Antibiotics & Selection

Antibiotics and Selection tools allow you to selectively control which cells can be found in your cultures.



GoldBio’s broad range of cell selection tools, including hundreds of antibiotics, antifungals and anticancers, plant selection and screening agents allow you to select, control and maintain your cell cultures with confidence and ease, no matter what cells you may be studying.

Showing 41-60 of 275 items.

Gentamicin Sulfate, USP Grade

Catalog ID Size Pricing
G-400-1 1 g $ 23.00
G-400-5 5 g $ 34.00
G-400-10 10 g $ 58.00
G-400-25 25 g $ 88.00
G-400-100 100 g $ 282.00

Description

Gentamicin is an aminoglycoside, broad-spectrum antibiotic that effectively inhibits Gram-negative and Gram-positive cell growth.  Gentamicin's mode of action is to bind to the 30S ribosomal subunit and interfere with protein synthesis.

It is commonly used in clinical in vitro microbiological antimicrobial susceptibility tests (panels, discs, and MIC strips) against gram-positive and gram-negative microbial isolates. Medical microbiologists use AST results to recommend antibiotic treatment options for infected patients.

Product Specifications

Catalog ID G-400
CAS # 1405-41-0
MW 575.67 g/mol
Storage/Handling Store desiccated at -20°C.
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G-400-1 1 g $ 23.00
G-400-5 5 g $ 34.00
G-400-10 10 g $ 58.00
G-400-25 25 g $ 88.00
G-400-100 100 g $ 282.00

Kanamycin Monosulfate, USP Grade

Catalog ID Size Pricing
K-120-5 5 g $ 23.00
K-120-10 10 g $ 44.00
K-120-25 25 g $ 92.00
K-120-50 50 g $ 173.00
K-120-100 100 g $ 323.00
K-120-250 250 g $ 748.00

Description

Kanamycin is an aminoglycoside antibiotic isolated from Streptomyces kanamyceticus. It is effective against gram-positive and gram-negative bacteria as well as Mycoplasma species. Kanamycin is commonly used to select for bacteria that have been transformed with a kanamycin-resistant gene and plant tissues that have the NPT II (APH3) gene incorporated in them. Kanamycin is very soluble in aqueous solution and is typically used in concentrations of 50-100 µg/ml.

Product Specifications

Catalog ID K-120
CAS # 25389-94-0
MW 582.58 g/mol
Storage/Handling Store desiccated at -20°C.
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K-120-5 5 g $ 23.00
K-120-10 10 g $ 44.00
K-120-25 25 g $ 92.00
K-120-50 50 g $ 173.00
K-120-100 100 g $ 323.00
K-120-250 250 g $ 748.00

Lapis-3-Acetate

Catalog ID Size Pricing
B-650-1 1 g $ 76.00
B-650-2.5 2.5 g $ 165.00
B-650-5 5 g $ 288.00
B-650-10 10 g $ 500.00

Description

No description available

Product Specifications

Catalog ID B-650
CAS # 17357-14-1
MW 254.09 g/mol
Grade MOLECULAR BIOLOGY GRADE
Storage/Handling Store at -20°C. Protect from light.
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B-650-1 1 g $ 76.00
B-650-2.5 2.5 g $ 165.00
B-650-5 5 g $ 288.00
B-650-10 10 g $ 500.00

MUG

Catalog ID Size Pricing
MUG200 200 mg $ 19.00
MUG1 1 g $ 58.00
MUG5 5 g $ 233.00
MUG10 10 g $ 370.00
MUG25 25 g $ 741.00

Description

4-Methylumbelliferyl beta-D-glucuronide (MUG) is a fluorogenic substrate for beta-glucuronidase (GUS). Upon cleavage, MUG yields blue fluorescence seen under UV light.

This substrate is commonly used for the detection of Escherichia coli through its ability to detect activity of beta-glucuronidase, which is encoded by uidA. GUS activity is tested in minimal medium o-nitrophenyl-beta-D-galactopyranoside (MMO)-MUG.

It is ideal for plant molecular study as a way to examine gene expression under various promoters. And while it works well for measuring activity in plant lysate and leaf disks, it can also work in whole plant assays.

Product Specifications

Catalog ID MUG
CAS # 6160-80-1 or 881005-91-0
MW 388.32 g/mol
Grade MOLECULAR BIOLOGY GRADE
Storage/Handling Store desiccated at -20°C.
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MUG200 200 mg $ 19.00
MUG1 1 g $ 58.00
MUG5 5 g $ 233.00
MUG10 10 g $ 370.00
MUG25 25 g $ 741.00

N-Methylindoxyl-beta-D- galactopyranoside

Catalog ID Size Pricing
M-480-100 100 mg $ 130.00
M-480-500 500 mg $ 525.00
M-480-5 5 g $ 2,283.00

Description

No description available

Product Specifications

Catalog ID M-480
CAS # 207598-26-3
MW 309.32 g/mol
Storage/Handling Store at -20°C. Protect from light.
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M-480-100 100 mg $ 130.00
M-480-500 500 mg $ 525.00
M-480-5 5 g $ 2,283.00

Nitrotetrazolium blue chloride (NBT)

Catalog ID Size Pricing
NBT1 1 g $ 48.00
NBT2.5 2.5 g $ 98.00
NBT5 5 g $ 158.00
NBT10 10 g $ 254.00

Description

Nitrotetrazolium Blue (NBT) is used in combination with 5-bromo-4-chloro-3-indoxyl phosphate (BCIP) to detect alkaline phosphatase activity in blotting techniques and in situ hybridization chemistry. BCIP acts as the substrate for alkaline phosphatase, and the oxidizing reagent NBT enhances the purple-brown final color of the precipitates at the reaction sites.

NBT has also been used with X-Gal,or Salmon-Gal to speed up and enhance colony screening.

Product Specifications

Catalog ID NBT
CAS # 298-83-9
MW 817.65 g/mol
Grade MOLECULAR BIOLOGY GRADE
Storage/Handling Store at 4°C. Protect from light.
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NBT1 1 g $ 48.00
NBT2.5 2.5 g $ 98.00
NBT5 5 g $ 158.00
NBT10 10 g $ 254.00

Nourseothricin Sulfate (Streptothricin Sulfate) (NTC or clonNAT)

Catalog ID Size Pricing
N-500-100 100 mg $ 73.00
N-500-500 500 mg $ 191.00
N-500-1 1 g $ 273.00
N-500-2 2 x 1 g $ 501.00
N-500-3 3 x 1 g $ 719.00
N-500-4 4 x 1 g $ 916.00
N-500-5 5 x 1 g $ 1,091.00

Description

Nourseothricin is a broad-spectrum antibiotic derived from Streptomyces noursei. In addition to being effective on prokaryotic cells of gram-positive and gram-negative bacteria, various fungi including Candida albicans, and certain DNA and RNA viruses, it is also effective on eukaryotic cells of higher eukaryotes. It has been used as a selection agent for cells containing the gene conferring resistance to it.

Product Specifications

Catalog ID N-500
CAS # 96736-11-7
MW 1359.47 g/mol
Storage/Handling Store desiccated at 4°C.
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N-500-100 100 mg $ 73.00
N-500-500 500 mg $ 191.00
N-500-1 1 g $ 273.00
N-500-2 2 x 1 g $ 501.00
N-500-3 3 x 1 g $ 719.00
N-500-4 4 x 1 g $ 916.00
N-500-5 5 x 1 g $ 1,091.00

Phosphinothricin

Catalog ID Size Pricing
P-165-250 250 mg $ 99.00
P-165-1 1 g $ 281.00
P-165-5 5 g $ 1,059.00

Description

Phosphinothricin is a broad-spectrum herbicide that acts as a competitive inhibitor of glutamine synthetase.

Glutamine synthetase plays an important role in plant nitrogen metabolism. Its actions lead to the formation of glutamine; however, when inhibited by phosphinothricin, a rapid accumulation of ammonia along with reduction in glutamine occurs within plants.

This herbicide makes an ideal agent for the selection of transformed plants. Plant resistance to phosphinothricin is conferred through the bar gene, and due to the fast degradation of phosphinothricin in soil and in water, it presents a low risk for environmental contamination.

Product Specifications

Catalog ID P-165
CAS # 77182-82-2
MW 198.16 g/mol
Storage/Handling Store desiccated at -20°C.
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P-165-250 250 mg $ 99.00
P-165-1 1 g $ 281.00
P-165-5 5 g $ 1,059.00

Rifampicin, USP Grade

Catalog ID Size Pricing
R-120-1 1 g $ 30.00
R-120-5 5 g $ 58.00
R-120-25 25 g $ 156.00
R-120-10 10 g $ 95.00
R-120-50 50 g $ 259.00

Description

Rifampicin is a broad-spectrum antibiotic known for its efficacy against tuberculosis and other infections caused by Mycobacterium species. This semisynthetic antibiotic has also been shown to work against methicillin-resistant Staphylococcus aureus (MRSA), to activate nuclear pregnane x receptor (PXR), and to promote CYP2C-mediated metabolism.

Rifampicin functions by binding the β-subunit of RNA polymerase, inhibiting RNA synthesis. Resistance to this antibiotic develops from mutations on the binding site on RNA polymerase leading to a lower affinity for rifampicin.

Product Specifications

Catalog ID R-120
CAS # 13292-46-1
MW 822.94 g/mol
Storage/Handling Store desiccated at -20°C.
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R-120-1 1 g $ 30.00
R-120-5 5 g $ 58.00
R-120-25 25 g $ 156.00
R-120-10 10 g $ 95.00
R-120-50 50 g $ 259.00

Salmon Gal (6-Chloro-3-indoxyl-β-D-galactopyranoside)

Catalog ID Size Pricing
C-255-500 500 mg $ 47.00
C-255-1 1 g $ 80.00
C-255-2.5 2.5 g $ 177.00
C-255-5 5 g $ 265.00

Description

Salmon Gal (6-Chloro-3-indolyl-β-D-galactopyranoside) is used with IPTG as an alternative chromogenic substrate capable of detecting LacZ gene encoded ß-galactosidase activity for colony screening in colometric assays.

Unlike colony blue/white screening through X-Gal, nonrecombination results in a salmon color after salmon gal is cleaved by ß-galactosidase through hydrolysis. This contrast may be useful in comparative or secondary screenings.

Incorporating nitroblue tetrazolium salt (NBT) into the salmon gal reactions provides faster results with a clear, purple precipitate than in unaccompanied uses of salmon gal.

Product Specifications

Catalog ID C-255
CAS # 138182-21-5
MW 329.73 g/mol
Grade MOLECULAR BIOLOGY GRADE
Storage/Handling Store desiccated at -20°C. Protect from light.
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C-255-500 500 mg $ 47.00
C-255-1 1 g $ 80.00
C-255-2.5 2.5 g $ 177.00
C-255-5 5 g $ 265.00

Spectinomycin Dihydrochloride Pentahydrate, USP Grade

Catalog ID Size Pricing
S-140-5 5 g $ 30.00
S-140-25 25 g $ 92.00
S-140-50 50 g $ 154.00
S-140-250 250 g $ 652.00

Description

Spectinomycin is an aminocyclitol antibiotic isolated from Streptomyces spectabilis. It is effective against gram-positive and gram-negative bacteria, but most commonly used against Gonococcus species. It has also been used to monitor cell fate during leaf development and as a selection marker in plants to display successful transformation of the Spcr gene.

Spectinomycin functions by binding the 30s ribosomal subunit, inhibiting tRNA translation and protein synthesis. Resistance to this antibiotic is conferred through the aadA gene and mutated rpsE gene.

Product Specifications

Catalog ID S-140
CAS # 22189-32-8
MW 495.35 g/mol
Storage/Handling Store desiccated at -20°C.
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S-140-5 5 g $ 30.00
S-140-25 25 g $ 92.00
S-140-50 50 g $ 154.00
S-140-250 250 g $ 652.00

Streptomycin Sulfate, USP Grade

Catalog ID Size Pricing
S-150-50 50 g $ 23.00
S-150-100 100 g $ 34.00

Description

Streptomycin is an aminoglycoside antibiotic primarily effective against gram-negative bacteria and Mycobacterium species. It is commonly used in cell culture media to prevent bacterial contamination. It has also been used to precipitate nucleic acids during protein purification techniques and to study mechanisms of Streptomycin resistance.

Product Specifications

Catalog ID S-150
CAS # 3810-74-0
MW 1457.40 g/mol
Storage/Handling Store desiccated at -20°C.
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S-150-50 50 g $ 23.00
S-150-100 100 g $ 34.00

Tetracycline Hydrochloride

Catalog ID Size Pricing
T-101-25 25 g $ 23.00
T-101-100 100 g $ 58.00

Description


Tetracycline is a broad-spectrum antibiotic targeting gram-negative and gram-positive bacteria. It also displays toxicity against certain eukaryotic cells. Tetracycline is used in multidrug resistance studies and in cell culture applications as a selective agent. Additionally, it promotes expression of the P450 proteins.

Product Specifications

Catalog ID T-101
CAS # 64-75-5
MW 480.90 g/mol
Grade MOLECULAR BIOLOGY GRADE
Storage/Handling Store desiccated at -20°C. Protect from light.
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T-101-25 25 g $ 23.00
T-101-100 100 g $ 58.00

Timentin™ Ticarcillin/Clavulanate (15/1)

Catalog ID Size Pricing
T-104-2 2 g $ 30.00
T-104-10 10 g $ 115.00
T-104-25 25 g $ 168.00
T-104-100 100 g $ 412.00
T-104-250 250 g $ 794.00
T-104-500 500 g $ 1,324.00

Description

Timentin™ is a 15:1 mixture of ticarcillin and clavulanate. Ticarcillin is a penicillin ß-lactam antibiotic, which is susceptible to ß-lactamase degradation. When combined with clavulanate, a ß-lactamase inhibitor, its efficacy is greatly increased. Timentin™ exhibits high activity against gram-negative bacteria and resistant Agrobacterium species.

Product Specifications

Catalog ID T-104
CAS # 4697-14-7; 61177-45-5
MW 665.64 g/mol
Grade MOLECULAR BIOLOGY GRADE
Storage/Handling Store desiccated at -20°C.
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T-104-2 2 g $ 30.00
T-104-10 10 g $ 115.00
T-104-25 25 g $ 168.00
T-104-100 100 g $ 412.00
T-104-250 250 g $ 794.00
T-104-500 500 g $ 1,324.00

TMB dihydrochloride

Catalog ID Size Pricing
TMBHCL2 2 g $ 68.00
TMBHCL10 10 g $ 299.00
TMBHCL25 25 g $ 576.00
TMBHCL50 50 g $ 885.00

Description

No description available

Product Specifications

Catalog ID TMBHCL
CAS # 207738-08-7
MW 313.27 g/mol
Grade MOLECULAR BIOLOGY GRADE
Storage/Handling Store desiccated at -20°C. Protect from light.
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TMBHCL2 2 g $ 68.00
TMBHCL10 10 g $ 299.00
TMBHCL25 25 g $ 576.00
TMBHCL50 50 g $ 885.00

TMB, free base

Catalog ID Size Pricing
TMBF10 10 g $ 65.00
TMBF25 25 g $ 153.00
TMBF50 50 g $ 240.00
TMBF100 100 g $ 436.00

Description

No description available

Product Specifications

Catalog ID TMBF
CAS # 54827-17-7
MW 240.35 g/mol
Grade MOLECULAR BIOLOGY GRADE
Storage/Handling Store desiccated at 4°C. Protect from light.
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TMBF10 10 g $ 65.00
TMBF25 25 g $ 153.00
TMBF50 50 g $ 240.00
TMBF100 100 g $ 436.00

Validamycin A

Catalog ID Size Pricing
V-170-1 1 g $ 104.00

Description

Validamycin is a fungicidal, aminoglycoside antibiotic known to inhibit trehalases in plants, insects, and fungi as well as enhance trehalose accumulation in transgenic plants. It is effective against Pellicularia sasakii and Rhizoctonia solani in plants, but only decreases their virulence instead of exhibiting a fungicidal effect. In addition, validamycin is used to control sheath-blight disease in rice and is most effective against soil-borne pathogens. It is used to study trehalase activity and the synthesis of trehalose.

Product Specifications

Catalog ID V-170
CAS # 37248-47-8
MW 497.49 g/mol
Grade MOLECULAR BIOLOGY GRADE
Storage/Handling Store desiccated at -20°C.
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V-170-1 1 g $ 104.00

Vancomycin Hydrochloride, USP Grade

Catalog ID Size Pricing
V-200-1 1 g $ 50.00
V-200-5 5 g $ 115.00
V-200-25 25 g $ 281.00

Description

Vancomycin hydrochloride is a member of the glycopeptide antibiotic class derived from Streptomyces orientalis. It is effective against gram-positive bacteria and used in studies of antibiotic resistance bacteria and nanoparticle transport studies. Exhibiting low toxicity to plants, vancomycin is suitable for plant selection and prevention of bacterial contamination in plant cell culture applications.

Product Specifications

Catalog ID V-200
CAS # 1404-93-9
MW 1485.71 g/mol
Storage/Handling Store desiccated at -20°C.
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V-200-1 1 g $ 50.00
V-200-5 5 g $ 115.00
V-200-25 25 g $ 281.00

X-α-Gal

Catalog ID Size Pricing
XA250 250 mg $ 81.00
XA500 500 mg $ 150.00
XA1 1 g $ 229.00
XA5 5 g $ 932.00
XA10 10 g $ 1,579.00

Description

X-α-Gal is a chromogenic substrate for α-galactosidase, yielding a blue precipitate. X-α-Gal is used for detecting two-hybrid interactions directly on the culture media. This substrate eliminates the need for β-galactosidase liquid and filter-lift assays in two-hybrid analysis.
Used for species differentiation within the family Enterobacteriaceae and differentiation of Bifidobacteria species from Lactobacilli species.

Product Specifications

Catalog ID XA
CAS # 107021-38-5
MW 408.64 g/mol
Grade MOLECULAR BIOLOGY GRADE
Storage/Handling Store at -20°C. Protect from light.
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XA250 250 mg $ 81.00
XA500 500 mg $ 150.00
XA1 1 g $ 229.00
XA5 5 g $ 932.00
XA10 10 g $ 1,579.00

X-gluc (CHX salt)

Catalog ID Size Pricing
G1281C 100 mg $ 46.00
G1281C1 1 g $ 172.00
G1281C2 2 x 1 g $ 330.00
G1281C3 3 x 1 g $ 472.00
G1281C4 4 x 1 g $ 562.00
G1281C5 5 g $ 652.00

Description

X-Gluc is a chromogenic substrate for beta-glucuronidase (GUS) which is encoded by the gusA (uid A) gene, a widely used reporter gene. Glucuronidase cleaves X-Gluc to produce colorless glucuronic acid and an intense blue precipitate. X-Gluc is often used in GUS staining of plant cells and tissue and in infections caused by E. coli.

Product Specifications

Catalog ID G1281
CAS # 114162-64-0
MW 521.79 g/mol
Grade MOLECULAR BIOLOGY GRADE
Storage/Handling Store desiccated at -20°C. Protect from light.
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G1281C 100 mg $ 46.00
G1281C1 1 g $ 172.00
G1281C2 2 x 1 g $ 330.00
G1281C3 3 x 1 g $ 472.00
G1281C4 4 x 1 g $ 562.00
G1281C5 5 g $ 652.00

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