Carbapenems

Carbapenems are a class of β-lactams with broad antibacterial activity. β-lactams interfere with PBP (penicillin binding protein) activity involved in the final phase of peptidoglycan synthesis. PBPs are enzymes that catalyze a pentaglycine cross-link between alanine and lysine residues, providing additional strength to the cell wall. Without a pentaglycine cross-link, the integrity of the cell wall is severely compromised, and ultimately leads to cell lysis and death. Resistance to β-lactams is commonly due to cells containing plasmid encoded β-lactamases. Carbapenems are highly resistant to β-lactamases, and are commonly used as a last resort antibiotic of choice in the medical field due to their broad efficacy against both gram-positive and gram-negative bacteria and their poor oral bioavailabilility.
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Faropenem Sodium

Catalog ID Size Pricing
F-350-50 50 mg $ 251.00

Description

Faropenem sodium is an ultra broad-spectrum β-lactam of the penem antibiotic class. It has been shown to be β-lactamase resistant and is especially effective against anaerobic bacteria responsible for oral infections, but targets a variety of gram-positive and gram-negative bacteria. Faropenem sodium is freely soluble in water.

Product Specifications

Catalog ID F-350
CAS # 122547-49-3
MW 307.30 g/mol
Grade MOLECULAR BIOLOGY GRADE
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F-350-50 50 mg $ 251.00

Meropenem

Catalog ID Size Pricing
M-820-10 10 g $ 279.00
M-820-25 25 g $ 516.00
M-820-50 50 g $ 765.00
M-820-100 100 g $ 1,133.00

Description

Meropenem is a carbapenem β-lactam antibiotic. It targets gram-negative and gram-positive bacteria and displays high resistance to β-lactamase and kidney dehydropeptidase I activity. It is especially effective against bacteria responsible for causing meningitis and exhibits low toxicity when compared to similar antibiotics.

Product Specifications

Catalog ID M-820
CAS # 119478-56-7
MW 437.51 g/mol
Storage/Handling Store desiccated at -20°C.
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M-820-10 10 g $ 279.00
M-820-25 25 g $ 516.00
M-820-50 50 g $ 765.00
M-820-100 100 g $ 1,133.00

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