Pharmaceutical Intermediates

Gold Biotechnology carries a variety of pharmaceutical intermediates that act as a building block for the production of active pharmaceutical ingredients (APIs). These products include agonists, antagonists, amino acids, bile acids, alcohols, aldehydes, ketones, lipids, carbohydrates and many others. GoldBio’s superior pharmaceutical intermediates are meant for research only, and are offered at a much lower rate than other commercially available products, providing you with the highest value possible.
Showing 1-20 of 134 items.

(+)-Bicuculline

Catalog ID Size Pricing
B-040-25 25 mg $ 52.00
B-040-100 100 mg $ 107.00

Description

(+)-Bicuculline, a light-sensitive competitive GABAA and GABAA-gated chloride channel antagonist, functions in the biochemical field as a drug, CNS stimulator, convulsant and neurotransmitter. Its chemical identities are alkaloid and phthalide-isoquinoline compound. Extracted from plant alkaloid in 1932, this metabolite has been definitively located in Adlumia fungosa, Dicentra cucullaria, Fumariaceae and some species of Corydalis. (+)-Bicuculline acts primarily on ionotropic GABAA receptors but also blocks Ca2+-activated potassium channels and can act as an agrochemical.

As a poisonous neurotoxin, it affects nervous system responses associated with GABAA by binding to the receptors but not activating them, thus inhibiting the action of gamma-aminobutyric acid. This produces a powerful convulsive reaction mimicking epilepsy and has been used in lab studies of the condition. Administered with NMDA, it has induced paraplegia. Injection to the amygdala has also produced GABA-related anxiolytic effects on emotional states.

Product Specifications

Catalog ID B-040
CAS # 485-49-4
MW 367.35 g/mol
UN Number 1544
Item Class 6.1
Group Number II
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B-040-25 25 mg $ 52.00
B-040-100 100 mg $ 107.00

1,2,3,4-Tetra-O-acetyl-β-D-glucuronic acid methyl ester

Catalog ID Size Pricing
T-180-100 100 g $ 185.00
T-180-250 250 g $ 385.00
T-180-500 500 g $ 641.00
T-180-1 1 kg $ 1,067.00
T-180-2.5 2.5 kg $ 2,223.00

Description

1,2,3,4-Tetra-O-acetyl-β-D-glucuronic acid methyl ester has been used in various biochemical studies. It has been used to study the potential of water-soluble camptothecin glucuronide derivatives as a cancer prodrug monotherapy and antibody-directed enzyme prodrug therapy. Additionally, it has been used to assess the role of glycosylthio heterocycles in carbohydrates.

Product Specifications

Catalog ID T-180
CAS # 7355-18-2
MW 376.32 g/mol
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T-180-100 100 g $ 185.00
T-180-250 250 g $ 385.00
T-180-500 500 g $ 641.00
T-180-1 1 kg $ 1,067.00
T-180-2.5 2.5 kg $ 2,223.00

1,2-Dimyristoyl-rac-glycerol

Catalog ID Size Pricing
D-515-500 500 mg $ 77.00
D-515-1 1 g $ 127.00
D-515-2.5 2.5 g $ 230.00
D-515-5 5 g $ 398.00
D-515-10 10 g $ 685.00

Description

1,2-Dimyristoyl-rac-glycerol is a carboxylic ester, glycerolipid and diglyceride with an attached myristoyl group, promoting interactions between proteins and lipids. It can be employed as a detergent or reagent. It’s functional in cell biology experimentation concerning metabolism and metabolic pathways involving glycerolipids.

As a diglyceride, the substance consists of two fatty acid chains covalently bonded to the glycerol molecule in the 1,2- formation. Diglyceride (DAG) research investigates the process of suppressing fat accumulation through DAG consumption.

Product Specifications

Catalog ID D-515
CAS # 20255-94-1
MW 512.81 g/mol
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D-515-500 500 mg $ 77.00
D-515-1 1 g $ 127.00
D-515-2.5 2.5 g $ 230.00
D-515-5 5 g $ 398.00
D-515-10 10 g $ 685.00

1,2-Dipalmitoyl-sn-glycero-3-phosphoethanolamine

There is no image for 1,2-Dipalmitoyl-sn-glycero-3-phosphoethanolamine 1,2-Dipalmitoyl-sn-glycero-3-phosphoethanolamine
Catalog ID Size Pricing
D-216-500 500 mg $ 193.00
D-216-1 1 g $ 351.00
D-216-2.5 2.5 g $ 797.00
D-216-5 5 g $ 1,449.00
D-216-10 10 g $ 2,760.00

Description

1,2-Dipalmitoyl-sn-glycero-3-phosphoethanolamine or DPPE is a phospholipid component of the cell membrane. It is used in membrane models and is part of the glycerophosphoethanolamine family. DPPE has been shown to cause competitive hydrogen bonding of amine groups with phosphate/carbonyl groups or water. Additionally, DPPE has been studied along with cholesterol, showing cholesterol’s ability to induce DPPE monolayer condensation when calcium ions are present.

Product Specifications

Catalog ID D-216
CAS # 923-61-5
MW 691.98 g/mol
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D-216-500 500 mg $ 193.00
D-216-1 1 g $ 351.00
D-216-2.5 2.5 g $ 797.00
D-216-5 5 g $ 1,449.00
D-216-10 10 g $ 2,760.00

1,2-Octanediol

There is no image for 1,2-Octanediol 1,2-Octanediol
Catalog ID Size Pricing
O-125-2.5 2.5 kg $ 387.00
O-125-5 5 kg $ 619.00
O-125-10 10 kg $ 989.00
O-125-25 25 kg $ 1,980.00
O-125-50 50 kg $ 3,159.00

Description

1,2-Octanediol has a variety of applications. It is used to improve HPLC separation of organic acids and bases and to synthesize halohydrin palmitates. Additionally, it is studied for its potential use as a pediculicide and has been shown to be effective against louse infestations.

Product Specifications

Catalog ID O-125
CAS # 1117-86-8
MW 146.23 g/mol
Storage/Handling Store at room temperature.
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O-125-2.5 2.5 kg $ 387.00
O-125-5 5 kg $ 619.00
O-125-10 10 kg $ 989.00
O-125-25 25 kg $ 1,980.00
O-125-50 50 kg $ 3,159.00

1-O-Methyl-β-D-glucopyranoside

Catalog ID Size Pricing
M-285-5 5 g $ 56.00
M-285-25 25 g $ 180.00
M-285-50 50 g $ 300.00
M-285-100 100 g $ 500.00
M-285-250 250 g $ 1,125.00

Description

1-O-Methyl-β-D-glucopyranoside is commonly used to study the specificity of yeast Saccharomyces cerevisiae in removing carbohydrates by fermentation. Additionally, it has been used to analyze alternansucrase acceptor reactions with methyl hexopyranosides.

Product Specifications

Catalog ID M-285
CAS # 709-50-2
MW 194.19 g/mol
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M-285-5 5 g $ 56.00
M-285-25 25 g $ 180.00
M-285-50 50 g $ 300.00
M-285-100 100 g $ 500.00
M-285-250 250 g $ 1,125.00

2,2'-Bipyridine

Catalog ID Size Pricing
D-238-100 100 g $ 110.00
D-238-250 250 g $ 176.00
D-238-500 500 g $ 318.00
D-238-1 1 kg $ 604.00
D-238-2.5 2.5 kg $ 1,438.00

Description

2,2’-Bipyridine is a metalloprotease inhibitor used as a reagent for the colorimetric determination of iron. It is a base used for oxidation-reductions indicators and to confirm the presence of ferrous iron in soils. Additionally, 2,2’-bipyridine is used in transition metal catalysis and aluminum-initiated polymerization. It is a high-affinity iron chelator and may inhibit iron-containing enzymes.

Product Specifications

Catalog ID D-238
CAS # 366-18-7
MW 156.19 g/mol
Grade MOLECULAR BIOLOGY GRADE
Storage/Handling Store at 4°C. Protect from light.
UN Number 2811
Item Class 6.1
Group Number III
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D-238-100 100 g $ 110.00
D-238-250 250 g $ 176.00
D-238-500 500 g $ 318.00
D-238-1 1 kg $ 604.00
D-238-2.5 2.5 kg $ 1,438.00

2,4,6-Tris(2-pyridyl)-1,3,5-triazine

Catalog ID Size Pricing
T-113-25 25 g $ 288.00
T-113-50 50 g $ 542.00
T-113-100 100 g $ 1,034.00
T-113-250 250 g $ 2,459.00
T-113-500 500 g $ 4,667.00

Description

2,4,6-Tris(2-pyridyl)-1,3,5-triazine or TPTZ is a triazine compound containing 3 pyridyl groups. It is commonly used as a reagent for the spectrophotometric determination of Fe(II) and total Fe. It can also be used to determine the amount of acetaminophen in samples through spectrophotometry.

Product Specifications

Catalog ID T-113
CAS # 3682-35-7
MW 312.34 g/mol
Grade MOLECULAR BIOLOGY GRADE
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T-113-25 25 g $ 288.00
T-113-50 50 g $ 542.00
T-113-100 100 g $ 1,034.00
T-113-250 250 g $ 2,459.00
T-113-500 500 g $ 4,667.00

2-Aminoisobutyric acid

Catalog ID Size Pricing
A-251-1000 1 kg $ 64.00
A-251-2 2 kg $ 121.00
A-251-10 10 kg $ 1,375.00
A-251-25 25 kg $ 2,750.00
A-251-50 50 kg $ 4,675.00

Description

2-Aminoisobutyric acid is researched for its use in the prediction of type 2 diabetes. As a component in the alanine cycle, 2-aminoisobutyric acid contributes to the regulation of alanine aminotransferases making it useful in diabetes diagnostics.

Product Specifications

Catalog ID A-251
CAS # 62-57-7
MW 103.12 g/mol
Grade MOLECULAR BIOLOGY GRADE
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A-251-1000 1 kg $ 64.00
A-251-2 2 kg $ 121.00
A-251-10 10 kg $ 1,375.00
A-251-25 25 kg $ 2,750.00
A-251-50 50 kg $ 4,675.00

2-Deoxy-D-galactose

Catalog ID Size Pricing
D-090-1 1 g $ 50.00
D-090-2 2 g $ 77.00
D-090-5 5 g $ 138.00
D-090-10 10 g $ 248.00
D-090-25 25 g $ 468.00

Description

2-Deoxy-D-galactose is a deoxy hexose that inhibits synthesis of glycoproteins in Influenza virus, such as hemagglutinin and neuraminidase, by blocking glycosylation. 2-Deoxy-D-galactose also inhibits the glycosylation of mammalian proteins involved in neurotransmitter release and synaptogenesis in the hippocampus. It has been used for isolating galactose permease mutants of Salmonella typhimurium and in the inhibition of glycolysis in Saccharomyces cerevisiae. It has also been used to isolate and elucidate the activity of a system for galactose uptake into E. coli.

Product Specifications

Catalog ID D-090
CAS # 1949-89-9
MW 164.16 g/mol
Grade MOLECULAR BIOLOGY GRADE
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D-090-1 1 g $ 50.00
D-090-2 2 g $ 77.00
D-090-5 5 g $ 138.00
D-090-10 10 g $ 248.00
D-090-25 25 g $ 468.00

2-Nitrophenyl-β-D-galactopyranoside

Catalog ID Size Pricing
N-275-5 5 g $ 21.00
N-275-10 10 g $ 32.00
N-275-25 25 g $ 59.00
N-275-50 50 g $ 92.00
N-275-100 100 g $ 150.00

Description

2-Nitrophenyl-β-D-galactopyranoside or ONPG is a chromogenic substrate for β-galactosidase. Upon hydrolysis, ONPG releases galactose along with a chromogenic yellow compound. Additionally, ONPG is a substrate useful for the determination of β-glucosidases.

Product Specifications

Catalog ID N-275
CAS # 369-07-3
MW 301.26 g/mol
Storage/Handling Store at -20°C. Protect from light.
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N-275-5 5 g $ 21.00
N-275-10 10 g $ 32.00
N-275-25 25 g $ 59.00
N-275-50 50 g $ 92.00
N-275-100 100 g $ 150.00

3-Indoxyl-3-acetate

Catalog ID Size Pricing
I-425-10 10 g $ 185.00
I-425-25 25 g $ 442.00
I-425-50 50 g $ 842.00
I-425-100 100 g $ 1,600.00
I-425-250 250 g $ 3,792.00

Description

3-Indoxyl-3-acetate is a chromogenic substrate used to differentiate between esterases of various microorganism species.

Product Specifications

Catalog ID I-425
CAS # 608-08-2
MW 175.19 g/mol
Storage/Handling Store at -20°C. Protect from light.
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I-425-10 10 g $ 185.00
I-425-25 25 g $ 442.00
I-425-50 50 g $ 842.00
I-425-100 100 g $ 1,600.00
I-425-250 250 g $ 3,792.00

4-Benzyloxyindole

Catalog ID Size Pricing
B-135-10 10 g $ 44.00
B-135-25 25 g $ 77.00
B-135-50 50 g $ 132.00
B-135-100 100 g $ 220.00
B-135-250 250 g $ 424.00

Description

4-Benzyloxyindole is a reactant in a variety of preparation procedures. It is used in the synthesis of 4-aryl-4H-chromenes as an inducer of apoptosis, in the synthesis of indol-3-yl tetramethylcyclopropyl ketones as a CB2 cannabinoid receptor ligand, and in the synthesis of hepatitis C inhibitors. Additionally, 4-Benzyloxyindole is used to prepare carbon-11-labeled-4-aryl-4H-chromenes as PET agents in cancer studies, to prepare indoles through Bartoli reductive cyclization, and to synthesize oxopyrrolidine analogs in iodine-catalyzed Markovnikov additions.

Product Specifications

Catalog ID B-135
CAS # 20289-26-3
MW 223.28 g/mol
Grade MOLECULAR BIOLOGY GRADE
Storage/Handling Store at 4°C.
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B-135-10 10 g $ 44.00
B-135-25 25 g $ 77.00
B-135-50 50 g $ 132.00
B-135-100 100 g $ 220.00
B-135-250 250 g $ 424.00

4-Bromoindole

Catalog ID Size Pricing
B-570-10 10 g $ 66.00
B-570-25 25 g $ 152.00
B-570-50 50 g $ 275.00
B-570-100 100 g $ 528.00
B-570-250 250 g $ 1,265.00

Description

4-Bromoindole is studied for its potential use as a GSK-3 inhibitor.

Product Specifications

Catalog ID B-570
CAS # 52488-36-5
MW 196.05 g/mol
Grade MOLECULAR BIOLOGY GRADE
Storage/Handling Store at 4°C. Protect from light.
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B-570-10 10 g $ 66.00
B-570-25 25 g $ 152.00
B-570-50 50 g $ 275.00
B-570-100 100 g $ 528.00
B-570-250 250 g $ 1,265.00

4-Methoxyindole

Catalog ID Size Pricing
M-170-10 10 g $ 88.00
M-170-25 25 g $ 218.00
M-170-50 50 g $ 429.00
M-170-100 100 g $ 847.00
M-170-250 250 g $ 2,090.00

Description

4-Methoxyindole is used in a variety of preparation procedures. It is a reactant involved in the synthesis of GABA analogs, HIV-1 integrase inhibitors, anticancer agents, sodium-dependent glucose co-transporter 2 (SGLT2) inhibitors, integrase strand-transfer inhibitors (INSTIs), and isomeridianin G. Additionally, it is used in reverse-phase liquid chromatography analysis of the reaction of β-cyclodextrin and pindolol.

Product Specifications

Catalog ID M-170
CAS # 4837-90-5
MW 147.18 g/mol
Grade MOLECULAR BIOLOGY GRADE
Storage/Handling Store at 4°C. Protect from light.
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M-170-10 10 g $ 88.00
M-170-25 25 g $ 218.00
M-170-50 50 g $ 429.00
M-170-100 100 g $ 847.00
M-170-250 250 g $ 2,090.00

4-Methyl-DL-tryptophan

Catalog ID Size Pricing
M-492-1 1 g $ 349.00
M-492-2.5 2.5 g $ 728.00
M-492-5 5 g $ 1,212.00
M-492-10 10 g $ 2,020.00
M-492-25 25 g $ 4,209.00

Description

4-Methyl-DL-tryptophan is a derivative of tryptophan and ATB0 inhibitor. Additionally, it is involved in glycine uptake.

Product Specifications

Catalog ID M-492
CAS # 1954-45-6
MW 218.26 g/mol
Grade MOLECULAR BIOLOGY GRADE
Storage/Handling Store at 4°C. Protect from light.
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M-492-1 1 g $ 349.00
M-492-2.5 2.5 g $ 728.00
M-492-5 5 g $ 1,212.00
M-492-10 10 g $ 2,020.00
M-492-25 25 g $ 4,209.00

4-Methylumbelliferone

Catalog ID Size Pricing
M-499-25 25 g $ 23.00
M-499-250 250 g $ 56.00
M-499-500 500 g $ 85.00
M-499-1 1 kg $ 157.00

Description

4-Methylumbelliferone is useful as an indicator in the determination of nitric acid. It is also useful in the kinetic investigation of enzyme activity. 4-Methylumbelliferone is fluorescent in alkaline solution.

Product Specifications

Catalog ID M-499
CAS # 90-33-5
MW 176.17 g/mol
Grade MOLECULAR BIOLOGY GRADE
Storage/Handling Store at room temperature.
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M-499-25 25 g $ 23.00
M-499-250 250 g $ 56.00
M-499-500 500 g $ 85.00
M-499-1 1 kg $ 157.00

4-Methylumbelliferyl a-L-idopyranosiduronic acid sodium salt

Catalog ID Size Pricing
M-490-10 10 mg $ 509.00
M-490-25 25 mg $ 1,156.00
M-490-50 50 mg $ 2,101.00
M-490-100 100 mg $ 3,820.00

Description

4-Methylumbelliferyl alpha-L-idopyranosiduronic acid sodium salt is a carbohydrate acid and organic sodium salt applied as an indicator. It is the fluorogenic substrate used in assays of α-L-Iduronidase and iduronate-2-sulfatase for identifying Hurler syndrome, also called mucopolysaccharidosis type I (MPS I). The disorder is characterized by α -L iduronidase enzyme deficiency, resulting in the buildup of glucosaminoglycans. Tests measure the chemical products 4-MU-α-IdoA or fluorophate 4-MU emitted following the enzymatic action of 4-Methylumbelliferyl alpha-L-idopyranosiduronic acid sodium salt. The substance is a white crystalline powder and is soluble in ethanol, methanol and water.

Product Specifications

Catalog ID M-490
CAS # 89157-94-8
MW 374.27 g/mol
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M-490-10 10 mg $ 509.00
M-490-25 25 mg $ 1,156.00
M-490-50 50 mg $ 2,101.00
M-490-100 100 mg $ 3,820.00

4-Nitroindole

Catalog ID Size Pricing
N-155-25 25 g $ 69.00
N-155-50 50 g $ 121.00
N-155-100 100 g $ 207.00
N-155-250 250 g $ 963.00
N-155-500 500 g $ 1,898.00

Description

4-Nitroindole is used in the synthesis of a variety of compounds including: indoles, nucleosides, CB2 cannabinoid receptor ligands, CGRP receptor antagonists, anti-angiogenic agents, meridianin derivatives, tryptophan dioxygenase inhibitors, and 1,3,4,5-tetrahydropyrrolo-[4,3,2-de]quinoline.

Product Specifications

Catalog ID N-155
CAS # 4769-97-5
MW 162.15 g/mol
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N-155-25 25 g $ 69.00
N-155-50 50 g $ 121.00
N-155-100 100 g $ 207.00
N-155-250 250 g $ 963.00
N-155-500 500 g $ 1,898.00

4-Nitrophenyl-β-D-galactopyranoside-6-phosphate, bis(cyclohexylammonium) salt

Catalog ID Size Pricing
N-295-50 50 mg $ 73.00
N-295-100 100 mg $ 122.00
N-295-2.5 2.5 g $ 245.00
N-295-250 250 mg $ 245.00
N-295-500 500 mg $ 395.00
N-295-1 1 g $ 637.00

Description

No description available

Product Specifications

Catalog ID N-295
MW 579.59 g/mol
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N-295-50 50 mg $ 73.00
N-295-100 100 mg $ 122.00
N-295-2.5 2.5 g $ 245.00
N-295-250 250 mg $ 245.00
N-295-500 500 mg $ 395.00
N-295-1 1 g $ 637.00

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