Quinolones

Quinolones are a family of synthetic, broad-spectrum antibiotics. Fluoroquinolone antibiotics target bacterial DNA gyrase, an enzyme that reduces DNA strain during replication. Because DNA gyrase is required during DNA replication, subsequent DNA synthesis and cell division is inhibited. Fluoroquinolones can enter cells easily via porins and therefore, are often used to treat intracellular pathogens such as Legionella pneumophila and Mycoplasma pneumoniae. Gold Biotechnology quinolones include ciproflaxin, enrofloxacin, flumequine, sparfloxacin and more.
Showing 1-18 of 18 items.

Ciprofloxacin

Catalog ID Size Pricing
C-860-5 5 g $ 31.00   $ 25.00
C-860-10 10 g $ 59.00   $ 48.00
C-860-25 25 g $ 105.00   $ 84.00
C-860-100 100 g $ 317.00   $ 254.00

Description

Ciprofloxacin is a second generation fluoroquinolone antibiotic targeting a broad-spectrum of bacteria and mycoplasma. It is nalidixic acid analog and has few known resistant strains. Ciprofloxacin is also effective as a plant fungicide and is sparingly soluble in water. GoldBio also offers a water soluble version, Ciprofloxacin HCl, for easier use in specific applications.

Product Specifications

Catalog ID C-860
CAS # 85721-33-1
MW 331.34 g/mol
Grade MOLECULAR BIOLOGY GRADE
Storage/Handling Store at 4°C.
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C-860-5 5 g $ 31.00
$ 25.00
C-860-10 10 g $ 59.00
$ 48.00
C-860-25 25 g $ 84.00
C-860-100 100 g $ 317.00
$ 254.00

Ciprofloxacin HCl

Catalog ID Size Pricing
C-861-5 5 g $ 21.00   $ 17.00
C-861-10 10 g $ 38.00   $ 31.00
C-861-25 25 g $ 69.00   $ 56.00
C-861-100 100 g $ 239.00   $ 192.00

Description

Ciprofloxacin is a second generation fluoroquinolone antibiotic targeting a broad-spectrum of bacteria and mycoplasma. It is nalidixic acid analog and has few known resistant strains. Ciprofloxacin is also effective as a plant fungicide. Ciprofloxacin HCl is freely soluble in water. GoldBio also offers Ciprofloxacin, a purer form of the antibiotic which does not contain HCl, but is sparingly soluble in water.

Product Specifications

Catalog ID C-861
CAS # 86393-32-0
MW 385.82 g/mol
Grade MOLECULAR BIOLOGY GRADE
Storage/Handling Store at 4°C.
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C-861-5 5 g $ 21.00
$ 17.00
C-861-10 10 g $ 38.00
$ 31.00
C-861-25 25 g $ 69.00
$ 56.00
C-861-100 100 g $ 239.00
$ 192.00

Difloxacin HCl

Catalog ID Size Pricing
D-440-1 1 g $ 92.00
D-440-5 5 g $ 378.00

Description

Difloxacin is a fluoroquinolone antibiotic targeting gram-negative and gram-positive bacteria as well as Mycobacterium tuberculosis. Additionally, it has shown efficacy against Chlamydia trachomatis. Difloxacin has been used to study the effects of magnesium supplementation on quinolone-induced damage in animal models. Difloxacin HCl is freely soluble in aqueous solution.

Product Specifications

Catalog ID D-440
CAS # 91296-86-5
MW 435.85 g/mol
Grade MOLECULAR BIOLOGY GRADE
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D-440-1 1 g $ 92.00
D-440-5 5 g $ 378.00

Enoxacin

Catalog ID Size Pricing
E-900-1 1 g $ 63.00

Description

Enoxacin is a fluoroquinolone antibiotic compound that is markedly effective against gram negative bacteria. It has been used to study fluoroquinolone cross-resistence in Escehria coli, Pseudomonas aeruginosa and Staphylococcus aureus. Enoxacin is structurally related to nalidixic acid and inhibits DNA gyrase in bacteria.

Fluoroquinolones are a group of broad-spectrum antibiotics that inhibit DNA synthesis. These antibiotics prevent unwinding of double-stranded DNA by binding DNA gyrase or DNA topoisomerase. By preventing the formation of single-stranded DNA, fluoroquinolones inhibit bacterial replication.

Antibiotics are often used in clinical in vitro tests known as antimicrobial susceptibility tests or ASTs to determine their efficacy against certain bacterial species. They are tested against gram-negative and gram-positive bacteria using panels, discs, and MIC strips by medical microbiologists. ASTs decrease the risk of using an antibiotic against bacteria exhibiting resistance to it, and the results are used in clinical settings to determine which antibiotic(s) to prescribe for various infections.

Product Specifications

Catalog ID E-900
CAS # 74011-58-8
MW 347.36 g/mol
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E-900-1 1 g $ 63.00

Enrofloxacin

Catalog ID Size Pricing
E-230-5 5 g $ 105.00
E-230-25 25 g $ 428.00

Description

Enrofloxacin is a fluoroquinolone antibiotic targeting gram-positive and gram-negative bacteria as well as some Mycoplasma species. It has been useful in researching resistance to quinolones in Salmonella enterica, Mycoplasma gallisepticum, and E. coli.

Product Specifications

Catalog ID E-230
CAS # 93106-60-6
MW 359.39 g/mol
Grade MOLECULAR BIOLOGY GRADE
Storage/Handling Store at 4°C.
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E-230-5 5 g $ 105.00
E-230-25 25 g $ 428.00

Enrofloxacin HCl

Catalog ID Size Pricing
E-231-100 100 mg $ 105.00
E-231-500 500 mg $ 413.00
E-231-1 1 g $ 696.00

Description

Enrofloxacin is a fluoroquinolone antibiotic targeting gram-positive and gram-negative bacteria as well as some Mycoplasma species. It has been useful in researching resistance to quinolones in Salmonella enterica, Mycoplasma gallisepticum, and E. coli. It is freely soluble in aqueous solution.

Product Specifications

Catalog ID E-231
CAS # 112732-17-9
MW 395.86 g/mol
Grade MOLECULAR BIOLOGY GRADE
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E-231-100 100 mg $ 105.00
E-231-500 500 mg $ 413.00
E-231-1 1 g $ 696.00

Flumequine

Catalog ID Size Pricing
F-510-5 5 g $ 128.00
F-510-10 10 g $ 228.00

Description

Flumequine is a first generation fluoroquinolone antibiotic targeting gram-negative bacteria, especially those responsible for enteric infections in animals. It is freely soluble in alkali hydroxide solutions of dilute concentrations.

Product Specifications

Catalog ID F-510
CAS # 42835-25-6
MW 261.25 g/mol
Grade MOLECULAR BIOLOGY GRADE
Storage/Handling Store at room temperature.
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F-510-5 5 g $ 128.00
F-510-10 10 g $ 228.00

Gatifloxacin

Catalog ID Size Pricing
G-410-1 1 g $ 62.00
G-410-5 5 g $ 266.00

Description

Gatifloxacin is a fourth generation fluoroquinolone antibiotic with a significant degree of activity towards gram-negative bacteria and enhanced activity toward gram-positive bacteria. It is also potent in vivo against Staphylococcus aureus, Clostridium and many other anaerobic bacteria. Gatifloxacin has also exhibited strong bactericidal efficiency in penicillin resistant and sensitive Streptococcus pneumoniae and S. aureus.

Fluoroquinolones are a group of broad-spectrum antibiotics that inhibit DNA synthesis. These antibiotics prevent unwinding of double-stranded DNA by binding DNA gyrase or DNA topoisomerase. By preventing the formation of single-stranded DNA, fluoroquinolones inhibit bacterial replication.

Product Specifications

Catalog ID G-410
CAS # 112811-59-3
MW 401.41 g/mol
Storage/Handling Store desiccated at -20°C.
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G-410-1 1 g $ 62.00
G-410-5 5 g $ 266.00

Levofloxacin

Catalog ID Size Pricing
L-110-5 5 g $ 57.00

Description

Levofloxacin is a fluoroquinolone antibiotic that is an optical S-(-) isomer of ofloxacin. In vitro susceptibility tests show a large degree of activity towards gram-positive and gram-negative bacteria with moderate anaerobic activity.

Fluoroquinolones are a group of broad-spectrum antibiotics that inhibit DNA synthesis. These antibiotics prevent unwinding of double-stranded DNA by binding DNA gyrase or DNA topoisomerase. By preventing the formation of single-stranded DNA, fluoroquinolones inhibit bacterial replication.

Antibiotics are often used in clinical in vitro tests known as antimicrobial susceptibility tests or ASTs to determine their efficacy against certain bacterial species. They are tested against gram-negative and gram-positive bacteria using panels, discs, and MIC strips by medical microbiologists. ASTs decrease the risk of using an antibiotic against bacteria exhibiting resistance to it, and the results are used in clinical settings to determine which antibiotic(s) to prescribe for various infections.

Product Specifications

Catalog ID L-110
CAS # 100986-85-4
MW 379.39 g/mol
Storage/Handling Store at 4°C.
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L-110-5 5 g $ 57.00

Marbofloxacin

Catalog ID Size Pricing
M-810-100 100 mg $ 61.00
M-810-500 500 mg $ 83.00
M-810-1 1 g $ 159.00

Description

Marbofloxacin is a third generation fluoroquinolone antibiotic used to target Pseudomonades and Staphylococci species. It also targets a variety of other gram-positive and gram-negative bacteria. It is freely soluble in aqueous solution.

Product Specifications

Catalog ID M-810
CAS # 115550-35-1
MW 362.36 g/mol
Grade MOLECULAR BIOLOGY GRADE
Storage/Handling Store at 4°C.
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M-810-100 100 mg $ 61.00
M-810-500 500 mg $ 83.00
M-810-1 1 g $ 159.00

Moxifloxacin HCl

Catalog ID Size Pricing
M-940-100 100 mg $ 111.00
M-940-500 500 mg $ 445.00

Description

Moxifloxacin is a broad-spectrum fourth generation fluoroquinolone antibiotic. It targets both gram-negative and gram-positive bacteria. In addition, it has been shown to combat methicillin-susceptible Staphylococci species as well as penicillin-resistant and penicillin-susceptible Pneumococci and Streptococci species.

Product Specifications

Catalog ID M-940
CAS # 186826-86-8
MW 437.89 g/mol
Grade MOLECULAR BIOLOGY GRADE
Storage/Handling Store at 4°C.
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M-940-100 100 mg $ 111.00
M-940-500 500 mg $ 445.00

Nalidixic acid

Catalog ID Size Pricing
N-015-100 100 g $ 57.00
N-015-250 250 g $ 86.00
N-015-500 500 g $ 160.00
N-015-1 1 kg $ 309.00

Description

Nalidixic acid is a naphthyridone antibiotic that is similar in structure and mechanism to quinolones and is effective against both gram-positive and gram-negative bacteria. It acts as a bacteriostatic in lower concentrations but can be bacteriocidal at higher concentrations. Nalidixic acid indirectly inhibits proteins synthesis by binding DNA and interfering with enzymes involved in DNA replication and transcription and is commonly used in the treatment of urinary tract infections.

Product Specifications

Catalog ID N-015
CAS # 389-08-2
MW 232.24 g/mol
Grade MOLECULAR BIOLOGY GRADE
Storage/Handling Store at 4°C.
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N-015-100 100 g $ 57.00
N-015-250 250 g $ 86.00
N-015-500 500 g $ 160.00
N-015-1 1 kg $ 309.00

Norfloxacin

Catalog ID Size Pricing
N-700-5 5 g $ 66.00
N-700-10 10 g $ 116.00

Description

Norfloxacin is a first generation fluoroquinolone antibiotic targeting primarily gram-negative bacteria responsible for causing urinary tract infections. It is a derivative of pefloxacin.

Product Specifications

Catalog ID N-700
CAS # 70458-96-7
MW 319.33 g/mol
Grade MOLECULAR BIOLOGY GRADE
Storage/Handling Store at 4°C.
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N-700-5 5 g $ 66.00
N-700-10 10 g $ 116.00

Ofloxacin

Catalog ID Size Pricing
O-200-1 1 g $ 41.00
O-200-10 10 g $ 176.00

Description

Ofloxacin is a second generation fluoroquinolone antibiotic targeting gram-negative and gram-positive bacteria. It is an analog of nalidixic acid.

Product Specifications

Catalog ID O-200
CAS # 82419-36-1
MW 361.37 g/mol
Grade MOLECULAR BIOLOGY GRADE
Storage/Handling Store at 4°C. Protect from light.
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O-200-1 1 g $ 41.00
O-200-10 10 g $ 176.00

Oxolinic Acid

Catalog ID Size Pricing
O-300-5 5 g $ 101.00
O-300-25 25 g $ 344.00

Description

Oxolinic acid is a synthetic quinolone antibiotic targeting gram-negative bacteria, especially those responsible for causing urinary tract infections. It has also been reported to be effective against Burkholderia glumae, a bacteria causing grain rot, sheath rot, seedling rot, and bacterial panicle blight. It has been useful in studying transmissible resistance mechanisms of E. coli and S. enterica. It can be used to isolate Gardnerella vaginalis and as a dopamine reuptake inhibitor in neurological research.

Product Specifications

Catalog ID O-300
CAS # 14698-29-4
MW 261.23 g/mol
Grade MOLECULAR BIOLOGY GRADE
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O-300-5 5 g $ 101.00
O-300-25 25 g $ 344.00

Pefloxacin Mesylate Dihydrate

Catalog ID Size Pricing
P-710-10 10 g $ 56.00
P-710-50 50 g $ 222.00

Description

Perfloxacin is a fluoroquinolone antibiotic and is an analog of norfloxacin. It targets gram-negative and gram-positive bacteria as well as several Mycoplasma species. It is commonly used against Gonococcal species and to induce achilles tendon toxicity in rodents.

Product Specifications

Catalog ID P-710
CAS # 149676-40-4
MW 465.49 g/mol
Grade MOLECULAR BIOLOGY GRADE
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P-710-10 10 g $ 56.00
P-710-50 50 g $ 222.00

Sarafloxacin HCl Trihydrate

Catalog ID Size Pricing
S-300-5 5 g $ 49.00
S-300-25 25 g $ 165.00

Description

Sarafloxacin is a broad-spectrum fluoroquinolone antibiotic effective against a variety of gram-negative and gram-positive organisms, especially Mycobacterium tuberculosis. Sarafloxacin HCl Trihydrate is water soluble.

Product Specifications

Catalog ID S-300
CAS # 91296-87-6 (anhydrous)
MW 475.87 g/mol
Grade MOLECULAR BIOLOGY GRADE
Storage/Handling Store at 4°C.
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S-300-5 5 g $ 49.00
S-300-25 25 g $ 165.00

Sparfloxacin

Catalog ID Size Pricing
S-460-10 10 g $ 127.00

Description

Sparfloxacin is a broad-spectrum fluoroquinolone antibiotic targeting gram-negative and gram-positive bacteria as well as Mycoplasma species. It is especially effective against bacteria responsible for respiratory tract infections such as pneumonia. Sparfloxacin also displays photosensitizing effects.

Product Specifications

Catalog ID S-460
CAS # 110871-86-8
MW 392.40 g/mol
Grade MOLECULAR BIOLOGY GRADE
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S-460-10 10 g $ 127.00

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