301-SL50 50 mL $ 81.00
A-301-SL100 100 mL $ 103.00

Cefotaxime (Sodium) 100 mg/mL Solution

Catalog ID Size Pricing
C-104-SL10 10 mL $ 46.00
C-104-SL50 50 mL $ 115.00
C-104-SL100 100 mL $ 196.00

Description

Cefotaxime is a third generation, broad-spectrum cephalosporin antibiotic effective against various gram-negative and gram-positive bacteria. However, unlike many other cephalosporins, cefotaxime is not effective against Pseudomonas aeruginosa bacteria. Cefotaxime is often used in Agrobacterium tumefaciens-mediated transformations to regulate bacterial growth. It has been shown to exhibit a synergistic effect with Vancomycin in certain conditions.

GoldBio’s antibiotic solutions are provided ready to use.

Product Specifications

Catalog ID C-104-SL
CAS # 64485-93-4
MW 477.45 g/mol
Grade MOLECULAR BIOLOGY GRADE
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C-104-SL10 10 mL $ 46.00
C-104-SL50 50 mL $ 115.00
C-104-SL100 100 mL $ 196.00

Timentin™ Ticarcillin/Clavulanate (15/1) 100 mg/mL Solution

Catalog ID Size Pricing
T-104-SL100 100 mL $ 161.00
T-104-SL10 10 mL $ 58.00
T-104-SL50 50 mL $ 115.00

Description

Timentin™ is a 15:1 mixture of ticarcillin and clavulanate. Ticarcillin is a penicillin ß-lactam antibiotic, which is susceptible to ß-lactamase degradation. When combined with clavulanate, a ß-lactamase inhibitor, its efficacy is greatly increased. Timentin™ exhibits high activity against gram-negative bacteria and resistant Agrobacterium species.

Product Specifications

Catalog ID T-104-SL
CAS # 4697-14-7; 61177-45-5
MW 665.64 g/mol
Grade MOLECULAR BIOLOGY GRADE
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T-104-SL100 100 mL $ 161.00
T-104-SL10 10 mL $ 58.00
T-104-SL50 50 mL $ 115.00

Spectinomycin Dihydrochloride Pentahydrate 100 mg/mL Solution

Catalog ID Size Pricing
S-140-SL25 25 mL $ 68.00
S-140-SL50 50 mL $ 92.00
S-140-SL100 100 mL $ 115.00
S-140-SL10 10 mL $ 46.00

Description

Spectinomycin is an aminocyclitol antibiotic isolated from Streptomyces spectabilis. It is effective against gram-positive and gram-negative bacteria, but most commonly used against Gonococcus species. It has also been used to monitor cell fate during leaf development and as a selection marker in plants to display successful transformation of the Spcr gene.

Spectinomycin functions by binding the 30s ribosomal subunit, inhibiting tRNA translation and protein synthesis. Resistance to this antibiotic is conferred through the aadA gene and mutated rpsE gene.

GoldBio’s antibiotic solutions are provided ready to use.

Product Specifications

Catalog ID S-140-SL
CAS # 22189-32-8
MW 495.35 g/mol
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S-140-SL25 25 mL $ 68.00
S-140-SL50 50 mL $ 92.00
S-140-SL100 100 mL $ 115.00
S-140-SL10 10 mL $ 46.00

Gentamicin Sulfate 50 mg/mL Solution

Catalog ID Size Pricing
G-400-SL25 25 mL $ 68.00
G-400-SL50 50 mL $ 92.00
G-400-SL100 100 mL $ 115.00
G-400-SL10 10 mL $ 46.00

Description

Gentamicin is a broad-spectrum aminoglycoside antibiotic effective against gram-negative and gram-positive species. In addition, gentamicin exhibits antimicrobial properties against species resistant to tetracycline, colistin, kanamycin, and chloramphenicol.

GoldBio’s antibiotic solutions are provided ready to use.

Product Specifications

Catalog ID G-400-SL
CAS # 1405-41-0
MW 575.67 g/mol
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G-400-SL25 25 mL $ 68.00
G-400-SL50 50 mL $ 92.00
G-400-SL100 100 mL $ 115.00
G-400-SL10 10 mL $ 46.00

Streptomycin Sulfate 100 mg/mL Solution

Catalog ID Size Pricing
S-150-SL10 10 mL $ 34.00
S-150-SL25 25 mL $ 58.00
S-150-SL50 50 mL $ 81.00
S-150-SL100 100 mL $ 115.00

Description

Streptomycin is an aminoglycoside antibiotic primarily effective against gram-negative bacteria and Mycobacterium species. It is commonly used in cell culture media to prevent bacterial contamination. It has also been used to precipitate nucleic acids during protein purification techniques and to study mechanisms of Streptomycin resistance.

GoldBio’s antibiotic solutions are provided ready to use.

Product Specifications

Catalog ID S-150-SL
CAS # 3810-74-0
MW 1457.40 g/mol
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S-150-SL10 10 mL $ 34.00
S-150-SL25 25 mL $ 58.00
S-150-SL50 50 mL $ 81.00
S-150-SL100 100 mL $ 115.00

Kanamycin Monosulfate 50 mg/mL Solution

Catalog ID Size Pricing
K-120-SL25 25 mL $ 46.00
K-120-SL50 50 mL $ 68.00
K-120-SL100 100 mL $ 92.00

Description

Kanamycin is an aminoglycoside antibiotic isolated from Streptomyces kanamyceticus. It is effective against gram-positive and gram-negative bacteria as well as Mycoplasma species. Kanamycin is commonly used to select for bacteria that have been transformed with a kanamycin-resistant gene and plant tissues that have the NPT II (APH3) gene incorporated in them. Kanamycin is very soluble in aqueous solution and is typically used in concentrations of 50-100 µg/ml.

Product Specifications

Catalog ID K-120-SL
CAS # 25389-94-0
MW 582.58 g/mol
Grade MOLECULAR BIOLOGY GRADE
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K-120-SL25 25 mL $ 46.00
K-120-SL50 50 mL $ 68.00
K-120-SL100 100 mL $ 92.00

Nalidixic acid

Catalog ID Size Pricing
N-015-1 1 kg $ 309.00
N-015-100 100 g $ 57.00
N-015-250 250 g $ 86.00
N-015-500 500 g $ 160.00

Description

Nalidixic acid is a naphthyridone antibiotic that is similar in structure and mechanism to quinolones and is effective against both gram-positive and gram-negative bacteria. It acts as a bacteriostatic in lower concentrations but can be bacteriocidal at higher concentrations. Nalidixic acid indirectly inhibits proteins synthesis by binding DNA and interfering with enzymes involved in DNA replication and transcription and is commonly used in the treatment of urinary tract infections.

Product Specifications

Catalog ID N-015
CAS # 389-08-2
MW 232.24 g/mol
Grade MOLECULAR BIOLOGY GRADE
Storage/Handling Store at 4°C.
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N-015-1 1 kg $ 309.00
N-015-100 100 g $ 57.00
N-015-250 250 g $ 86.00
N-015-500 500 g $ 160.00

Erythromycin

Catalog ID Size Pricing
E-350-100 100 g $ 90.00
E-350-250 250 g $ 191.00
E-350-5 5 g $ 24.00
E-350-500 500 g $ 350.00

Description

Erythromycin is a macrolide antibiotic isolated from Streptomyces erythreus. It displays strong efficacy against gram-positive cocci and bacilli and some mycobacteria, mycoplasma, and spirochetes. In addition to its antimicrobial properties, erythromycin is a motilin receptor agonist that has been shown to inhibit respiratory glycoconjugate secretion in vitro. It has also been used to select for recombinant Lactococcus lactis MG1363 strains in microbiological applications.

Product Specifications

Catalog ID E-350
CAS # 114-07-8
MW 733.93 g/mol
Storage/Handling Store at 4°C.
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E-350-100 100 g $ 90.00
E-350-250 250 g $ 191.00
E-350-5 5 g $ 24.00
E-350-500 500 g $ 350.00

Blasticidin S HCl

Catalog ID Size Pricing
B-800-25 25 mg $ 59.00
B-800-100 100 mg $ 187.00
B-800-500 500 mg $ 801.00
B-800-1 1 g $ 1,441.00

Description

Blasticidin S is an aminoacylnucleoside antibiotic isolated from Streptomyces griseochromogenes. It shows high efficacy against both eukaryotic and prokaryotic cells. Aside from its antimicrobial properties, blasticidin has displayed antiviral, antitumor, and antifungal properties and has been used as a selection agent. It has been used to select for cells containing the bls, bsr, or BSD resistance gene as well as HEK293-T cells and HEK-D5 cells. Additionally, blasticidin is effective in preventing cell culture contamination and studying protein synthesis.

Product Specifications

Catalog ID B-800
CAS # 3513-03-9
MW 458.90 g/mol
Storage/Handling Store desiccated at -20°C.
UN Number 2811
Item Class 6.1
Group Number II
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B-800-25 25 mg $ 59.00
B-800-100 100 mg $ 187.00
B-800-500 500 mg $ 801.00
B-800-1 1 g $ 1,441.00

Penicillin G Potassium Salt, USP Grade

There is no image for Penicillin G Potassium Salt, USP Grade Penicillin G Potassium Salt, USP Grade
Catalog ID Size Pricing
P-303-50 50 g $ 37.00
P-303-100 100 g $ 52.00
P-303-1 1 kg $ 317.00

Description

Penicillin G is a β-lactam antibiotic produced by the Penicillium fungus. It has shown efficacy against a variety of Streptococcus species as well as non-penicillinase producing Staphylococcus species. The potassium salt is useful in studying Staphylococcus murosomes and Streptococcus mutans. This product has been tested against both sensitive and resistant cells.

Product Specifications

Catalog ID P-303
CAS # 113-98-4
MW 372.48 g/mol
Grade USP GRADE
Storage/Handling Store desiccated at -20°C.
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P-303-50 50 g $ 37.00
P-303-100 100 g $ 52.00
P-303-1 1 kg $ 317.00

Epibrassinolide

Catalog ID Size Pricing
E-250-10 10 mg $ 52.00
E-250-100 100 mg $ 190.00
E-250-25 25 mg $ 74.00
E-250-50 50 mg $ 111.00

Description

Epibrassinolide is a plant steroid hormone of the brassinosteroid family. Its functions include protection from environmental stressors and altering the metabolism under a variety of conditions. Epibrassinolide has been shown to decrease toxicity and stimulate healthy plant growth in plants under stress.

Product Specifications

Catalog ID E-250
CAS # 78821-43-9
MW 480.68 g/mol
Grade MOLECULAR BIOLOGY GRADE
Storage/Handling Store at -20°C.
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E-250-10 10 mg $ 52.00
E-250-100 100 mg $ 190.00
E-250-25 25 mg $ 74.00
E-250-50 50 mg $ 111.00

Nicotinamide (Vitamin B3), USP Grade

Catalog ID Size Pricing
N-640-500 500 g $ 104.00

Description

Nicotinamide is a metabolized amide form of vitamin B3. It is an anti-cancer agent and inhibitor of PARP-1, which is responsible for repairing DNA damage caused by chemotherapy. Nicotinamide is converted to nicotinamide adenine dinucleotide (NAD) and nicotinamide adenine dinucleotide phosphate (NADP) for use in biological redox reactions. Additionally, nicotinamide is a nicotinamide phosphoribosyltransferase (NAMPT) substrate and anti-inflammatory agent.

Product Specifications

Catalog ID N-640
CAS # 98-92-0
MW 122.12 g/mol
Storage/Handling Store at 4°C.
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N-640-500 500 g $ 104.00

Amphotericin B, USP Grade

Catalog ID Size Pricing
A-560-250 250 mg $ 49.00
A-560-500 500 mg $ 90.00
A-560-1 1 g $ 137.00
A-560-5 5 g $ 519.00

Description

Amphotericin B is a polyene antifungal isolated from Streptomyces species. While it has been suggested that Amphotericin B interacts with ergosterol of the fungal cell membrane leading to an altered cell membrane permeability and death, more recent studies show that the mechanism behind amphotericin B’s fungicidal activity is more complex. It is most effective against fungi and yeast and is often used against opportunistic fungal infections and leishmaniasis. Additionally, amphotericin B can be used to prevent growth of F. oxysporum in chickpea and P. triticina in wheat.

Product Specifications

Catalog ID A-560
CAS # 1397-89-3
MW 924.08 g/mol
Storage/Handling Store desiccated at 4°C. Protect from light.
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A-560-250 250 mg $ 49.00
A-560-500 500 mg $ 90.00
A-560-1 1 g $ 137.00
A-560-5 5 g $ 519.00

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