Luciferin

Bioluminescence is the production and emission of light by a living organism. Bioluminescence occurs widely in marine vertebrates and invertebrates, as well as in some fungi, microorganisms and terrestrial invertebrates. Luciferin, the firefly substrate of luciferase, is a common reagent used throughout the biotechnology field. The injection of luciferin allows for the real-time, noninvasive monitoring of disease progression and/or drug efficacy in these model systems through Bioluminescence Imaging (BLI). Coelenterazine is a luminophore is the substrate for many luciferase enzymes, including Renilla reniformis, gaussia, and aequorins. It is commonly used to monitor reporter genes in BRET (Bioluminescence Resonance Energy Transfer), ELISA and HTS methods. Gold Biotechnology’s luciferin and coelenterazine are Proven and Published™ to ensure a quality reagent with optimal potential.
Showing 1-8 of 8 items.

Coelenterazine

Catalog ID Size Pricing
CZ2.5 2.5 mg $ 60.00
CZ5 5 mg $ 93.00
CZ10 10 mg $ 141.00
CZ25 25 mg $ 329.00

Description

Coelenterazine is a luminophore found in aquatic organisms and is the substrate for many luciferase enzymes, including Renilla reniformis, Gaussia and aequorins. It is commonly used for bioluminescent calcium detection and the monitoring of reporter genes in BRET (Bioluminescence Resonance Energy Transfer), ELISA and HTS methods as well as chemiluminescent detection of superoxide anions and peroxynitrite in cells or tissues.

Product Specifications

Catalog ID CZ
CAS # 55779-48-1
MW 423.46 g/mol
Grade MOLECULAR BIOLOGY GRADE
Storage/Handling Store under inert gas at -20°C. Protect from light.
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CZ2.5 2.5 mg $ 60.00
CZ5 5 mg $ 93.00
CZ10 10 mg $ 141.00
CZ25 25 mg $ 329.00

Coelenterazine 400 a

Catalog ID Size Pricing
C-320-1 1 mg $ 73.00
C-320-10 10 mg $ 281.00
C-320-25 25 mg $ 585.00
C-320-50 50 mg $ 963.00

Description

Coelenterazine 400A is a derivative of coelenterazine and is a good substrate for Renilla reniformis luciferase (RLuc), but does not oxidize well with Gaussia (GLuc). It is the preferred substrate for BRET (Bioluminescence Resonance Energy Transfer) since its emission maximum of 400nm has minimal interference with the GFP emission.

Product Specifications

Catalog ID C-320
CAS # 70217-82-2
MW 391.48 g/mol
Grade MOLECULAR BIOLOGY GRADE
Storage/Handling Store at -20°C. Protect from light.
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C-320-1 1 mg $ 73.00
C-320-10 10 mg $ 281.00
C-320-25 25 mg $ 585.00
C-320-50 50 mg $ 963.00

D-Luciferin Firefly, free acid (Proven and Published™)

Catalog ID Size Pricing
L-123-10 10 mg $ 51.00
L-123-250 250 mg $ 124.00
L-123-500 500 mg $ 209.00
L-123-1 1 g $ 276.00

Description

Tested and Certified for in vivo imaging (See "Luciferin FAQ" in additional information)

Luciferin is a common bioluminescent reporter used for in vivo imaging of the expression of luciferase. This substrate for the firefly luciferase enzyme utilizes ATP and Mg2+ as cofactors to emit a characteristic yellow-green emission in the presence of oxygen, which shifts to red light in vivo at 37°C. Through the utilization of ATP, the reaction can be further used to indicate the presence of energy or life in order to function as a life-death stain.

Luciferin is a common reagent used throughout the biotechnology field and specifically for in vivo imaging. Luciferase labeled tumor cells, stem cells or infectious diseases are often inoculated into research animals such as rats or mice for investigation. The injection of luciferin allows for the real-time, noninvasive monitoring of disease progression and/or drug efficacy in these model systems through Bioluminescence Imaging (BLI).

Luciferin is also commonly used for in vitro research, including luciferase and ATP assays, gene reporter assays, high throughput sequencing and various contamination assays.

Firefly Luciferin is identical to Beetle Luciferin. (See "Additional Information" for structures.)

Product Specifications

Catalog ID L-123
CAS # 2591-17-5
MW 280.33 g/mol
Grade MOLECULAR BIOLOGY GRADE
Storage/Handling Store desiccated at -20°C. Protect from light.
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L-123-10 10 mg $ 51.00
L-123-250 250 mg $ 124.00
L-123-500 500 mg $ 209.00
L-123-1 1 g $ 276.00

D-Luciferin, Potassium Salt (Proven and Published™)

Catalog ID Size Pricing
LUCK-100 100 mg $ 52.00
LUCK-1G 1 g $ 245.00
LUCK-500 500 mg $ 188.00
LUCK-300 300 mg $ 146.00
LUCK-2G 2 x 1 g $ 472.00
LUCK-3G 3 x 1 g $ 702.00
LUCK-4G 4 x 1 g $ 928.00
LUCK-5G 5 x 1 g $ 1,150.00
LUCK-10G 10 x 1 g $ 2,280.00
LUCK-250 250 mg $ 125.00

Description

Luciferin is a common bioluminescent reporter used for in vivo imaging of the expression of luciferase. This water soluble substrate for the firefly luciferase enzyme utilizes ATP and Mg2+ as cofactors to emit a characteristic yellow-green emission in the presence of oxygen, which shifts to red light in vivo at 37°C. Through the utilization of ATP, the reaction can be further used to indicate the presence of energy or life in order to function as a life-death stain.

Luciferin is a common reagent used throughout the biotechnology field and specifically for in vivo imaging. Luciferase labeled tumor cells, stem cells or infectious diseases are often inoculated into research animals such as rats or mice for investigation. The injection of luciferin allows for the real-time, noninvasive monitoring of disease progression and/or drug efficacy in these model systems through Bioluminescence Imaging (BLI).

Luciferin is also commonly used for in vitro research, including luciferase and ATP assays, gene reporter assays, high throughput sequencing and various contamination assays.

Firefly Luciferin is identical to Beetle Luciferin. (See "Additional Information" for structures.)

Product Specifications

Catalog ID LUCK
CAS # 115144-35-9
MW 318.42 g/mol
Grade MOLECULAR BIOLOGY GRADE
Storage/Handling Store desiccated at -20°C. Protect from light.
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LUCK-100 100 mg $ 52.00
LUCK-1G 1 g $ 245.00
LUCK-500 500 mg $ 188.00
LUCK-300 300 mg $ 146.00
LUCK-2G 2 x 1 g $ 472.00
LUCK-3G 3 x 1 g $ 702.00
LUCK-4G 4 x 1 g $ 928.00
LUCK-5G 5 x 1 g $ 1,150.00
LUCK-10G 10 x 1 g $ 2,280.00
LUCK-250 250 mg $ 125.00

D-Luciferin, Sodium Salt (Proven and Published™)

Catalog ID Size Pricing
LUCNA-300 300 mg $ 146.00
LUCNA-1G 1 g $ 245.00
LUCNA-100 100 mg $ 52.00
LUCNA-500 500 mg $ 188.00
LUCNA-2G 2 x 1 g $ 472.00
LUCNA-3G 3 x 1 g $ 702.00
LUCNA-4G 4 x 1 g $ 928.00
LUCNA-5G 5 x 1 g $ 1,150.00
LUCNA-10G 10 x 1 g $ 2,280.00
LUCNA-250 250 mg $ 125.00

Description

Tested and Certified for in vivo imaging (See "Luciferin FAQ" in additional information)

Luciferin is a common bioluminescent reporter used for in vivo imaging of the expression of luciferase. This water soluble substrate for the firefly luciferase enzyme utilizes ATP and Mg2+ as cofactors to emit a characteristic yellow-green emission in the presence of oxygen, which shifts to red light in vivo at 37°C. Through the utilization of ATP, the reaction can be further used to indicate the presence of energy or life in order to function as a life-death stain.

Luciferin is a common reagent used throughout the biotechnology field and specifically for in vivo imaging. Luciferase labeled tumor cells, stem cells or infectious diseases are often inoculated into research animals such as rats or mice for investigation. The injection of luciferin allows for the real-time, noninvasive monitoring of disease progression and/or drug efficacy in these model systems through Bioluminescence Imaging (BLI).

Luciferin is also commonly used for in vitro research, including luciferase and ATP assays, gene reporter assays, high throughput sequencing and various contamination assays.

Firefly Luciferin is identical to Beetle Luciferin. (See "Additional Information" for structures.)

Product Specifications

Catalog ID LUCNA
CAS # 103404-75-7
MW 320.32 g/mol
Grade MOLECULAR BIOLOGY GRADE
Storage/Handling Store desiccated at -20°C. Protect from light.
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LUCNA-300 300 mg $ 146.00
LUCNA-1G 1 g $ 245.00
LUCNA-100 100 mg $ 52.00
LUCNA-500 500 mg $ 188.00
LUCNA-2G 2 x 1 g $ 472.00
LUCNA-3G 3 x 1 g $ 702.00
LUCNA-4G 4 x 1 g $ 928.00
LUCNA-5G 5 x 1 g $ 1,150.00
LUCNA-10G 10 x 1 g $ 2,280.00
LUCNA-250 250 mg $ 125.00

DMNPE-caged Luciferin

Catalog ID Size Pricing
L-130-10 10 mg $ 68.00
L-130-25 25 mg $ 155.00
L-130-50 50 mg $ 279.00
L-130-100 100 mg $ 508.00

Description

Tested and Certified for in vivo imaging (See "Luciferin FAQ" in additional information)

Luciferin is a common bioluminescent reporter used for in vivo imaging of the expression of the luciferase . This substrate for the firefly luciferase enzyme utilizes ATP and Mg2+ as cofactors and emits a characteristic yellow-green emission in the presence of oxygen, which shifts to red light in vivo at 37°C.

Luciferin is a common reagent used throughout the biotechnology field and specifically for in vivo imaging. Luciferase labeled tumor cells, stem cells or infectious diseases are often inoculated into research animals such as rats or mice for investigation. The injection of luciferin allows for the real-time, noninvasive monitoring of disease progression and/or drug efficacy in these model systems through Bioluminescence Imaging (BLI).

DMNPE-caged luciferin can be used to measure intracellular functions since it readily crosses cell membranes. Once it is inside the cell, active luciferin can be released by UV light or by the action of endogenous intracellular esterases. DMNPE-caged luciferin makes it easier to follow the changes in gene expression in live cells. It can also be used in combination with DMNPE-caged ATP. 

Product Specifications

Catalog ID L-130
CAS # 223920-67-0
MW 489.53 g/mol
Grade MOLECULAR BIOLOGY GRADE
Storage/Handling Store desiccated at -20°C. Protect from light.
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L-130-10 10 mg $ 68.00
L-130-25 25 mg $ 155.00
L-130-50 50 mg $ 279.00
L-130-100 100 mg $ 508.00

DMNPE-caged Luciferin (DL)

Catalog ID Size Pricing
L-140-50 50 mg $ 182.00

Description

Tested and Certified for in vivo imaging (See "Luciferin FAQ" in additional information)

Luciferin is a common bioluminescent reporter used for in vivo imaging of the expression of the luciferase . This substrate for the firefly luciferase enzyme utilizes ATP and Mg2+ as cofactors and emits a characteristic yellow-green emission in the presence of oxygen, which shifts to red light in vivo at 37°C.

Luciferin is a common reagent used throughout the biotechnology field and specifically for in vivo imaging. Luciferase labeled tumor cells, stem cells, or infectious diseases are often inoculated into research animals such as rats or mice for investigation. The injection of luciferin allows for the real-time, noninvasive monitoring of disease progression and/or drug efficacy in these model systems through bioluminescence Imaging (BLI).

DMNPE-caged luciferin can be used to measure intracellular functions since it readily crosses cell membranes. Once it is inside the cell, active luciferin can be released by UV light or by the action of endogenous intracellular esterases. DMNPE-caged luciferin makes it easier to follow the changes in gene expression in live cells. It can also be used in combination with DMNPE-caged ATP.

DL is a racemic mixture of D-Luciferin and L-Luciferin.

Product Specifications

Catalog ID L-140
CAS # 154140-55-3
MW 489.53 g/mol
Grade MOLECULAR BIOLOGY GRADE
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L-140-50 50 mg $ 182.00

L-Luciferin, potassium salt

Catalog ID Size Pricing
L-127-10 10 mg $ 70.00
L-127-100 100 mg $ 293.00
L-127-250 250 mg $ 611.00
L-127-500 500 mg $ 1,018.00

Description

Tested and Certified for in vivo imaging (See "Luciferin FAQ" in additional information)

Luciferin is a common bioluminescent reporter used for in vivo imaging of the expression of luciferase. This water soluble substrate for the firefly luciferase enzyme utilizes ATP and Mg2+ as cofactors to emit a characteristic yellow-green emission in the presence of oxygen, which shifts to red light in vivo at 37°C. Through the utilization of ATP, the reaction can be further used to indicate the presence of energy or life in order to function as a life-death stain.

Luciferin is a common reagent used throughout the biotechnology field and specifically for in vivo imaging. Luciferase labeled tumor cells, stem cells or infectious diseases are often inoculated into research animals such as rats or mice for investigation. The injection of Luciferin allows for the real-time, noninvasive monitoring of disease progression and/or drug efficacy in these model systems through Bioluminescence Imaging (BLI).

Luciferin is also commonly used for in vitro research, including luciferase and ATP assays, gene reporter assays, high throughput sequencing and various contamination assays.

L-Luciferin is the chiralic sister to D-luciferin. While most researchers claim that L-luciferin does not produce any light, Lembert has reported that it produces a very weak and extremely slow manifesting light (Lembert, 1996). Nakamura suggested that an enzyme system incorporating luciferase might be responsible for changing the chirality of the L-luciferin to D-luciferin (Nakamura et al., 2006) (See Reference Library).

Product Specifications

Catalog ID L-127
CAS # not available
MW 318.42 g/mol
Storage/Handling Store desiccated at -20°C. Protect from light.
View
Quick Add
L-127-10 10 mg $ 70.00
L-127-100 100 mg $ 293.00
L-127-250 250 mg $ 611.00
L-127-500 500 mg $ 1,018.00

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