Plant Selective Agents

Plant selective agents allow you to modify plant behavior to create herbicide resistant plants in both lab and commercial environments. GoldBio offers both bialaphos and phosphinothricin (also known as Glufosinate), both used in selection regarding the bar gene and on LibertyLinkTM herbicide resistant plants. These tools enable you to use herbicide selection over a wide range of plants, enabling clear results with ease.
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Actinomycin D, USP Grade

There is no image for Actinomycin D, USP Grade Actinomycin D, USP Grade
Catalog ID Size Pricing
A-360-10 10 mg $ 132.00
A-360-25 25 mg $ 226.00

Description

Actinomycin D is an antineoplastic antibiotic from Streptomyces species that inhibits cell proliferation by acting as a cytotoxic inducer of apoptosis against tumor cells, binding to DNA and inhibiting RNA polymerase activity. Actinomycin is also used in plant tissue culture to inhibit plant growth through tissue deformation where it also acts as an RNA-synthesis inhibitor. Along with its fluorescent derivative, 7aminoactinomycinD (7-AAD), Actinomycin is used to stain GC-rich regions of DNA for microscopy and flow cytometry applications.

Product Specifications

Catalog ID A-360
CAS # 50-76-0
MW 1255.41 g/mol
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A-360-10 10 mg $ 132.00
A-360-25 25 mg $ 226.00

Bialaphos, Sodium Salt

Catalog ID Size Pricing
B0178-100 100 mg $ 133.00
B0178-250 250 mg $ 316.00
B0178-500 500 mg $ 580.00

Description

Bialaphos is a tripeptide antibiotic that is used in transformation experiments of many species of plants that make use of the bar gene for selection. In corn, it is more effective than glufosinate. In wheat, bialaphos was the most reliable selection criteria used to identify bar transformed plants.

Once introduced into a nonresistant plant cell, bialaphos is hydrolyzed and converted to phosphinothricin through the phosphinothricin acetyl transferase enzyme. Phosphinothricin is toxic within plants, causing ammonia to build up, which inhibits glutamine synthetase.

This broad-spectrum herbicide also has effectiveness against gram-negative and gram-positive bacteria, as well as certain fungal plant pathogens.

Product Specifications

Catalog ID B0178
CAS # 71048-99-2
MW 345.26 g/mol
Grade MOLECULAR BIOLOGY GRADE
Storage/Handling Store desiccated at -20°C.
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B0178-100 100 mg $ 133.00
B0178-250 250 mg $ 316.00
B0178-500 500 mg $ 580.00

Chlorimuron ethyl (Sulfonylurea)

Catalog ID Size Pricing
C-905-10 10 mg $ 111.00

Description

Chlorimuron ethyl is a sulfonylurea organic compound used as an insulin enhancing compound and also for herbicide. Promotion of insulin release by chlorimuron ethyl occurs by inhibiting ATP-sensitive potassium channels, which depolarizes the cell membrane of β-islet pancreatic cells. Depolarization is followed by a large influx of calcium that signals the cell to exocytose insulin vesicles.

Chlorimuron ethyl has also been used to induce plant death by inhibiting acetolactate synthase (ALS). The enzyme ALS synthesized branched chain amino acids, such as valine and leucine, which are integral to forming key enzymes in photosynthesis and aerobic respiration. Scarcity of these vital amino acids leads to reactive oxygen species generation and diminished DNA synthesis.

Product Specifications

Catalog ID C-905
CAS # 90982-32-4
MW 414.82 g/mol
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C-905-10 10 mg $ 111.00

Chlorsulfuron

Catalog ID Size Pricing
C-935-100 100 mg $ 64.00

Description

Chlorsulfuron is a sulfonylurea herbicide of broad-leaf plants that inhibits biosynthetic pathways of amino acids. Being a water soluble herbicide, chlorsulfuron has been studied to understand soil biodegradation rates and investigate new measuring techniques in order to prevent hazardous herbicide accumulation. It has also been used to examine cross-resistance and resistance inheritance in a variety of plants such as Sisymbrium orientale.

Chlorsulfuron specifically blocks biosynthesis of the amino acids valine and isoleucine, by inhibiting acetolactate synthase. This enzyme is the first enzyme that is specific to the synthesis of branched chain amino acids. Chlorsufluron is a noncompetitive enzyme that binds to the allosteric site and is specific to the enzyme itself and equally well to the enzyme-substrate complex.

Product Specifications

Catalog ID C-935
CAS # 64902-72-3
MW 357.77 g/mol
UN Number 3077
Item Class 9
Group Number III
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C-935-100 100 mg $ 64.00

Dicamba

Catalog ID Size Pricing
D-760-1 1 g $ 201.00

Description

Dicamba is benzoic acid derivative that is used as an herbicide of broad-leaf plants. It has specifically been used for plant selection and studying herbicide resistance. Dicamba is a synthetic form of the hormone auxin, a plant growth hormone. By impersonating auxin, dicamba promotes unregulated cell growth which will exhaust a plants resources and ultimately result in cell death.

Product Specifications

Catalog ID D-760
CAS # 1918-00-9
MW 221.04 g/mol
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D-760-1 1 g $ 201.00

Imazapyr

Catalog ID Size Pricing
I-205-100 100 mg $ 44.00
I-205-1 1 g $ 317.00

Description

Imazapyr is imidazolinone family herbicide that has been used to research herbicidal resistances and biochemical pathways in an array of plants. This compound has been shown to uncompetitively inhibit acetolactate synthase (ALS) which catalyzes the production of the amino acids valine, leucine and isoleucine. Loss of these specific amino acids depletes physiologically important proteins and enzymes, eventually resulting in cell death.

Product Specifications

Catalog ID I-205
CAS # 81334-34-1
MW 261.28 g/mol
Storage/Handling Store desiccated at 4°C.
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I-205-100 100 mg $ 44.00
I-205-1 1 g $ 317.00

Phosphinothricin

Catalog ID Size Pricing
P-165-250 250 mg $ 99.00
P-165-1 1 g $ 281.00
P-165-5 5 g $ 1,059.00

Description

Phosphinothricin is a broad-spectrum herbicide that acts as a competitive inhibitor of glutamine synthetase.

Glutamine synthetase plays an important role in plant nitrogen metabolism. Its actions lead to the formation of glutamine; however, when inhibited by phosphinothricin, a rapid accumulation of ammonia along with reduction in glutamine occurs within plants.

This herbicide makes an ideal agent for the selection of transformed plants. Plant resistance to phosphinothricin is conferred through the bar gene, and due to the fast degradation of phosphinothricin in soil and in water, it presents a low risk for environmental contamination.

Product Specifications

Catalog ID P-165
CAS # 77182-82-2
MW 198.16 g/mol
Storage/Handling Store desiccated at -20°C.
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P-165-250 250 mg $ 99.00
P-165-1 1 g $ 281.00
P-165-5 5 g $ 1,059.00

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