Bialaphos

Bialaphos is a natural herbicide that is synthesized by Streptomyces hygroscopicus and Streptomyces viridochromeogenes. Bialaphos is made up of two alanine residues and the glutamic acid analog, phosphinothricin, and is commonly used as a gene selector in plants transformed with the bar gene, often called Basta gene. Bialaphos is typically used with cereal grains and is known to be more effective in corn and wheat than glufosinate (phosphinothricin). Bialaphos acts as a prodrug by separating into individual subunits of alanylalanine and phosphinothricin. Bialaphos is toxic to cells by accumulating ammonia and inhibiting photosynthesis and glutamine synthesis.
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Bialaphos, Sodium Salt

Catalog ID Size Pricing
B0178-100 100 mg $ 133.00
B0178-250 250 mg $ 316.00
B0178-500 500 mg $ 580.00

Description

Bialaphos is a tripeptide antibiotic that is used in transformation experiments of many species of plants that make use of the bar gene for selection. In corn, it is more effective than glufosinate. In wheat, bialaphos was the most reliable selection criteria used to identify bar transformed plants.

Once introduced into a nonresistant plant cell, bialaphos is hydrolyzed and converted to phosphinothricin through the phosphinothricin acetyl transferase enzyme. Phosphinothricin is toxic within plants, causing ammonia to build up, which inhibits glutamine synthetase.

This broad-spectrum herbicide also has effectiveness against gram-negative and gram-positive bacteria, as well as certain fungal plant pathogens.

Product Specifications

´╗┐Catalog ID B0178
CAS # 71048-99-2
MW 345.26 g/mol
Grade MOLECULAR BIOLOGY GRADE
Storage/Handling Store desiccated at -20┬░C.
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B0178-100 100 mg $ 133.00
B0178-250 250 mg $ 316.00
B0178-500 500 mg $ 580.00

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