EGF

Goldbio offers affordable, high quality proteins of the epidermal growth factor (EGF) family of proteins, which all contain a conserved peptide domain known as the EGF-like domain. The sequence of the EGF domain contains six cysteine residues that form three intramolecular disulfide bonds. These disulfide bridges create structural loops that are needed for EGF family members to bind with the ErbB tyrosine kinase receptors. EGF family proteins play important roles in cellular proliferation and differentiation, immune system responses, and apoptotic cell clearance. Unregulated or increased activity of many of the EGF family members and their receptors has been implicated in tumor formation.

Showing 1-6 of 6 items.

EGF, Human

Catalog ID Size Pricing
1150-04-100 100 μg $ 56.00
1150-04-500 500 μg $ 72.00
1150-04-1000 1000 μg $ 80.00

Description

EGF (Epidermal Growth Factor) is a family of growth factors that are derived from membrane-anchored precursors. The family is characterized by the presence of at least one “EGF-like domain” (characterized by the presence of three disulfide bonds, formed from 6 conserved cysteine residues) in their extracellular domain. EGF was originally discovered as an activity that induced early eyelid opening, incisor eruption, hair growth inhibition and stunting of growth when injected into newborn mice. Mature human EGF shares 70% amino acid sequence identity with mature mouse and rat EGF. Human EGF was isolated from urine based on its inhibitory effect on gastric secretion and is sometimes called urogastrone.

Product Specifications

Catalog ID 1150-04
MW ~6.2 kDa
Storage/Handling Store desiccated at -20°C.
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1150-04-100 100 μg $ 56.00
1150-04-500 500 μg $ 72.00
1150-04-1000 1000 μg $ 80.00

EGF, Murine

Catalog ID Size Pricing
1350-04-100 100 μg $ 76.00
1350-04-500 500 μg $ 112.00
1350-04-1000 1000 μg $ 135.00

Description

EGF (Epidermal Growth Factor) is a family of growth factors that are derived from membrane-anchored precursors. The family is characterized by the presence of at least one “EGF-like domain” (characterized by the presence of three disulfide bonds, formed from 6 conserved cysteine residues) in their extracellular domain. EGF was originally discovered as an activity that induced early eyelid opening, incisor eruption, hair growth inhibition and stunting of growth when injected into newborn mice. Additionally, EGF has been shown to inhibit gastric secretion, is involved in wound healing and signals through a receptor known as c-erbB (a class I tyrosine kinase receptor).

Product Specifications

Catalog ID 1350-04
MW ~6.0 kDa
Storage/Handling Store desiccated at -20°C.
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1350-04-100 100 μg $ 76.00
1350-04-500 500 μg $ 112.00
1350-04-1000 1000 μg $ 135.00

EGF, Rat

Catalog ID Size Pricing
1550-04-20 20 μg $ 76.00
1550-04-100 100 μg $ 112.00
1550-04-250 250 μg $ 218.00
1550-04-500 500 μg $ 345.00
1550-04-1000 1000 μg $ 604.00

Description

EGF (Epidermal Growth Factor) is a family of growth factors that are derived from membrane-anchored precursors. The family is characterized by the presence of at least one “EGF-like domain” (characterized by the presence of three disulfide bonds, formed from 6 conserved cysteine residues) in their extracellular domain. EGF was originally discovered as an activity that induced early eyelid opening, incisor eruption, hair growth inhibition and stunting of growth when injected into newborn mice. Additionally, EGF has been shown to inhibit gastric secretion, is involved in wound healing and signals through a receptor known as c-erbB (a class I tyrosine kinase receptor).

Product Specifications

Catalog ID 1550-04
MW ~6.2 kDa
Storage/Handling Store desiccated at -20°C.
View
Quick Add
1550-04-20 20 μg $ 76.00
1550-04-100 100 μg $ 112.00
1550-04-250 250 μg $ 218.00
1550-04-500 500 μg $ 345.00
1550-04-1000 1000 μg $ 604.00

HBEGF, Human

Catalog ID Size Pricing
1150-14-10 10 μg $ 76.00
1150-14-50 50 μg $ 112.00
1150-14-100 100 μg $ 152.00
1150-14-250 250 μg $ 291.00
1150-14-500 500 μg $ 436.00
1150-14-1000 1000 μg $ 781.00

Description

Heparin-binding epidermal growth factor-like growth factor (HBEGF) is synthesized as a transmembrane precursor that is cleaved by a protease to release HBEGF as the ectodomain. Its expression stimulates neurogenesis and is increased after the brain experiences cerebral hypoxia. HBEGF is known to participate in a variety of normal physiological processes such as blastocyst implantation and wound healing, as well as in pathological processes such as tumor growth, SMC hyperplasia and atherosclerosis. HBEGF is a glycoprotein exhibiting mitogenic and chemotactic activity in smooth muscle cells and fibroblasts.

Product Specifications

Catalog ID 1150-14
MW ~9.7 kDa
Storage/Handling Store desiccated at -20°C.
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1150-14-10 10 μg $ 76.00
1150-14-50 50 μg $ 112.00
1150-14-100 100 μg $ 152.00
1150-14-250 250 μg $ 291.00
1150-14-500 500 μg $ 436.00
1150-14-1000 1000 μg $ 781.00

HBEGF, Murine

Catalog ID Size Pricing
1350-08-10 10 μg $ 76.00
1350-08-50 50 μg $ 112.00
1350-08-100 100 μg $ 152.00
1350-08-250 250 μg $ 291.00
1350-08-500 500 μg $ 436.00
1350-08-1000 1000 μg $ 781.00

Description

Heparin-binding epidermal growth factor-like growth factor (HBEGF) is synthesized as a transmembrane precursor that is cleaved by a protease to release HBEGF as the ectodomain. Its expression stimulates neurogenesis and is increased after the brain experiences cerebral hypoxia. HBEGF is known to participate in a variety of normal physiological processes such as blastocyst implantation and wound healing, as well as in pathological processes such as tumor growth, SMC hyperplasia and atherosclerosis. HBEGF is a glycoprotein exhibiting mitogenic and chemotactic activity in smooth muscle cells and fibroblasts.

Product Specifications

Catalog ID 1350-08
MW ~9.7 kDa
Storage/Handling Store desiccated at -20°C.
View
Quick Add
1350-08-10 10 μg $ 76.00
1350-08-50 50 μg $ 112.00
1350-08-100 100 μg $ 152.00
1350-08-250 250 μg $ 291.00
1350-08-500 500 μg $ 436.00
1350-08-1000 1000 μg $ 781.00

HBEGF, Rat

Catalog ID Size Pricing
1550-08-10 10 μg $ 76.00
1550-08-50 50 μg $ 112.00
1550-08-100 100 μg $ 152.00
1550-08-250 250 μg $ 291.00
1550-08-500 500 μg $ 436.00
1550-08-1000 1000 μg $ 781.00

Description

Heparin-binding epidermal growth factor-like growth factor (HBEGF) is synthesized as a transmembrane precursor that is cleaved by a protease to release HBEGF as the ectodomain. Its expression stimulates neurogenesis and is increased after the brain experiences cerebral hypoxia. HBEGF is known to participate in a variety of normal physiological processes such as blastocyst implantation and wound healing, as well as in pathological processes such as tumor growth, SMC hyperplasia and atherosclerosis. HBEGF is a glycoprotein exhibiting mitogenic and chemotactic activity in smooth muscle cells and fibroblasts.

Product Specifications

Catalog ID 1550-08
MW ~9.7 kDa
Storage/Handling Store desiccated at -20°C.
View
Quick Add
1550-08-10 10 μg $ 76.00
1550-08-50 50 μg $ 112.00
1550-08-100 100 μg $ 152.00
1550-08-250 250 μg $ 291.00
1550-08-500 500 μg $ 436.00
1550-08-1000 1000 μg $ 781.00

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