{"title":"All Recombinant Proteins \u0026 Cytokines","description":"","products":[{"product_id":"shh-murine","title":"SHH, Murine","description":"\u003cp\u003e \u003cstrong\u003eGoldBio growth factors are manufactured for RESEARCH USE ONLY and cannot be sold for human consumption!\u003c\/strong\u003e \u003c\/p\u003e \u003cp\u003e Recombinant  Murine Sonic HedgeHog (SHH) \u003cbr\u003e rMuSHH \u003cbr\u003e Hhg1 \u003cbr\u003e Hxl3 \u003c\/p\u003e \u003cp\u003e Members of the Hedgehog (Hh) family are highly conserved proteins that are widely represented throughout the animal kingdom. The three known mammalian Hh proteins, Sonic (Shh), Desert (Dhh) and Indian (Ihh), are structurally related and share a high degree of amino acid sequence identity. Each Hh protein has a unique expression pattern and distinct biological role within its respective region of secretion. All Hh proteins use the same signaling pathway and can substitute for each other in experimental systems. Shh has been found to have a critical role in development, acting as a morphogen in the patterning of limbs, brain structure, facial structure, lungs, spinal cord, thalamus and the teeth. Shh has been shown to attract commissural axons in the developing spinal cord by attracting or repelling retinal ganglion cell (RGC) axons depending on concentration. Murine SHH is frequently coexpressed with BMP2, BMP4, and BMP6. \u003c\/p\u003e \u003cp\u003e Sterile Filtered White lyophilized powder. Purified and tested for use in cell culture. \u003c\/p\u003e \u003cp\u003e Source:\u003cem\u003e Escherichia coli\u003c\/em\u003e \u003c\/p\u003e \u003cp\u003e MW: ~19.8 kDa (176  amino acids) \u003c\/p\u003e \u003cp\u003e Purity: \u0026gt;95% by SDS-PAGE  and HPLC analyses \u003c\/p\u003e \u003cp\u003e Biological Activity: Fully biologically  active when compared to standard. The ED\u003csub\u003e50\u003c\/sub\u003e as determined by  inducing alkaline phosphatase production of murine C3H10T1\/2 cells is 0.5-1.0 μg\/ml. \u003c\/p\u003e \u003cp\u003e Storage\/Handling: Store desiccated at  -20°C. \u003c\/p\u003e \u003cp\u003e MGD: \u003ca href=\"http:\/\/www.informatics.jax.org\/marker\/MGI:98297\"\u003e98297\u003c\/a\u003e \u003c\/p\u003e \u003cp\u003e NOT FOR HUMAN USE! \u003c\/p\u003e \u003cp\u003e \u003cstrong\u003eAdditional resources for this protein may be found at:\u003c\/strong\u003e \u003cbr\u003e \u003ca href=\"http:\/\/www.omim.org\/entry\/600725\"\u003eOMIM\u003c\/a\u003e\u003cbr\u003e \u003c\/p\u003e","brand":"GoldBio","offers":[{"title":"5 μg","offer_id":44854832037945,"sku":"6310-19-5","price":195.0,"currency_code":"USD","in_stock":true},{"title":"100 μg","offer_id":44854832070713,"sku":"6310-19-100","price":1194.0,"currency_code":"USD","in_stock":true},{"title":"500 μg","offer_id":44854832103481,"sku":"6310-19-500","price":2464.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0718\/5235\/9737\/files\/6310-19_20rMuSHH.png?v=1757447715"},{"product_id":"shh-human","title":"SHH, Human","description":"\u003cp\u003e\u003cstrong\u003eGoldBio growth factors are manufactured for RESEARCH USE ONLY and cannot be sold for human consumption!\u003c\/strong\u003e \u003c\/p\u003e \u003cp\u003eRecombinant Human Sonic HedgeHog\u003cbr\u003e rHuShh\u003cbr\u003e Hhg2 \u003c\/p\u003e \u003cp\u003eMembers of the Hedgehog (Hh) family are highly conserved proteins that are widely represented throughout the animal kingdom. The three known mammalian Hh proteins, Sonic (Shh), Desert (Dhh) and Indian (Ihh), are structurally related and share a high degree of amino acid sequence identity. Each Hh protein has a unique expression pattern and distinct biological role within its respective region of secretion.  All Hh proteins use the same signaling pathway and can substitute for each other in experimental systems. Shh has been found to have a critical role in development, acting as a morphogen in the patterning of limbs, brain structure, spinal cord, thalamus and the teeth.  Shh has been shown to attract commissural axons in the developing spinal cord by attracting or repelling retinal ganglion cell (RGC) axons depending on concentration. \u003c\/p\u003e \u003cp\u003eFormulation: Sterile filtered white  lyophilized powder. Purified and tested for use in cell culture. \u003c\/p\u003e \u003cp\u003eSequence: IVIGPGRGFG  KRRHPKKLTP LAYKQFIPNV AEKTLGASGR YEGKISRNSE RFKELTPNYN PDIIFKDEEN TGADRLMTQR  CKDKLNALAI SVMNQWPGVK LRVTEGWDED GHHSEESLHY EGRAVDITTS DRDRSKYGML ARLAVEAGFD  WVYYESKAHI HCSVKAENSV AAKSGG \u003c\/p\u003e \u003cp\u003eMW: ~20.0 kDa (176 amino acid) \u003c\/p\u003e \u003cp\u003ePurity: \u0026gt;98 % by  SDS-PAGE and HPLC analyses. \u003c\/p\u003e \u003cp\u003eBiological Activity: Fully biologically   active when compared to standard. The ED\u003csub\u003e50\u003c\/sub\u003e as determined by   inducing alkaline phosphatase production of murine C3H\/10T1\/2 cells is less   than1.0 μg\/ml, corresponding to a   specific activity of \u0026gt;1.0 × 10\u003csup\u003e3\u003c\/sup\u003e IU\/mg. \u003c\/p\u003e \u003cp\u003eAccession Number: \u003ca href=\"https:\/\/www.uniprot.org\/uniprot\/Q15465\" target=\"_blank\"\u003e\u003cu\u003eQ15465\u003c\/u\u003e\u003c\/a\u003e \u003c\/p\u003e \u003cp\u003eHGNC ID: \u003ca href=\"https:\/\/www.genenames.org\/data\/gene-symbol-report\/#!\/hgnc_id\/HGNC:10848\" target=\"_blank\"\u003e\u003cu\u003e10848\u003c\/u\u003e\u003c\/a\u003e \u003c\/p\u003e \u003cp\u003eSource: \u003cem\u003eEscherichia coli\u003c\/em\u003e \u003cbr\u003e \u003c\/p\u003e \u003cp\u003e\u003ci\u003e\u003c\/i\u003e \u003c\/p\u003e \u003cp\u003eStorage\/Handling: This lyophilized  preparation is stable at 2-8°C, but should be kept at -20°C for long term  storage. The reconstituted sample can be apportioned into working aliquots and  stored at -80°C for up to 6 months.  Avoid repeated freeze\/thaw cycles. \u003c\/p\u003e \u003cp\u003eReconstitution: The sample should  be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute  in a siliconized tube using PBS that contains a 0.1% BSA to a concentration of  0.1-1.0 mg\/mL. Reconstituted solutions are stable for up to one week at 2-8°C.  Stock solutions should be aliquoted and stored at -80°C. Further dilutions  should be made in appropriate buffered solutions. \u003c\/p\u003e \u003cp\u003eAdditional resources for this product may be found at: \u003c\/p\u003e \u003cp\u003e\u003ca href=\"https:\/\/omim.org\/entry\/600725?search=shh\u0026amp;highlight=shh\" target=\"_blank\"\u003e\u003cu\u003eOMIM\u003c\/u\u003e\u003c\/a\u003e \u003c\/p\u003e \u003cp\u003eNOT FOR HUMAN USE! \u003c\/p\u003e \u003cp\u003e\u003cstrong\u003e\u003c\/strong\u003e\u003ci\u003e\u003c\/i\u003e\u003cu\u003e\u003c\/u\u003e\u003csub\u003e\u003c\/sub\u003e\u003csup\u003e\u003c\/sup\u003e\u003cdel\u003e\u003c\/del\u003e\u003cbr\u003e \u003c\/p\u003e","brand":"GoldBio","offers":[{"title":"5 μg","offer_id":44854832169017,"sku":"6110-19-5","price":195.0,"currency_code":"USD","in_stock":true},{"title":"100 μg","offer_id":44854832201785,"sku":"6110-19-100","price":1194.0,"currency_code":"USD","in_stock":true},{"title":"500 μg","offer_id":44854832234553,"sku":"6110-19-500","price":2464.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0718\/5235\/9737\/files\/6110-19_20rHuSHH.png?v=1757447719"},{"product_id":"ccl24-rat","title":"CCL24, Rat","description":"\u003cp\u003e \u003cstrong\u003eGoldBio growth factors are manufactured for RESEARCH USE ONLY and cannot be sold for human consumption!\u003c\/strong\u003e \u003c\/p\u003e \u003cp\u003e Recombinant  Rat Chemokine (C-C motif) Ligand 24 (CCL24) \u003cbr\u003e Myeloid Progenitor  Inhibitory Factor 2 (MPIF2, MPIF-2) \u003cbr\u003e Small  Inducible Cytokine Subfamily A Member 24 (SCYA24) \u003cbr\u003e Eotaxin 2 \u003c\/p\u003e \u003cp\u003e Rat CCL24 is a chemokine containing four conserved cysteine residues, two of which are adjacent. It is expressed by activated monocytes and activated T lymphocytes. CCL24 is expressed in jejunum and spleen constitutively and is upregulated by allergen challenge and IL4 overexpression. CCL24 is chemotactic for resting T lymphocytes and eosinophils and is a suppressor of HPP-CFC myeloid progenitor cells. It causes a transient rise in intracellular calcium levels in eosinophils and is involved in a variety of eosinophilic inflammatory diseases. CCL24 is a ligand for CCR3. \u003c\/p\u003e \u003cp\u003e Sterile Filtered White lyophilized powder. Purified and tested for use in cell culture. \u003c\/p\u003e \u003cp\u003e Source:\u003cem\u003e Escherichia coli\u003c\/em\u003e \u003c\/p\u003e \u003cp\u003e MW: ~10.5 kDa (98  amino acids) \u003c\/p\u003e \u003cp\u003e Purity: \u0026gt;96% by SDS-PAGE  and HPLC analyses \u003c\/p\u003e \u003cp\u003e Biological Activity: Fully biologically  active when compared to standard. The biologically active determined by a  chemotaxis bioassay using human peripheral blood eosinophils is in a  concentration of 50-250 ng\/ml. \u003c\/p\u003e \u003cp\u003e Storage\/Handling: Store desiccated at  -20°C. \u003c\/p\u003e \u003cp\u003e RGD: \u003ca href=\"http:\/\/rgd.mcw.edu\/rgdweb\/report\/gene\/main.html?id=1310245\"\u003e1310245\u003c\/a\u003e \u003c\/p\u003e \u003cp\u003e NOT FOR HUMAN USE! \u003c\/p\u003e \u003cp\u003e \u003cstrong\u003eAdditional resources for this protein may be found at:\u003c\/strong\u003e \u003cbr\u003e \u003ca href=\"http:\/\/www.omim.org\/entry\/602495\"\u003eOMIM\u003c\/a\u003e \u003cbr\u003e \u003c\/p\u003e","brand":"GoldBio","offers":[{"title":"5 μg","offer_id":44854832988217,"sku":"2540-24-5","price":195.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0718\/5235\/9737\/files\/2540-24_20structure.jpg?v=1757447737"},{"product_id":"mip2-virus","title":"MIP2, Virus","description":"\u003cp\u003e \u003cstrong\u003eGoldBio growth factors are manufactured for RESEARCH USE ONLY and cannot be sold for human consumption!\u003c\/strong\u003e\u003c\/p\u003e\u003cp\u003e Recombinant  Macrophage Inflammatory Protein 2 (vMIP2, vMIP-II) \u003cbr\u003e Viral  Chemokine (C-C motif) Ligand 2 (vCCL2, VCCL-2) \u003cbr\u003e Interleukin  8-like CC Chemokine \u003cbr\u003e K4\u003c\/p\u003e\u003cp\u003e Viral MIP2 is a viral homolog of the human chemokines. It is encoded by the \u003cem\u003eK4\u003c\/em\u003e gene in human herpesvirus-8. Viral MIP2 binds with high affinity to most chemokine receptors as an antagonist. It binds to CCR3 and CCR8 as an agonist. VMIP2 is chemotactic for Th2 cells, eosinophils, and monocytes. It plays a role in promoting Kaposi’s sarcoma, possibly through chemotaxis of monocytes or by angiogenesis. VMIP2 also diminishes host immunity by upregulating IL10 and can block infection of type 1 HIV strains by binding to host chemokine receptors.\u003c\/p\u003e\u003cp\u003e Sterile Filtered White lyophilized powder. Purified and tested for use in cell culture.\u003c\/p\u003e\u003cp\u003e Source:\u003cem\u003e Escherichia coli\u003c\/em\u003e\u003c\/p\u003e\u003cp\u003e MW: ~8.0 kDa (70 amino  acids)\u003c\/p\u003e\u003cp\u003e Purity: \u0026gt;97% by SDS-PAGE  and HPLC analyses\u003c\/p\u003e\u003cp\u003e Biological Activity: Fully biologically  active when compared to standard. The specific activity is determined by the inhibitory  effect on monocyte migration response to human MIP-1 alpha using a concentration  range of 1-10 µg\/ml of viral MIP-2 will inhibit 25 ng\/ml of human MIP-1  alpha.\u003c\/p\u003e\u003cp\u003e Storage\/Handling: Store desiccated at  -20°C.\u003c\/p\u003e\u003cp\u003e NCBI: \u003ca href=\"http:\/\/www.ncbi.nlm.nih.gov\/gene\/4961514\"\u003e4961514\u003c\/a\u003e\u003c\/p\u003e\u003cp\u003e NOT FOR HUMAN USE!\u003c\/p\u003e\u003cp\u003e \u003cstrong\u003eAdditional resources for this protein may be found at:\u003c\/strong\u003e \u003cbr\u003e\u003ca href=\"http:\/\/www.uniprot.org\/uniprot\/Q98157\"\u003eUniProt\u003c\/a\u003e\u003c\/p\u003e","brand":"GoldBio","offers":[{"title":"10 μg","offer_id":44854833020985,"sku":"2910-02-10","price":195.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0718\/5235\/9737\/files\/2910-02_20structure.jpg?v=1757447737"},{"product_id":"ccl28-rat","title":"CCL28, Rat","description":"\u003cp\u003e \u003cstrong\u003eGoldBio growth factors are manufactured for RESEARCH USE ONLY and cannot be sold for human consumption!\u003c\/strong\u003e \u003c\/p\u003e \u003cp\u003e Recombinant  Rat Chemokine (C-C motif) Ligand 28 (CCL28) \u003cbr\u003e Mucosae-Associated  Epithelial Chemokine (MEC) \u003cbr\u003e Small Inducible  Cytokine Subfamily A Member 28 (SCYA28) \u003c\/p\u003e \u003cp\u003e Rat CCL28 is a chemokine containing six conserved cysteine residues, two of which are adjacent. It is expressed constitutively in epithelial cells at mucosal sites, such as salivary glands and the colon, and expression is upregulated by proinflammatory stimuli such as IL1 and n-butyrate. CCL28 is chemotactic for resting T-cells, eosinophils, and IgA antibody-secreting cells (ASCs). It is important for regulating IgA ASC accumulation in mammary glands and consequently the transfer of IgA antibodies from mother to infant. CCL28 displays antimicrobial activity in low-salt conditions against Candida albicans, gram-negative, and gram positive bacteria. CCL28 is a ligand for CCR10 and CCR3. \u003c\/p\u003e \u003cp\u003e Sterile Filtered White lyophilized powder. Purified and tested for use in cell culture. \u003c\/p\u003e \u003cp\u003e Source: \u003cem\u003eEscherichia coli\u003c\/em\u003e \u003c\/p\u003e \u003cp\u003e MW: ~13.1 kDa (116  amino acids) \u003c\/p\u003e \u003cp\u003e Purity: \u0026gt;96% by SDS-PAGE  and HPLC analyses \u003c\/p\u003e \u003cp\u003e Biological Activity: Fully biologically  active when compared to standard. The biological activity determined by a  chemotaxis bioassay using human lymphocytes is in a concentration range of 5-50  ng\/ml. \u003c\/p\u003e \u003cp\u003e Storage\/Handling: Store desiccated at  -20°C. \u003c\/p\u003e \u003cp\u003e RGD: \u003ca href=\"http:\/\/rgd.mcw.edu\/rgdweb\/report\/gene\/main.html?id=619937\"\u003e619937\u003c\/a\u003e \u003c\/p\u003e \u003cp\u003e NOT FOR HUMAN USE! \u003c\/p\u003e \u003cp\u003e \u003cstrong\u003eAdditional resources for this protein may be found at:\u003c\/strong\u003e \u003cbr\u003e \u003ca href=\"http:\/\/www.omim.org\/entry\/605240\"\u003eOMIM\u003c\/a\u003e \u003cbr\u003e \u003c\/p\u003e","brand":"GoldBio","offers":[{"title":"5 μg","offer_id":44854833053753,"sku":"2540-28-5","price":195.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0718\/5235\/9737\/files\/Default_No_Image_Bottle_png.png?v=1757612830"},{"product_id":"ccl22-rat","title":"CCL22, Rat","description":"\u003cp\u003e \u003cstrong\u003eGoldBio growth factors are manufactured for RESEARCH USE ONLY and cannot be sold for human consumption!\u003c\/strong\u003e \u003c\/p\u003e \u003cp\u003e Recombinant  Rat Chemokine (C-C motif) Ligand 22 (CCL22) \u003cbr\u003e Stimulated T  Cell Chemotactic Protein 1 (STCP-1) \u003cbr\u003e Small  Inducible Cytokine Subfamily A Member 22 (SCYA22) \u003cbr\u003e Macrophage-Derived  Chemokine (MDC) \u003c\/p\u003e \u003cp\u003e Rat CCL22 is a chemokine containing four conserved cysteine residues, two of which are adjacent. It is expressed in activated splenic B-cells, macrophages, and dendritic cells. Expression of CCL22 is induced by IL4, IL13, and IFNG and inhibited by IL10. Increased expression CCL22 has also been observed after incubation of mast cells with TNF-alpha or IgE. CCL22 is chemotactic for chronically activated T-cells and plays a role in trafficking activated T cells. It also plays a role in migration and survival of cells expressing FOXP3. CCL22 is a ligand for CCR4. \u003c\/p\u003e \u003cp\u003e Sterile Filtered White lyophilized powder. Purified and tested for use in cell culture. \u003c\/p\u003e \u003cp\u003e Source: \u003cem\u003eEscherichia coli\u003c\/em\u003e \u003c\/p\u003e \u003cp\u003e MW: ~7.9 kDa (68 amino  acids) \u003c\/p\u003e \u003cp\u003e Purity: \u0026gt;96% by SDS-PAGE  and HPLC analyses \u003c\/p\u003e \u003cp\u003e Biological Activity: Fully biologically  active when compared to standard. The biological activity determined by a  chemotaxis bioassay using human T-lymphocytes is in a concentration of 10-100  ng\/ml. \u003c\/p\u003e \u003cp\u003e Storage\/Handling: Store desiccated at  -20°C. \u003c\/p\u003e \u003cp\u003e RGD: \u003ca href=\"http:\/\/rgd.mcw.edu\/rgdweb\/report\/gene\/main.html?id=619933\"\u003e619933\u003c\/a\u003e \u003c\/p\u003e \u003cp\u003e NOT FOR HUMAN USE! \u003c\/p\u003e \u003cp\u003e \u003cstrong\u003eAdditional resources for this protein may be found at:\u003c\/strong\u003e \u003cbr\u003e \u003ca href=\"http:\/\/www.omim.org\/entry\/602957\"\u003eOMIM\u003c\/a\u003e \u003cbr\u003e \u003c\/p\u003e","brand":"GoldBio","offers":[{"title":"5 μg","offer_id":44854833086521,"sku":"2540-22-5","price":195.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0718\/5235\/9737\/files\/Default_No_Image_Bottle_png.png?v=1757612830"},{"product_id":"ccl7-rat","title":"CCL7, Rat","description":"\u003cp\u003e \u003cstrong\u003eGoldBio growth factors are manufactured for RESEARCH USE ONLY and cannot be sold for human consumption!\u003c\/strong\u003e \u003c\/p\u003e \u003cp\u003e Recombinant  Rat Chemokine (C-C motif) Ligand 7 (CCL7) \u003cbr\u003e Monocyte  Chemoattractant Protein 3 (MCP3, MCP-3) \u003cbr\u003e Small Inducible  Cytokine Subfamily A Member 7 (SCYA7) \u003cbr\u003e Fibroblast-Inducible  Cytokine (FIC) \u003cbr\u003e Mast Cell  Activation-Related Chemokine (MARC) \u003c\/p\u003e \u003cp\u003e Rat CCL7 is a chemokine containing four conserved cysteine residues, of which the first two are adjacent. It was first isolated from murine mast cells stimulated by IgE interacting with an antigen and is expressed and secreted by T cells, monocytes, macrophages, and a variety of tumor cell lines. Expression is induced by IFNG and inhibited by IL13. It is chemotactic for monocytes, macrophages, eosinophils, and NK cells and regulates protease secretion by macrophages which may contribute to metastasis of cancer cells. CCL7 also promotes neuritogenesis in midbrain dopamine neuron cultures. CCL7 is a ligand primarily for CCR2, as well as CCR1, CCR3, CCR10, and ACKR2 (D6). \u003c\/p\u003e \u003cp\u003e Sterile Filtered White lyophilized powder. Purified and tested for use in cell culture. \u003c\/p\u003e \u003cp\u003e Source: \u003cem\u003eEscherichia coli\u003c\/em\u003e \u003c\/p\u003e \u003cp\u003e MW: ~8.5 kDa (74 amino  acids) \u003c\/p\u003e \u003cp\u003e Purity: \u0026gt;95% by SDS-PAGE  and HPLC analyses \u003c\/p\u003e \u003cp\u003e Biological Activity: Fully biologically  active when compared to standard. The biological activity determined by a  chemotaxis bioassay using human monocytes is in a concentration of 10-100  ng\/ml. \u003c\/p\u003e \u003cp\u003e Storage\/Handling: Store desiccated at  -20°C. \u003c\/p\u003e \u003cp\u003e RGD: \u003ca href=\"http:\/\/rgd.mcw.edu\/rgdweb\/report\/gene\/main.html?id=1359152\"\u003e1359152\u003c\/a\u003e \u003c\/p\u003e \u003cp\u003e NOT FOR HUMAN USE! \u003c\/p\u003e \u003cp\u003e \u003cstrong\u003eAdditional resources for this protein may be found at:\u003c\/strong\u003e \u003cbr\u003e \u003ca href=\"http:\/\/www.omim.org\/entry\/158106\"\u003eOMIM\u003c\/a\u003e \u003cbr\u003e \u003c\/p\u003e","brand":"GoldBio","offers":[{"title":"10 μg","offer_id":44854833152057,"sku":"2540-07-10","price":278.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0718\/5235\/9737\/files\/Default_No_Image_Bottle_png.png?v=1757612830"},{"product_id":"ccl11-rat","title":"CCL11, Rat","description":"\u003cp\u003e \u003cstrong\u003eGoldBio growth factors are manufactured for RESEARCH USE ONLY and cannot be sold for human consumption!\u003c\/strong\u003e \u003c\/p\u003e \u003cp\u003e Recombinant  Rat Chemokine (C-C motif) Ligand 11 (CCL11) \u003cbr\u003e Eotaxin,  Eotaxin 1 \u003cbr\u003e Small  Inducible Cytokine Subfamily A Member 11 (SCYA11) \u003c\/p\u003e \u003cp\u003e Rat CCL11 is a chemokine containing four conserved cysteine residues, of which the first two are adjacent. It is expressed in fibroblasts, epithelial cells, smooth muscle cells, and dendritic cells. Expression of CCL11 is upregulated by several proinflammatory cytokines, including IL1A and TNFA, and is inhibited by IFNG. CCL11 is strongly and selectively chemotactic and activating for eosinophils and is involved in a variety of eosinophilic inflammatory diseases. It also plays a role in angiogenesis and tumor growth. CCL11 is a ligand primarily for CCR3, but also CCR1, CCR2, CCR5, and ACKR2 (D6). \u003c\/p\u003e \u003cp\u003e Sterile Filtered White lyophilized powder. Purified and tested for use in cell culture. \u003c\/p\u003e \u003cp\u003e Source:\u003cem\u003e Escherichia coli\u003c\/em\u003e \u003c\/p\u003e \u003cp\u003e MW: ~8.4 kDa (74 amino  acids) \u003c\/p\u003e \u003cp\u003e Purity: \u0026gt;96% by SDS-PAGE  and HPLC analyses \u003c\/p\u003e \u003cp\u003e Biological Activity: Fully biologically  active when compared to standard. The biological activity determined by a  chemotaxis bioassay using purified eosinophils is in a concentration of 100-1000  ng\/ml. \u003c\/p\u003e \u003cp\u003e Storage\/Handling: Store desiccated at  -20°C. \u003c\/p\u003e \u003cp\u003e RGD: \u003ca href=\"http:\/\/rgd.mcw.edu\/rgdweb\/report\/gene\/main.html?id=3644\"\u003e3644\u003c\/a\u003e \u003c\/p\u003e \u003cp\u003e NOT FOR HUMAN USE! \u003c\/p\u003e \u003cp\u003e \u003cstrong\u003eAdditional resources for this protein may be found at:\u003c\/strong\u003e \u003cbr\u003e \u003ca href=\"http:\/\/www.omim.org\/entry\/601156\"\u003eOMIM\u003c\/a\u003e \u003cbr\u003e \u003c\/p\u003e","brand":"GoldBio","offers":[{"title":"5 μg","offer_id":44854833184825,"sku":"2540-11-5","price":195.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0718\/5235\/9737\/files\/2540-11_20structure.jpg?v=1757447741"},{"product_id":"ccl17-rat","title":"CCL17, Rat","description":"\u003cp\u003e \u003cstrong\u003eGoldBio growth factors are manufactured for RESEARCH USE ONLY and cannot be sold for human consumption!\u003c\/strong\u003e \u003c\/p\u003e \u003cp\u003e Recombinant  Rat Chemokine (C-C motif) Ligand 17 (CCL17) \u003cbr\u003e Thymus and  Activation Regulated Chemokine (TARC) \u003cbr\u003e Small  Inducible Cytokine Subfamily A Member 17 (SCYA17) \u003c\/p\u003e \u003cp\u003e Rat CCL17 is a chemokine containing four conserved cysteine residues, two of which are adjacent. It is expressed constitutively in the thymus and lymph nodes and transiently in peripheral blood mononuclear cells that have been induced by phytogemagglutinin. CCL17 is chemotactic for T-cells and plays a role in T-cell development, trafficking, and activation. It promotes atherosclerosis by regulating homeostasis of regulatory T-cells, thereby limiting their expansion. CCL17 is a ligand for CCR4, CCR8, and the erythrocyte receptor ACKR1. \u003c\/p\u003e \u003cp\u003e Sterile Filtered White lyophilized powder. Purified and tested for use in cell culture. \u003c\/p\u003e \u003cp\u003e Source: \u003cem\u003eEscherichia coli\u003c\/em\u003e \u003c\/p\u003e \u003cp\u003e MW: ~8.1 kDa (70 amino  acids) \u003c\/p\u003e \u003cp\u003e Purity: \u0026gt;97% by SDS-PAGE  and HPLC analyses \u003c\/p\u003e \u003cp\u003e Biological Activity: Fully biologically  active when compared to standard. The biological activity determined by a  chemotaxis bioassay using human T-lymphocytes is in a concentration of 1-10  ng\/ml. \u003c\/p\u003e \u003cp\u003e Storage\/Handling: Store desiccated at  -20°C. \u003c\/p\u003e \u003cp\u003e RGD: \u003ca href=\"http:\/\/rgd.mcw.edu\/rgdweb\/report\/gene\/main.html?id=619924\"\u003e619924\u003c\/a\u003e \u003c\/p\u003e \u003cp\u003e NOT FOR HUMAN USE! \u003c\/p\u003e \u003cp\u003e \u003cstrong\u003eAdditional resources for this protein may be found at:\u003c\/strong\u003e \u003cbr\u003e \u003ca href=\"http:\/\/www.omim.org\/entry\/601520\"\u003eOMIM\u003c\/a\u003e \u003cbr\u003e \u003c\/p\u003e","brand":"GoldBio","offers":[{"title":"5 μg","offer_id":44854833217593,"sku":"2540-17-5","price":195.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0718\/5235\/9737\/files\/2540-17_20structure.jpg?v=1757447743"},{"product_id":"ccl6-rat","title":"CCL6, Rat","description":"\u003cp\u003e \u003cstrong\u003eGoldBio growth factors are manufactured for RESEARCH USE ONLY and cannot be sold for human consumption!\u003c\/strong\u003e \u003c\/p\u003e \u003cp\u003e Recombinant  Rat Chemokine (C-C motif) Ligand 6 (CCL6) \u003cbr\u003e Small  Inducible Cytokine Subfamily A Member 6 (SCYA6) \u003cbr\u003e Macrophage  Inflammatory Protein-Related Protein 1 (MRP1, MRP-1) \u003cbr\u003e C10 \u003c\/p\u003e \u003cp\u003e Rat CCL6 is a chemokine containing four conserved cysteine residues, two of which are adjacent. It is expressed primarily in microglia and other macrophages, as well as myelopoietic bone marrow cells. Upregulation of expression of CCL6 has been observed after stimulation with IFNG, CSF1, CSF2, IL3, and IL4. CCL6 expression is also stimulated by IL-13 and is required for IL-13 stimulation of other chemokines. CCL6 is chemotactic for macrophages and lymphocytes and acts as a ligand primarily for CCR1. CCL6 has only been observed in rodents thus far; rat CCL6 is most homologous to human CCL14, CCL15, and CCL23. \u003c\/p\u003e \u003cp\u003e Sterile Filtered White lyophilized powder. Purified and tested for use in cell culture. \u003c\/p\u003e \u003cp\u003e Source: \u003cem\u003eEscherichia coli\u003c\/em\u003e \u003c\/p\u003e \u003cp\u003e MW: ~10.4 kDa (94  amino acids) \u003c\/p\u003e \u003cp\u003e Purity: \u0026gt;97% by SDS-PAGE  and HPLC analyses \u003c\/p\u003e \u003cp\u003e Biological Activity: Fully biologically  active when compared to standard. The biologically active determined by a  chemotaxis bioassay using human CCR1 transfected murine BaF3 cells is in a  concentration range of 10-100 ng\/ml. \u003c\/p\u003e \u003cp\u003e Storage\/Handling: Store desiccated at  -20°C. \u003c\/p\u003e \u003cp\u003e RGD: \u003ca href=\"http:\/\/rgd.mcw.edu\/rgdweb\/report\/gene\/main.html?id=1303200\"\u003e1303200\u003c\/a\u003e \u003c\/p\u003e \u003cp\u003e NOT FOR HUMAN USE! \u003c\/p\u003e \u003cp\u003e \u003cstrong\u003e\u003cbr\u003e\u003c\/strong\u003e\u003ca href=\"http:\/\/www.copewithcytokines.de\/cope.cgi?key=C10\"\u003e\u003c\/a\u003e \u003c\/p\u003e","brand":"GoldBio","offers":[{"title":"10 μg","offer_id":44854833250361,"sku":"2540-06-10","price":278.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0718\/5235\/9737\/files\/Default_No_Image_Bottle_png.png?v=1757612830"},{"product_id":"ccl4-rat","title":"CCL4, Rat","description":"\u003cp\u003e \u003cstrong\u003eGoldBio growth factors are manufactured for RESEARCH USE ONLY and cannot be sold for human consumption!\u003c\/strong\u003e \u003c\/p\u003e \u003cp\u003e Recombinant  Rat Chemokine (C-C motif) Ligand 4 (CCL4) \u003cbr\u003e Macrophage  Inflammatory Protein 1, Beta (MIP1B, MIP1B1) \u003cbr\u003e Small  Inducible Cytokine Subfamily A Member 4 (SCYA4) \u003cbr\u003e Immune  Activation 2 (ACT2, ACT-2) \u003c\/p\u003e \u003cp\u003e Rat CCL4 is a chemokine containing four conserved cysteine residues, of which the first two are adjacent. It is expressed and secreted by T-cells, B-cells, monocytes, and various tumor cells lines. Expression of CCL4 is induced by IL2 and mitogens, such as phytohemmagglutinin, LPS, and the peptidoglycan wall of \u003cem\u003eS. aureus\u003c\/em\u003e and expression is inhibited by glucocorticoids, TGF-beta, and cyclosporin A. CCL4 is an HIV-suppressive factor and may contribute to amyloid deposition in Alzheimer disease. It also binds to HSV-1 virions and generates pores in the envelope of HSV-1. CCL4 is a ligand for CCR1, CCR3, CCR5, CCR8, and ACKR2 (D6). \u003c\/p\u003e \u003cp\u003e Sterile Filtered White lyophilized powder. Purified and tested for use in cell culture. \u003c\/p\u003e \u003cp\u003e Source: \u003cem\u003eEscherichia coli\u003c\/em\u003e \u003c\/p\u003e \u003cp\u003e MW: ~7.8 kDa (69 amino  acids) \u003c\/p\u003e \u003cp\u003e Purity: \u0026gt;95% by SDS-PAGE  and HPLC analyses \u003c\/p\u003e \u003cp\u003e Biological Activity: Fully biologically  active when compared to standard. The biological activity determined by a  chemotaxis bioassay using human peripheral blood monocytes is in a concentration  of 10-1000 ng\/ml. \u003c\/p\u003e \u003cp\u003e Storage\/Handling: Store desiccated at  -20°C. \u003c\/p\u003e \u003cp\u003e RGD: \u003ca href=\"http:\/\/rgd.mcw.edu\/rgdweb\/report\/gene\/main.html?id=620441\"\u003e620441\u003c\/a\u003e \u003c\/p\u003e \u003cp\u003e NOT FOR HUMAN USE! \u003c\/p\u003e \u003cp\u003e \u003cstrong\u003eAdditional resources for this protein may be found at:\u003c\/strong\u003e \u003cbr\u003e \u003ca href=\"http:\/\/www.omim.org\/entry\/182284\"\u003eOMIM\u003c\/a\u003e \u003cbr\u003e \u003c\/p\u003e","brand":"GoldBio","offers":[{"title":"5 μg","offer_id":44854833283129,"sku":"2540-04-5","price":195.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0718\/5235\/9737\/files\/2540-04_20structure.jpg?v=1757447745"},{"product_id":"cx3cl1-rat","title":"CX3CL1, Rat","description":"\u003cp\u003e \u003cstrong\u003eGoldBio growth factors are manufactured for RESEARCH USE ONLY and cannot be sold for human consumption!\u003c\/strong\u003e \u003c\/p\u003e \u003cp\u003e Recombinant  Rat Chemokine (C-X3-C motif) Ligand 1 (CX3CL1) \u003cbr\u003e Fractalkine \u003cbr\u003e Small  Inducible Cytokine Subfamily D Member 1 (SCYD1) \u003cbr\u003e ATP-Binding  Cassette, Subfamily D Member 3 (ABCD-3) \u003cbr\u003e Neurotactin  (NTN) \u003c\/p\u003e \u003cp\u003eRat CX3CL1 is a chemokine that is unlike most chemokines because it contains the C-X-X-X-C motif. It is expressed by neurons, endothelial cells, follicular dendritic cells, and some lymphocytes. Expression of CX3CL1 is induced by activation of the transcription factor NFKB1 through IFNG, IL1B, TNF, or LPS. CX3CL1 is chemotactic for T-cells and monocytes and plays a role in angiogenesis, as well as regulation of leukocyte traffic at the endothelium. CX3CL1 expressed by neurons suppress microglia in order to protect neurons from damage caused by reactive molecules expressed by microglia. CX3CL1 is a ligand for CX3CR1 as well as virus-encoded receptors M3 and US28. \u003c\/p\u003e \u003cp\u003e Sterile Filtered White lyophilized powder. Purified and tested for use in cell culture. \u003c\/p\u003e \u003cp\u003e Source: \u003cem\u003eEscherichia coli\u003c\/em\u003e \u003c\/p\u003e \u003cp\u003e MW: ~8.8 kDa (76 amino  acids) \u003c\/p\u003e \u003cp\u003e Purity: \u0026gt;95% by SDS-PAGE  and HPLC analyses \u003c\/p\u003e \u003cp\u003e Biological Activity: Fully biologically  active when compared to standard. The biological activity determined by a  chemotaxis bioassay using human monocytes is in a concentration of 5-10  ng\/ml. \u003c\/p\u003e \u003cp\u003e Storage\/Handling: Store desiccated at  -20°C. \u003c\/p\u003e \u003cp\u003e RGD: \u003ca href=\"http:\/\/rgd.mcw.edu\/rgdweb\/report\/gene\/main.html?id=620458\"\u003e620458\u003c\/a\u003e \u003c\/p\u003e \u003cp\u003e NOT FOR HUMAN USE! \u003c\/p\u003e \u003cp\u003e \u003cstrong\u003eAdditional resources for this protein may be found at:\u003c\/strong\u003e \u003cbr\u003e \u003ca href=\"http:\/\/www.omim.org\/entry\/601880\"\u003eOMIM\u003c\/a\u003e \u003cbr\u003e \u003c\/p\u003e","brand":"GoldBio","offers":[{"title":"5 μg","offer_id":44854833315897,"sku":"2530-01-5","price":195.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0718\/5235\/9737\/files\/2530-01_20structure.jpg?v=1757447746"},{"product_id":"ccl3-rat","title":"CCL3, Rat","description":"\u003cp\u003e \u003cstrong\u003eGoldBio growth factors are manufactured for RESEARCH USE ONLY and cannot be sold for human consumption!\u003c\/strong\u003e \u003c\/p\u003e \u003cp\u003e Recombinant  Rat Chemokine (C-C motif) Ligand 3 (CCL3) \u003cbr\u003e Monocyte  Chemoattractant Protein 1, Alpha (MCP1α, MCP-1α) \u003cbr\u003e Small  Inducible Cytokine Subfamily A Member 3 (SCYA3) \u003cbr\u003e LD78-Alpha \u003cbr\u003e Macrophage  Inflammatory Protein 1, Alpha (MIP1A) \u003cbr\u003e G0\/G1  Switch Gene 19-1 (GOS-19-1) \u003c\/p\u003e \u003cp\u003e Rat CCL3 is a chemokine containing four conserved cysteine residues, of which the first two are adjacent. It is expressed by T-cells, B-cells, macrophages, and various tumor cells lines and has been identified as a G0\/G1 switch gene in various cells. CCL3 is the primary stimulator of TNF secretion and is chemotactic for polymorphonuclear leukocytes. CCL3 induces superoxide production by neutrophils, plays an inhibitory role in hematopoiesis, and displays inhibitory activity against strains of HIV-1, HIV-2, and SIV. CCL3 is a ligand for CCR1, CCR4, and the HIV-1 coreceptor CCR5. Activation of CCR5 through CCL3 activates a G-protein pathway through GNAI2 and a tyrosine phosphorylation through JAK2. \u003c\/p\u003e \u003cp\u003e Sterile Filtered White lyophilized powder. Purified and tested for use in cell culture. \u003c\/p\u003e \u003cp\u003e Source:\u003cem\u003e Escherichia coli\u003c\/em\u003e \u003c\/p\u003e \u003cp\u003e MW: ~7.9 kDa (69 amino  acids) \u003c\/p\u003e \u003cp\u003e Purity: \u0026gt;98% by SDS-PAGE  and HPLC analyses \u003c\/p\u003e \u003cp\u003e Biological Activity: Fully biologically  active when compared to standard. The biological activity determined by a chemotaxis  bioassay using human blood monocytes is in a concentration range of 10-100  ng\/ml. \u003c\/p\u003e \u003cp\u003e Storage\/Handling: Store desiccated at  -20°C. \u003c\/p\u003e \u003cp\u003e RGD: \u003ca href=\"http:\/\/rgd.mcw.edu\/rgdweb\/report\/gene\/main.html?id=3647\"\u003e3647\u003c\/a\u003e \u003c\/p\u003e \u003cp\u003e NOT FOR HUMAN USE! \u003c\/p\u003e \u003cp\u003e \u003cstrong\u003eAdditional resources for this protein may be found at:\u003c\/strong\u003e \u003cbr\u003e \u003ca href=\"http:\/\/www.omim.org\/entry\/182283\"\u003eOMIM\u003c\/a\u003e \u003cbr\u003e \u003c\/p\u003e","brand":"GoldBio","offers":[{"title":"5 μg","offer_id":44854833348665,"sku":"2540-03-5","price":195.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0718\/5235\/9737\/files\/2540-03_20structure.jpg?v=1757447747"},{"product_id":"cxcl17-rat","title":"CXCL17, Rat","description":"\u003cp\u003e \u003cstrong\u003eGoldBio growth factors are manufactured for RESEARCH USE ONLY and cannot be sold for human consumption!\u003c\/strong\u003e \u003c\/p\u003e \u003cp\u003e Recombinant  Rat Chemokine (C-X-C motif) Ligand 17 (CXCL17) \u003cbr\u003e VEGF  Coregulated Chemokine 1 (VCC1) \u003cbr\u003e Small Inducible  Cytokine Subfamily B Member 17 (SCYB17) \u003cbr\u003e Dendritic  Cell and Monocyte Chemokine-like Protein (DMC) \u003c\/p\u003e \u003cp\u003e Rat CXCL17 is a CXC chemokine appearing to lack the ELR motif, yet functioning as a chemokine that does contain the ELR motif as it plays a role in angiogenesis and is chemotactic for neutrophils. It also plays a role in regulation of mucosal inflammatory responses and is chemotactic for macrophages, monocytes, dendritic cells, and immature myeloid-derived cells. CXCL17 expression has been observed in several tissues, but appears to be restricted to mucosal sites such as the digestive system, lung airways, the urethra, and different sites of the female reproductive system. CXCL17 is a ligand for the receptor GPR35. \u003c\/p\u003e \u003cp\u003e Sterile Filtered White lyophilized powder. Purified and tested for use in cell culture. \u003c\/p\u003e \u003cp\u003e Source: \u003cem\u003eEscherichia coli\u003c\/em\u003e \u003c\/p\u003e \u003cp\u003e MW: ~11.5 kDa (97  amino acids) \u003c\/p\u003e \u003cp\u003e Purity: \u0026gt;97% by SDS-PAGE  and HPLC analyses \u003c\/p\u003e \u003cp\u003e Biological Activity: Fully biologically  active when compared to standard. The ED\u003csub\u003e50\u003c\/sub\u003e as determined by its ability to induce VEGF  expression using murine endothelial cells is less than 5 μg\/ml,  corresponding to a specific activity of \u0026gt;200 IU\/mg. \u003c\/p\u003e \u003cp\u003e Storage\/Handling: Store desiccated at  -20°C. \u003c\/p\u003e \u003cp\u003e RGD: \u003ca href=\"http:\/\/rgd.mcw.edu\/rgdweb\/report\/gene\/main.html?id=1304717\"\u003e1304717\u003c\/a\u003e \u003c\/p\u003e \u003cp\u003e NOT FOR HUMAN USE! \u003c\/p\u003e \u003cp\u003e \u003cstrong\u003eAdditional resources for this protein may be found at:\u003c\/strong\u003e \u003cbr\u003e \u003ca href=\"http:\/\/www.omim.org\/entry\/611387\"\u003eOMIM\u003c\/a\u003e \u003cbr\u003e \u003c\/p\u003e","brand":"GoldBio","offers":[{"title":"10 μg","offer_id":44854833381433,"sku":"2510-17-10","price":278.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0718\/5235\/9737\/files\/Default_No_Image_Bottle_png.png?v=1757612830"},{"product_id":"cxcl12-beta-rat","title":"CXCL12-beta, Rat","description":"\u003cp\u003e \u003cstrong\u003eGoldBio growth factors are manufactured for RESEARCH USE ONLY and cannot be sold for human consumption!\u003c\/strong\u003e \u003c\/p\u003e \u003cp\u003e Recombinant  Rat Chemokine (C-X-C motif) Ligand 12, Beta (CXCL12β) \u003cbr\u003e Stromal  Cell-Derived Factor 1 (SDF1) \u003cbr\u003e Small  Inducible Cytokine Subfamily B Member 12 (SCYB12) \u003cbr\u003e Pre-B Cell  Growth-Stimulating Factor (PBSF) \u003cbr\u003e Thymic Lymphoma  Cell-Stimulating Factor (TLSF) \u003c\/p\u003e \u003cp\u003e Rat CXCL12 is a CXC chemokine lacking the ELR motif. It was first found in bone marrow stromal cells and is expressed in bone marrow stromal cells constitutively as well as a wide variety of cells with the exception of blood cells. Expression of CXCL12 is downregulated in fibroblasts by the phorbol ester TPA and in serum-deprived fibroblasts that have been stimulated by serum. CXCL12 acts as a ligand for CXCR4. It is chemotactic for hematopoietic progenitor cells expressing CD34, mononuclear cells, and cerebellar granule cells. CXCL12 plays a role in lymphopoiesis, myelopoiesis, vascularization of the gastrointestinal tract, and cerebellar development. CXCL12-beta is one of six alternatively spliced isoforms of the CXCL12 gene and is used as the canonical sequence. \u003c\/p\u003e \u003cp\u003e Sterile Filtered White lyophilized powder. Purified and tested for use in cell culture. \u003c\/p\u003e \u003cp\u003e Source:\u003cem\u003e Escherichia coli\u003c\/em\u003e \u003c\/p\u003e \u003cp\u003e MW: ~8.4 kDa (72 amino  acids) \u003c\/p\u003e \u003cp\u003e Purity: \u0026gt;97% by SDS-PAGE  and HPLC analyses \u003c\/p\u003e \u003cp\u003e Biological Activity: Fully biologically  active when compared to standard. The biological activity determined by a  chemotaxis bioassay using human peripheral blood monocytes is in a concentration  range of 100-200 ng\/ml. \u003c\/p\u003e \u003cp\u003e Storage\/Handling: Store desiccated at  -20°C. \u003c\/p\u003e \u003cp\u003e RGD: \u003ca href=\"http:\/\/rgd.mcw.edu\/rgdweb\/report\/gene\/main.html?id=3651\"\u003e3651\u003c\/a\u003e \u003c\/p\u003e \u003cp\u003e NOT FOR HUMAN USE! \u003c\/p\u003e \u003cp\u003e \u003cstrong\u003eAdditional resources for this protein may be found at:\u003c\/strong\u003e \u003cbr\u003e \u003ca href=\"http:\/\/www.omim.org\/entry\/600835\"\u003eOMIM\u003c\/a\u003e \u003cbr\u003e \u003c\/p\u003e","brand":"GoldBio","offers":[{"title":"10 μg","offer_id":44854833414201,"sku":"2510-12B-10","price":278.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0718\/5235\/9737\/files\/2510-12B_20structure.jpg?v=1757447751"},{"product_id":"cxcl14-rat","title":"CXCL14, Rat","description":"\u003cp\u003e \u003cstrong\u003eGoldBio growth factors are manufactured for RESEARCH USE ONLY and cannot be sold for human consumption!\u003c\/strong\u003e \u003c\/p\u003e \u003cp\u003e Recombinant  Rat Chemokine (C-X-C motif) Ligand 14 (CXCL14) \u003cbr\u003e Macrophage  Inflammatory Protein 2, Gamma (MIP2γ, MIP-2-γ) \u003cbr\u003e Small  Inducible Cytokine Subfamily B Member 13 (SCYB13) \u003cbr\u003e B-Cell And  Monocyte-Activating Chemokine (BMAC) \u003cbr\u003e Homolog of  Human Breast and Kidney Cell Chemokine (BRAK) \u003cbr\u003e KS1 \u003c\/p\u003e \u003cp\u003e Rat CXCL14 is a CXC chemokine lacking the ELR motif. It is expressed constitutively in many normal tissues, including brain, lung, ovaries, kidneys, and muscle. CXCL14 is chemotactic for monocytes, macrophages, dendritic cells, activated NK cells, and B cells. It possesses tumor suppressing function in certain cancers possibly due to migrations of NK cells, inhibition of angiogenesis, and reduction of settlement rate of tumor cells. However in contradiction, it can induce tumor growth in other types of cancers. CXCL14 is a natural antagonist for CXCR4 and inhibits CXCL12. \u003c\/p\u003e \u003cp\u003e Sterile Filtered White lyophilized powder. Purified and tested for use in cell culture. \u003c\/p\u003e \u003cp\u003e Source: \u003cem\u003eEscherichia coli\u003c\/em\u003e \u003c\/p\u003e \u003cp\u003e MW: ~9.4 kDa (77 amino  acids) \u003c\/p\u003e \u003cp\u003e Purity: \u0026gt;95% by SDS-PAGE  and HPLC analyses \u003c\/p\u003e \u003cp\u003e Biological Activity: Fully biologically  active when compared to standard. The biological activity determined by a chemotaxis  bioassay using human monocytes is in a concentration range of 1-10 ng\/ml. \u003c\/p\u003e \u003cp\u003e Storage\/Handling: Store desiccated at  -20°C. \u003c\/p\u003e \u003cp\u003e RGD: \u003ca href=\"http:\/\/rgd.mcw.edu\/rgdweb\/report\/gene\/main.html?id=1307406\"\u003e1307406\u003c\/a\u003e \u003c\/p\u003e \u003cp\u003e NOT FOR HUMAN USE! \u003c\/p\u003e \u003cp\u003e \u003cstrong\u003eAdditional resources for this protein may be found at:\u003c\/strong\u003e \u003cbr\u003e \u003ca href=\"http:\/\/www.omim.org\/entry\/604186\"\u003eOMIM\u003c\/a\u003e \u003cbr\u003e \u003c\/p\u003e","brand":"GoldBio","offers":[{"title":"5 μg","offer_id":44854833446969,"sku":"2510-14-5","price":195.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0718\/5235\/9737\/files\/2510-14_20structure.jpg?v=1757447752"},{"product_id":"cxcl12-alpha-rat","title":"CXCL12-alpha, Rat","description":"\u003cp\u003e \u003cstrong\u003eGoldBio growth factors are manufactured for RESEARCH USE ONLY and cannot be sold for human consumption!\u003c\/strong\u003e \u003c\/p\u003e \u003cp\u003e Recombinant  Rat Chemokine (C-X-C motif) Ligand 12, Alpha (CXCL12α) \u003cbr\u003e Stromal  Cell-Derived Factor 1 (SDF1) \u003cbr\u003e Small  Inducible Cytokine Subfamily B Member 12 (SCYB12) \u003cbr\u003e Pre-B Cell  Growth-Stimulating Factor (PBSF) \u003cbr\u003e Thymic Lymphoma  Cell-Stimulating Factor (TLSF) \u003c\/p\u003e \u003cp\u003e Rat CXCL12 is a CXC chemokine lacking the ELR motif. It was first found in bone marrow stromal cells and is expressed in bone marrow stromal cells constitutively as well as a wide variety of cells with the exception of blood cells. Expression of CXCL12 is downregulated in fibroblasts by the phorbol ester TPA and in serum-deprived fibroblasts that have been stimulated by serum. CXCL12 acts as a ligand for CXCR4 and CXCR7. It is chemotactic for hematopoietic progenitor cells expressing CD34, mononuclear cells, and cerebellar granule cells. CXCL12 plays a role in lymphopoiesis, myelopoiesis, vascularization of the gastrointestinal tract, and cerebellar development. CXCL12-alpha is one of six alternatively spliced isoforms of the CXCL12 gene. It is four amino acids shorter at the C-terminus than the canonical sequence, CXCL12-beta. \u003c\/p\u003e \u003cp\u003e Sterile Filtered White lyophilized powder. Purified and tested for use in cell culture. \u003c\/p\u003e \u003cp\u003e Source:\u003cem\u003e Escherichia coli\u003c\/em\u003e \u003c\/p\u003e \u003cp\u003e MW: ~7.9 kDa (68 amino  acids) \u003c\/p\u003e \u003cp\u003e Purity: \u0026gt;97% by SDS-PAGE  and HPLC analyses \u003c\/p\u003e \u003cp\u003e Biological Activity: Fully biologically  active when compared to standard. The biological activity determined by a  chemotaxis bioassay using human peripheral blood monocytes is in a concentration  range of 50-100 ng\/ml. \u003c\/p\u003e \u003cp\u003e Storage\/Handling: Store desiccated at  -20°C. \u003c\/p\u003e \u003cp\u003e RGD: \u003ca href=\"http:\/\/rgd.mcw.edu\/rgdweb\/report\/gene\/main.html?id=3651\"\u003e3651\u003c\/a\u003e \u003c\/p\u003e \u003cp\u003e NOT FOR HUMAN USE! \u003c\/p\u003e \u003cp\u003e \u003cstrong\u003eAdditional resources for this protein may be found at:\u003c\/strong\u003e \u003cbr\u003e \u003ca href=\"http:\/\/www.omim.org\/entry\/600835\"\u003eOMIM\u003c\/a\u003e \u003cbr\u003e \u003c\/p\u003e","brand":"GoldBio","offers":[{"title":"10 μg","offer_id":44854833479737,"sku":"2510-12A-10","price":278.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0718\/5235\/9737\/files\/2510-12A_20structure.jpg?v=1757447752"},{"product_id":"cxcl10-rat","title":"CXCL10, Rat","description":"\u003cp\u003e \u003cstrong\u003eGoldBio growth factors are manufactured for RESEARCH USE ONLY and cannot be sold for human consumption!\u003c\/strong\u003e \u003c\/p\u003e \u003cp\u003e Recombinant  Rat Chemokine (C-X-C motif) Ligand 10 (CXCL10) \u003cbr\u003e Cytokine  Responsive Gene 2 (CRG2) \u003cbr\u003e Small Inducible  Cytokine Subfamily B Member 10 (SCYB10) \u003cbr\u003e Interferon  Gamma Inducible Protein 10, (IP10, INP10) \u003cbr\u003e Mob1, Mob-1 \u003c\/p\u003e \u003cp\u003e Rat CXCL10 is a CXC chemokine lacking the ELR motif. It is expressed in and secreted by monocytes, endothelial cells, fibroblasts, and other cell types transiently after induction by IFNG or constitutively after induction by oncogenic Ras. It is chemotactic for monocytes and T-cell lymphocytes. CXCL10 plays a role in angiostasis, inhibits bone marrow colony formation, and promotes T-cell adhesion to endothelial cells. Knock-out mice have immune system abnormalities, including defective proliferation of T–cells, resulting in increased susceptibility to autoimmune disease and viral infections. It is closely related to CXCL9 and CXCL11, all three of which are ligands for CXCLR3. Increased expression of CXCL10 and CXCR3 is associated with autoimmune myasthenia gravis. \u003c\/p\u003e \u003cp\u003e Sterile Filtered White lyophilized powder. Purified and tested for use in cell culture. \u003c\/p\u003e \u003cp\u003e Source: \u003cem\u003eEscherichia coli\u003c\/em\u003e \u003c\/p\u003e \u003cp\u003e MW: ~8.7 kDa (77 amino  acids) \u003c\/p\u003e \u003cp\u003e Purity: \u0026gt;95% by SDS-PAGE  and HPLC analyses \u003c\/p\u003e \u003cp\u003e Biological Activity: Fully biologically  active when compared to standard. The biological activity determined by a chemotaxis  bioassay using human CXCR3 transfected HEK293 cells is in a concentration  range of 10-50 ng\/ml. \u003c\/p\u003e \u003cp\u003e Storage\/Handling: Store desiccated at  -20°C. \u003c\/p\u003e \u003cp\u003e RGD: \u003ca href=\"http:\/\/rgd.mcw.edu\/rgdweb\/report\/gene\/main.html?id=620209\"\u003e620209\u003c\/a\u003e \u003c\/p\u003e \u003cp\u003e NOT FOR HUMAN USE! \u003c\/p\u003e \u003cp\u003e \u003cstrong\u003eAdditional resources for this protein may be found at:\u003c\/strong\u003e \u003cbr\u003e \u003ca href=\"http:\/\/www.omim.org\/entry\/147310\"\u003eOMIM\u003c\/a\u003e \u003cbr\u003e \u003c\/p\u003e","brand":"GoldBio","offers":[{"title":"5 μg","offer_id":44854833512505,"sku":"2510-10-5","price":195.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0718\/5235\/9737\/files\/2510-10_20structure.jpg?v=1757447752"},{"product_id":"ppbp-cxcl7-rat","title":"PPBP (CXCL7), Rat","description":"\u003cp\u003e \u003cstrong\u003eGoldBio growth factors are manufactured for RESEARCH USE ONLY and cannot be sold for human consumption!\u003c\/strong\u003e \u003c\/p\u003e \u003cp\u003e Recombinant  Rat Pro-Platelet Basic Protein (PPBP) \u003cbr\u003e Chemokine  (C-X-C motif) Ligand 7 (CXCL7) \u003cbr\u003e Neutrophil-Activating  Polypeptide 2 (NAP2, NAP-2) \u003cbr\u003e Small  Inducible Cytokine Subfamily B Member 7 (SCYB7) \u003cbr\u003e Beta-Thomboglobulin  (THBGB1) \u003c\/p\u003e \u003cp\u003e Rat PPBP is an ELR type of CXC chemokine. This recombinant protein is a mature, proteolytically processed form of PPBP that is also known as NAP2. It is expressed in monocytes and macrophages, especially from the lungs, after treatment with bacterial endotoxins and released from the alpha-granules of platelets after their activation. NAP2 is chemotactic for fibroblasts and neutrophils and binds to the receptor CXCR2. It is involved in a variety of cellular processes including mitogenesis, DNA synthesis, extracellular matrix synthesis, glycolysis, and plasminogen activator synthesis. \u003c\/p\u003e \u003cp\u003e Sterile Filtered White lyophilized powder. Purified and tested for use in cell culture. \u003c\/p\u003e \u003cp\u003e Source: \u003cem\u003eEscherichia coli\u003c\/em\u003e \u003c\/p\u003e \u003cp\u003e MW: ~6.8 kDa (62 amino  acids) \u003c\/p\u003e \u003cp\u003e Purity: \u0026gt;97% by SDS-PAGE  and HPLC analyses \u003c\/p\u003e \u003cp\u003e Biological Activity: Fully biologically  active when compared to standard. The biologically active determined by a chemotaxis  bioassay using human CXCR2 transfected murine BaF3 cells is in a concentration  range of 0.1-1.0 ng\/ml. \u003c\/p\u003e \u003cp\u003e Storage\/Handling: Store desiccated at  -20°C. \u003c\/p\u003e \u003cp\u003e RGD: \u003ca href=\"http:\/\/rgd.mcw.edu\/rgdweb\/report\/gene\/main.html?id=70548\"\u003e70548\u003c\/a\u003e \u003c\/p\u003e \u003cp\u003e NOT FOR HUMAN USE! \u003c\/p\u003e \u003cp\u003e \u003cstrong\u003eAdditional resources for this protein may be found at:\u003c\/strong\u003e \u003cbr\u003e \u003ca href=\"http:\/\/www.omim.org\/entry\/121010\"\u003eOMIM\u003c\/a\u003e \u003cbr\u003e \u003c\/p\u003e","brand":"GoldBio","offers":[{"title":"10 μg","offer_id":44854833578041,"sku":"2510-07-10","price":278.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0718\/5235\/9737\/files\/Default_No_Image_Bottle_png.png?v=1757612830"},{"product_id":"cxcl6-cxcl5-rat","title":"CXCL6 (CXCL5), Rat","description":"\u003cp\u003e \u003cstrong\u003eGoldBio growth factors are manufactured for RESEARCH USE ONLY and cannot be sold for human consumption!\u003c\/strong\u003e \u003c\/p\u003e \u003cp\u003e Recombinant  Rat Chemokine (C-X-C motif) Ligand 5 (CXCL6) \u003cbr\u003e Recombinant  Rat Chemokine (C-X-C motif) Ligand 5 (CXCL5) \u003cbr\u003e Lipopolysaccharide  (LPS) Induced CXC Chemokine (LIX) \u003cbr\u003e Small  Inducible Cytokine Subfamily B Member 5 (SCYB5) \u003cbr\u003e Murine Granulocyte  Chemotactic Protein 2 (GCP2, GCP-2) \u003cbr\u003e Alveolar  Macrophage Chemotactic Factor 2 (AMCF2, AMCF-2) \u003cbr\u003e Epithelial-derived  Neutrophil Activating Peptide 78 (ENA78, ENA-78) \u003c\/p\u003e \u003cp\u003e Rat CXCL6 is an ELR type of CXC chemokine. It is expressed in various epithelial cell lines alongside CXCL8 (IL8) and CXCL1 in response to stimulation by IL1 or TNF-alpha. It is down regulated by IFNG. Rat CXCL6 is a ligand for Rat CXCR1. It is a chemoattractant and activator of neutrophils, and plays a role in angiogenesis and inflammation, as well as the metastasis of various cancers. It also blocks insulin signaling by activating the JAK2\/STAT5\/SOCS2 pathway. Rat CXCL6 has also been referred to as rat CXCL5 and is an ortholog of human CXCL5 and CXCL6, as well as murine CXCL5. \u003c\/p\u003e \u003cp\u003e Sterile Filtered White lyophilized powder. Purified and tested for use in cell culture. \u003c\/p\u003e \u003cp\u003e Source:\u003cem\u003e Escherichia coli\u003c\/em\u003e \u003c\/p\u003e \u003cp\u003e MW: ~10.1 kDa (93  amino acids) \u003c\/p\u003e \u003cp\u003e Purity: \u0026gt;97% by SDS-PAGE  and HPLC analyses \u003c\/p\u003e \u003cp\u003e Biological Activity: Fully biologically  active when compared to standard. The biological activity determined by a  chemotaxis bioassay using human peripheral blood neutrophils is in a  concentration of 10-100 ng\/ml. \u003c\/p\u003e \u003cp\u003e Storage\/Handling: Store desiccated at  -20°C. \u003c\/p\u003e \u003cp\u003e RGD: \u003ca href=\"http:\/\/rgd.mcw.edu\/rgdweb\/report\/gene\/main.html?id=708540\"\u003e708540\u003c\/a\u003e \u003c\/p\u003e \u003cp\u003e NOT FOR HUMAN USE! \u003c\/p\u003e \u003cp\u003e \u003cstrong\u003eAdditional resources for this protein may be found at:\u003c\/strong\u003e \u003cbr\u003e \u003ca href=\"http:\/\/www.omim.org\/entry\/600324\"\u003eOMIM\u003c\/a\u003e \u003cbr\u003e \u003c\/p\u003e","brand":"GoldBio","offers":[{"title":"5 μg","offer_id":44854833610809,"sku":"2510-05-5","price":195.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0718\/5235\/9737\/files\/2510-05_20structure.jpg?v=1757447758"},{"product_id":"cxcl3-beta-rat","title":"CXCL3-beta, Rat","description":"\u003cp\u003e \u003cstrong\u003eGoldBio growth factors are manufactured for RESEARCH USE ONLY and cannot be sold for human consumption!\u003c\/strong\u003e \u003c\/p\u003e \u003cp\u003e Recombinant  Rat Chemokine (C-X-C motif) Ligand 3, Beta (CXCL3β) \u003cbr\u003e Melanoma  Growth Stimulating Activity, Gamma (MGSG, MGSA-g) \u003cbr\u003e Macrophage  Inflammatory Protein 2 (MIP2-beta) \u003cbr\u003e Growth Related  Oncogene 3 (GRO3, GRO-gamma) \u003cbr\u003e Cytokine  Induced Neutrophil Chemoattractant 2, Beta (CINC-2B, CINC2B) \u003cbr\u003e Small  Inducible Cytokine Subfamily B Member 3 (SCYB3) \u003cbr\u003e Dendritic Cell  Inflammatory Protein 1 (DCIP1) \u003c\/p\u003e \u003cp\u003e Rat CXCL3 is an ELR type of CXC chemokine. It is secreted by monocytes and macrophages and expressed in a variety of other cells. As a result of alternative splicing, there are two isoforms of rat CXCL3 that differ from each other by three amino acid residues. This recombinant rat CXCL3 isoform is often referred to as CXCL3B or CINC2B. CXCR2 is the receptor that CXCL3 binds. CXCL3 participates in chemotaxis and cell activation of neutrophils. It plays a role in would healing, inflammation, angiogenesis, tumorigenesis, metastasis, and pathogenesis of airway remodeling in asthma. CXCL3 has an effect on the differentiation and function of monocyte-derived dendritic cells, pushing them towards a myeloid-derived suppressor cell (MDSC)-like phenotype. \u003c\/p\u003e \u003cp\u003e Sterile Filtered White lyophilized powder. Purified and tested for use in cell culture. \u003c\/p\u003e \u003cp\u003e Source: \u003cem\u003eEscherichia coli\u003c\/em\u003e \u003c\/p\u003e \u003cp\u003e MW: ~7.6 kDa (68 amino  acids) \u003c\/p\u003e \u003cp\u003e Purity: \u0026gt;96% by SDS-PAGE  and HPLC analyses \u003c\/p\u003e \u003cp\u003e Biological Activity: Fully biologically  active when compared to standard. The biological activity determined by a  chemotaxis bioassay using human CXCR2 transfected murine BaF3 cells is in a  concentration range of 5-50 ng\/ml. \u003c\/p\u003e \u003cp\u003e Storage\/Handling: Store desiccated at  -20°C. \u003c\/p\u003e \u003cp\u003e RGD: \u003ca href=\"http:\/\/rgd.mcw.edu\/rgdweb\/report\/gene\/main.html?id=621812\"\u003e621812\u003c\/a\u003e \u003c\/p\u003e \u003cp\u003e NOT FOR HUMAN USE! \u003c\/p\u003e \u003cp\u003e \u003cstrong\u003eAdditional resources for this protein may be found at:\u003c\/strong\u003e \u003cbr\u003e \u003ca href=\"http:\/\/www.omim.org\/entry\/139111\"\u003eOMIM\u003c\/a\u003e \u003cbr\u003e \u003c\/p\u003e","brand":"GoldBio","offers":[{"title":"10 μg","offer_id":44854833643577,"sku":"2510-03B-10","price":278.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0718\/5235\/9737\/files\/2510-03B_20structure.jpg?v=1757447758"},{"product_id":"cxcl3-alpha-rat","title":"CXCL3-alpha, Rat","description":"\u003cp\u003e \u003cstrong\u003eGoldBio growth factors are manufactured for RESEARCH USE ONLY and cannot be sold for human consumption!\u003c\/strong\u003e \u003c\/p\u003e \u003cp\u003e Recombinant  Rat Chemokine (C-X-C motif) Ligand 3, Alpha (CXCL3α) \u003cbr\u003e Melanoma  Growth Stimulating Activity, Gamma (MGSG, MGSA-g) \u003cbr\u003e Macrophage  Inflammatory Protein 2 (MIP2-beta) \u003cbr\u003e Growth Related  Oncogene 3 (GRO3, GRO-gamma) \u003cbr\u003e Cytokine  Induced Neutrophil Chemoattractant 2, Alpha (CINC-2A, CINC2A) \u003cbr\u003e Small  Inducible Cytokine Subfamily B Member 3 (SCYB3) \u003cbr\u003e Dendritic  Cell Inflammatory Protein 1 (DCIP1) \u003c\/p\u003e \u003cp\u003e Rat CXCL3 is an ELR type of CXC chemokine. It is secreted by monocytes and macrophages and expressed in a variety of other cells. As a result of alternative splicing, there are two isoforms of rat CXCL3 that differ from each other by three amino acid residues. This recombinant rat CXCL3 is the canonical sequence often referred to as CXCL3A or CINC2A. CXCR2 is the receptor that CXCL3 binds. CXCL3 participates in chemotaxis and cell activation of neutrophils. It plays a role in would healing, inflammation, angiogenesis, tumorigenesis, metastasis, and pathogenesis of airway remodeling in asthma. CXCL3 has an effect on the differentiation and function of monocyte-derived dendritic cells, pushing them towards a myeloid-derived suppressor cell (MDSC)-like phenotype. \u003c\/p\u003e \u003cp\u003e Sterile Filtered White lyophilized powder. Purified and tested for use in cell culture. \u003c\/p\u003e \u003cp\u003e Source: \u003cem\u003eEscherichia coli\u003c\/em\u003e \u003c\/p\u003e \u003cp\u003e MW: ~7.8 kDa (69 amino  acids) \u003c\/p\u003e \u003cp\u003e Purity: \u0026gt;96% by SDS-PAGE  and HPLC analyses \u003c\/p\u003e \u003cp\u003e Biological Activity: Fully biologically  active when compared to standard. The biological activity determined by a  chemotaxis bioassay using human CXCR2 transfected murine BaF3 cells is in a  concentration range of 5-50 ng\/ml. \u003c\/p\u003e \u003cp\u003e Storage\/Handling: Store desiccated at  -20°C. \u003c\/p\u003e \u003cp\u003e RGD: \u003ca href=\"http:\/\/rgd.mcw.edu\/rgdweb\/report\/gene\/main.html?id=621812\"\u003e621812\u003c\/a\u003e \u003c\/p\u003e \u003cp\u003e NOT FOR HUMAN USE! \u003c\/p\u003e \u003cp\u003e \u003cstrong\u003eAdditional resources for this protein may be found at:\u003c\/strong\u003e \u003cbr\u003e \u003ca href=\"http:\/\/www.omim.org\/entry\/139111\"\u003eOMIM\u003c\/a\u003e \u003cbr\u003e \u003c\/p\u003e","brand":"GoldBio","offers":[{"title":"10 μg","offer_id":44854833676345,"sku":"2510-03A-10","price":278.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0718\/5235\/9737\/files\/2510-03A_20structure.jpg?v=1757447758"},{"product_id":"cxcl2-rat","title":"CXCL2, Rat","description":"\u003cp\u003e \u003cstrong\u003eGoldBio growth factors are manufactured for RESEARCH USE ONLY and cannot be sold for human consumption!\u003c\/strong\u003e \u003c\/p\u003e \u003cp\u003e Recombinant  Rat Chemokine (C-X-C motif) Ligand 2 \u003cbr\u003e Melanoma  Growth Stimulating Activity, Beta (MGSB, MGSA-b) \u003cbr\u003e Macrophage  Inflammatory Protein 2 (MIP2, MIP2-alpha) \u003cbr\u003e Growth Related  Oncogene 2 (GRO2, GRO-beta) \u003cbr\u003e Cytokine  Induced Neutrophil Chemoattractant 2, Alpha (CINC2-alpha) \u003cbr\u003e Small  Inducible Cytokine Subfamily B Member 2 (SCYB2) \u003c\/p\u003e \u003cp\u003e Rat CXCL2 is an ELR type of CXC chemokine. It is secreted by monocytes and macrophages and expressed in a variety of other cells. Expression of CXCL2 is induced by IL1, TNF, and LPS. CXCL2 participates in chemotaxis of neutrophils, basophils, polymorphonuclear leukocytes, and hematopoietic stem cells. It plays a role in would healing, angiogenesis, tumorigenesis, and pathogenesis of airway remodeling in asthma. CXCL2 exhibits antimicrobial activity against E. coli and S. aureus. CXCL2 is a ligand for CXCR2. CXCL2 shares significant amino acid sequence homology with CXCL1. \u003c\/p\u003e \u003cp\u003e Sterile Filtered White lyophilized powder. Purified and tested for use in cell culture. \u003c\/p\u003e \u003cp\u003e Source:\u003cem\u003e Escherichia coli\u003c\/em\u003e \u003c\/p\u003e \u003cp\u003e MW: ~7.9 kDa (73 amino  acids) \u003c\/p\u003e \u003cp\u003e Purity: \u0026gt;98% by SDS-PAGE  and HPLC analyses \u003c\/p\u003e \u003cp\u003e Biological Activity: Fully biologically  active when compared to standard. The biological activity determined by a  chemotaxis bioassay using rat neutrophils is in a concentration range of 10-100  ng\/ml. \u003c\/p\u003e \u003cp\u003e Storage\/Handling: Store desiccated at  -20°C. \u003c\/p\u003e \u003cp\u003e RGD: \u003ca href=\"http:\/\/rgd.mcw.edu\/rgdweb\/report\/gene\/main.html?id=70069\"\u003e70069\u003c\/a\u003e \u003c\/p\u003e \u003cp\u003e NOT FOR HUMAN USE! \u003c\/p\u003e \u003cp\u003e \u003cstrong\u003eAdditional resources for this protein may be found at:\u003c\/strong\u003e \u003cbr\u003e \u003ca href=\"http:\/\/www.omim.org\/entry\/139110\"\u003eOMIM\u003c\/a\u003e \u003cbr\u003e \u003c\/p\u003e","brand":"GoldBio","offers":[{"title":"5 μg","offer_id":44854833709113,"sku":"2510-02-5","price":195.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0718\/5235\/9737\/files\/2510-02_20structure.jpg?v=1757447760"},{"product_id":"cxcl1-rat","title":"CXCL1, Rat","description":"\u003cp\u003e \u003cstrong\u003eGoldBio growth factors are manufactured for RESEARCH USE ONLY and cannot be sold for human consumption!\u003c\/strong\u003e \u003c\/p\u003e \u003cp\u003e Recombinant  Rat Chemokine (C-X-C motif) Ligand 1 \u003cbr\u003e Melanoma  Growth Stimulating Activity, Alpha (MGSA, MGSA-a) \u003cbr\u003e Fibroblast  Secretory Protein (FSP) \u003cbr\u003e Growth Related  Oncogene 1 (GRO1, GROa) \u003cbr\u003e Cytokine-Induced  Neutrophil Chemoattractant 1 (CINC1, CINC-1) \u003cbr\u003e Small  Inducible Cytokine Subfamily B Member 1 (SCYB1) \u003cbr\u003e Keratinocyte  Chemokine (KC) \u003c\/p\u003e \u003cp\u003e Rat CXCL1 is an ELR type of CXC chemokine. First discovered in mouse fibroblasts, it is secreted by melanoma cells and expressed by neutrophils, monocytes, keratinocytes, macrophages, epithelial cells, and fibroblasts. CXCL1 participates in chemotaxis and cell activation of neutrophils during inflammation. CXCL1 inhibits embryonic oligodendrocyte precursor migration, suggesting a role in spinal cord development. It also plays a role in would healing, angiogenesis, and tumorigenesis. CXCL1 is believed to be the major inflammatory factor in recurrent herpetic stromal keratitis. CXCR2 is the receptor that CXCL1 binds. \u003c\/p\u003e \u003cp\u003e Sterile Filtered White lyophilized powder. Purified and tested for use in cell culture. \u003c\/p\u003e \u003cp\u003e Source: \u003cem\u003eEscherichia coli\u003c\/em\u003e \u003c\/p\u003e \u003cp\u003e MW: ~7.8 kDa (72 amino  acids) \u003c\/p\u003e \u003cp\u003e Purity: \u0026gt;97% by SDS-PAGE  and HPLC analyses \u003c\/p\u003e \u003cp\u003e Biological Activity: Fully biologically  active when compared to standard. The biological activity determined by a chemotaxis  bioassay using human peripheral blood neutrophils is in a concentration range  of 10-100 ng\/ml. \u003c\/p\u003e \u003cp\u003e Storage\/Handling: Store desiccated at  -20°C. \u003c\/p\u003e \u003cp\u003e RGD: \u003ca href=\"http:\/\/rgd.mcw.edu\/rgdweb\/report\/gene\/main.html?id=619869\"\u003e619869\u003c\/a\u003e \u003c\/p\u003e \u003cp\u003e NOT FOR HUMAN USE! \u003c\/p\u003e \u003cp\u003e \u003cstrong\u003eAdditional resources for this protein may be found at:\u003c\/strong\u003e \u003cbr\u003e \u003ca href=\"http:\/\/www.omim.org\/entry\/155730\"\u003eOMIM\u003c\/a\u003e \u003cbr\u003e \u003c\/p\u003e","brand":"GoldBio","offers":[{"title":"5 μg","offer_id":44854833741881,"sku":"2510-01-5","price":195.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0718\/5235\/9737\/files\/2510-01_20structure.jpg?v=1757447764"},{"product_id":"ccl28-murine","title":"CCL28, Murine","description":"\u003cp\u003e \u003cstrong\u003eGoldBio growth factors are manufactured for RESEARCH USE ONLY and cannot be sold for human consumption!\u003c\/strong\u003e \u003c\/p\u003e \u003cp\u003e Recombinant  Murine Chemokine (C-C motif) Ligand 28 (CCL28) \u003cbr\u003e Mucosae-Associated  Eptihelial Chemokine (MEC) \u003cbr\u003e Small  Inducible Cytokine Subfamily A Member 28 (SCYA28) \u003c\/p\u003e \u003cp\u003e Murine CCL28 is a chemokine containing six conserved cysteine residues, two of which are adjacent. It is expressed constitutively in epithelial cells at mucosal sites such as salivary glands and colon and expression is upregulated by proinflammatory stimuli such as IL1 and n-butyrate. CCL28 is chemotactic for resting T-cells, eosinophils, and IgA antibody-secreting cells (ASCs). It is important for regulating IgA ASC accumulation in mammary glands and consequently the transfer of IgA antibodies from mother to infant. Tumor hypoxia causes HIF1α induced expression of CCL28 and subsequent migration of T-cells, promoting tumor tolerance to antigens and angiogenesis. CCL28 is a ligand for CCR10 and CCR3. \u003c\/p\u003e \u003cp\u003e Sterile Filtered White lyophilized powder. Purified and tested for use in cell culture. \u003c\/p\u003e \u003cp\u003e Source: \u003cem\u003eEscherichia coli\u003c\/em\u003e \u003c\/p\u003e \u003cp\u003e MW: ~12.6 kDa (111  amino acids) \u003c\/p\u003e \u003cp\u003e Purity: \u0026gt;97% by SDS-PAGE  and HPLC analyses \u003c\/p\u003e \u003cp\u003e Biological Activity: Fully biologically  active when compared to standard. The biological activity determined by a  chemotaxis bioassay using murine lymphocytes is in a concentration range of  1-10 ng\/ml. \u003c\/p\u003e \u003cp\u003e Storage\/Handling: Store desiccated at  -20°C. \u003c\/p\u003e \u003cp\u003e MGI: \u003ca href=\"http:\/\/www.informatics.jax.org\/marker\/MGI:1861731\"\u003e1861731\u003c\/a\u003e \u003c\/p\u003e \u003cp\u003e NOT FOR HUMAN USE! \u003c\/p\u003e \u003cp\u003e \u003cstrong\u003eAdditional resources for this protein may be found at:\u003c\/strong\u003e \u003cbr\u003e \u003ca href=\"http:\/\/www.omim.org\/entry\/605240\"\u003eOMIM\u003c\/a\u003e \u003cbr\u003e \u003c\/p\u003e","brand":"GoldBio","offers":[{"title":"5 μg","offer_id":44854833774649,"sku":"2340-28-5","price":195.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0718\/5235\/9737\/files\/Default_No_Image_Bottle_png.png?v=1757612830"},{"product_id":"ccl27-murine","title":"CCL27, Murine","description":"\u003cp\u003e \u003cstrong\u003eGoldBio growth factors are manufactured for RESEARCH USE ONLY and cannot be sold for human consumption!\u003c\/strong\u003e \u003c\/p\u003e \u003cp\u003e Recombinant  Murine Chemokine (C-C motif) Ligand 27 (CCL27) \u003cbr\u003e Cutaneous  T-cell Attracting Chemokine (CTACK) \u003cbr\u003e Small  Inducible Cytokine Subfamily A Member 27 (SCYA27) \u003cbr\u003e Interleukin  11 Receptor, Alpha–Locus Chemokine (ILC) \u003cbr\u003e ESkine \u003cbr\u003e PESKY \u003c\/p\u003e \u003cp\u003e CCL27 is a chemokine containing four conserved cysteine residues, two of which are adjacent. As a result of alternative splicing, there are two isoforms of CCL27, each containing a different signal sequence. One variant is expressed in the skin and the placenta and is secreted, while the other is expressed in the testes and brain and targeted to the nucleus to participate in intracrine signaling. This recombinant murine CCL27 is a mature form that lacks a secretion signal sequence or a nuclear targeting sequence. Expression of CCL27 is upregulated by TNF-alpha and IL1B. CCL27 is chemotactic for CLA(+) T-cells and plays a role in T-cell migration in the skin. The intracrine isoform may play a role in cell migration as well by inducing cytoskeletal relaxation. CCL27 is a ligand for CCR10. \u003c\/p\u003e \u003cp\u003e Sterile Filtered White lyophilized powder. Purified and tested for use in cell culture. \u003c\/p\u003e \u003cp\u003e Source: \u003cem\u003eEscherichia coli\u003c\/em\u003e \u003c\/p\u003e \u003cp\u003e MW: ~10.9 kDa (95  amino acids) \u003c\/p\u003e \u003cp\u003e Purity: \u0026gt;98% by SDS-PAGE  and HPLC analyses \u003c\/p\u003e \u003cp\u003e Biological Activity: Fully biologically  active when compared to standard. The biological activity determined by a  chemotaxis bioassay using human peripheral blood lymphocytes is in a concentration  of 10-100 ng\/ml. \u003c\/p\u003e \u003cp\u003e Storage\/Handling: Store desiccated at  -20°C. \u003c\/p\u003e \u003cp\u003e MGI: \u003ca href=\"http:\/\/www.informatics.jax.org\/marker\/MGI:1343459\"\u003e1343459\u003c\/a\u003e \u003c\/p\u003e \u003cp\u003e NOT FOR HUMAN USE! \u003c\/p\u003e \u003cp\u003e \u003cstrong\u003eAdditional resources for this protein may be found at:\u003c\/strong\u003e \u003cbr\u003e \u003ca href=\"http:\/\/www.omim.org\/entry\/604833\"\u003eOMIM\u003c\/a\u003e \u003cbr\u003e \u003c\/p\u003e","brand":"GoldBio","offers":[{"title":"5 μg","offer_id":44854833807417,"sku":"2340-27-5","price":195.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0718\/5235\/9737\/files\/2340-27_20structure.jpg?v=1757447764"},{"product_id":"ccl25-murine","title":"CCL25, Murine","description":"\u003cp\u003e \u003cstrong\u003eGoldBio growth factors are manufactured for RESEARCH USE ONLY and cannot be sold for human consumption!\u003c\/strong\u003e \u003c\/p\u003e \u003cp\u003e Recombinant  Murine Chemokine (C-C motif) Ligand 25 (CCL25) \u003cbr\u003e Thymus-Expressed  Chemokine (TECK) \u003cbr\u003e Small Inducible  Cytokine Subfamily A Member 25 (SCYA25) \u003c\/p\u003e \u003cp\u003e CCL25 is a chemokine containing four conserved cysteine residues, two of which are adjacent. It is expressed primarily by thymic dendritic cells and in small intestine tissue. CCL25 is chemotactic for thymocytes, macrophages, and dendritic cells, as well as IgA antibody-secreting cells and is also a suppressor of myeloid progenitor cells. CCL25 is important for selective homing and retention of T-cells in the small intestine instead of the colon and is possibly involved in T-cell development. It also promotes migration of various types of cancer cells. CCL25 is a ligand for CCR9 and ACKR4. \u003c\/p\u003e \u003cp\u003e Sterile Filtered White lyophilized powder. Purified and tested for use in cell culture. \u003c\/p\u003e \u003cp\u003e Source: \u003cem\u003eEscherichia coli\u003c\/em\u003e \u003c\/p\u003e \u003cp\u003e MW: ~14.1 kDa (121  amino acids) \u003c\/p\u003e \u003cp\u003e Purity: \u0026gt;95% by SDS-PAGE  and HPLC analyses \u003c\/p\u003e \u003cp\u003e Biological Activity: Fully biologically  active when compared to standard. The biological activity determined by a  chemotaxis bioassay using human monocytes is in a concentration of 5-50  ng\/ml. \u003c\/p\u003e \u003cp\u003e Storage\/Handling: Store desiccated at  -20°C. \u003c\/p\u003e \u003cp\u003e MGI: \u003ca href=\"http:\/\/www.informatics.jax.org\/marker\/MGI:1099448\"\u003e1099448\u003c\/a\u003e \u003c\/p\u003e \u003cp\u003e NOT FOR HUMAN USE! \u003c\/p\u003e \u003cp\u003e \u003cstrong\u003eAdditional resources for this protein may be found at:\u003c\/strong\u003e \u003cbr\u003e \u003ca href=\"http:\/\/www.omim.org\/entry\/602565\"\u003eOMIM\u003c\/a\u003e \u003cbr\u003e \u003c\/p\u003e","brand":"GoldBio","offers":[{"title":"5 μg","offer_id":44854833840185,"sku":"2340-25-5","price":195.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0718\/5235\/9737\/files\/Default_No_Image_Bottle_png.png?v=1757612830"},{"product_id":"ccl22-murine","title":"CCL22, Murine","description":"\u003cp\u003e \u003cstrong\u003eGoldBio growth factors are manufactured for RESEARCH USE ONLY and cannot be sold for human consumption!\u003c\/strong\u003e \u003c\/p\u003e \u003cp\u003e Recombinant  Murine Chemokine (C-C motif) Ligand 22 (CCL22) \u003cbr\u003e Stimulated T  Cell Chemotactic Protein 1 (STCP-1) \u003cbr\u003e Small  Inducible Cytokine Subfamily A Member 22 (SCYA22) \u003cbr\u003e Macrophage-Derived  Chemokine (MDC) \u003c\/p\u003e \u003cp\u003e Murine CCL22 is a chemokine containing four conserved cysteine residues, two of which are adjacent. It is expressed in activated splenic B-cells, macrophages, and dendritic cells. Expression of CCL22 is induced by IL4 and IL13 and inhibited by IL10. Increased expression of murine CCL22 has also been observed from bone marrow-derived mast cells after incubation with TNF-alpha or IgE. CCL22 is chemotactic for chronically activated T-cells and plays a role in trafficking activated T cells. It also plays a role in migration and survival of cells expressing FOXP3 in HTLV1 infection. CCL22 is a ligand for CCR4. \u003c\/p\u003e \u003cp\u003e Sterile Filtered White lyophilized powder. Purified and tested for use in cell culture. \u003c\/p\u003e \u003cp\u003e Source: \u003cem\u003eEscherichia coli\u003c\/em\u003e \u003c\/p\u003e \u003cp\u003e MW: ~7.8 kDa (68 amino  acids) \u003c\/p\u003e \u003cp\u003e Purity: \u0026gt;97% by SDS-PAGE  and HPLC analyses \u003c\/p\u003e \u003cp\u003e Biological Activity: Fully biologically  active when compared to standard. The biological activity determined by a  chemotaxis bioassay using human activated lymphocytes is in a concentration of  10-100 ng\/ml. \u003c\/p\u003e \u003cp\u003e Storage\/Handling: Store desiccated at  -20°C. \u003c\/p\u003e \u003cp\u003e MGI: \u003ca href=\"http:\/\/www.informatics.jax.org\/marker\/MGI:1306779\"\u003e1306779\u003c\/a\u003e \u003c\/p\u003e \u003cp\u003e NOT FOR HUMAN USE! \u003c\/p\u003e \u003cp\u003e \u003cstrong\u003eAdditional resources for this protein may be found at:\u003c\/strong\u003e \u003cbr\u003e \u003ca href=\"http:\/\/www.omim.org\/entry\/602957\"\u003eOMIM\u003c\/a\u003e \u003cbr\u003e \u003c\/p\u003e","brand":"GoldBio","offers":[{"title":"5 μg","offer_id":44854834036793,"sku":"2340-22-5","price":195.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0718\/5235\/9737\/files\/Default_No_Image_Bottle_png.png?v=1757612830"},{"product_id":"ccl24-murine","title":"CCL24, Murine","description":"\u003cp\u003e \u003cstrong\u003eGoldBio growth factors are manufactured for RESEARCH USE ONLY and cannot be sold for human consumption!\u003c\/strong\u003e \u003c\/p\u003e \u003cp\u003e Recombinant  Murine Chemokine (C-C motif) Ligand 24 (CCL24) \u003cbr\u003e Myeloid Progenitor  Inhibitory Factor 2 (MPIF2, MPIF-2) \u003cbr\u003e Small  Inducible Cytokine Subfamily A Member 24 (SCYA24) \u003cbr\u003e Eotaxin 2 \u003c\/p\u003e \u003cp\u003e CCL24 is a chemokine containing four conserved cysteine residues, two of which are adjacent. It is expressed by activated monocytes and activated T lymphocytes. Murine CCL24 is expressed in jejunum and spleen constitutively and is upregulated by allergen challenge and IL4 overexpression. CCL24 is chemotactic for resting T lymphocytes and eosinophils and is a suppressor of HPP-CFC myeloid progenitor cells. It causes a transient rise in intracellular calcium levels in eosinophils. CCL24 is a ligand for CCR3. \u003c\/p\u003e \u003cp\u003e Sterile Filtered White lyophilized powder. Purified and tested for use in cell culture. \u003c\/p\u003e \u003cp\u003e Source: \u003cem\u003eEscherichia coli\u003c\/em\u003e \u003c\/p\u003e \u003cp\u003e MW: ~10.3 kDa (93  amino acids) \u003c\/p\u003e \u003cp\u003e Purity: \u0026gt;97% by SDS-PAGE  and HPLC analyses \u003c\/p\u003e \u003cp\u003e Biological Activity: Fully biologically  active when compared to standard. The biological activity determined by a  chemotaxis bioassay using murine lymphocytes is in a concentration of 10-100  ng\/ml. \u003c\/p\u003e \u003cp\u003e Storage\/Handling: Store desiccated at  -20°C. \u003c\/p\u003e \u003cp\u003e MGI: \u003ca href=\"http:\/\/www.informatics.jax.org\/marker\/MGI:1928953\"\u003e1928953\u003c\/a\u003e \u003c\/p\u003e \u003cp\u003e NOT FOR HUMAN USE! \u003c\/p\u003e \u003cp\u003e \u003cstrong\u003eAdditional resources for this protein may be found at:\u003c\/strong\u003e \u003cbr\u003e \u003ca href=\"http:\/\/www.omim.org\/entry\/602495\"\u003eOMIM\u003c\/a\u003e \u003cbr\u003e \u003c\/p\u003e","brand":"GoldBio","offers":[{"title":"5 μg","offer_id":44854834069561,"sku":"2340-24-5","price":195.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0718\/5235\/9737\/files\/2340-24_20structure.jpg?v=1757447769"},{"product_id":"ccl21-murine","title":"CCL21, Murine","description":"\u003cp\u003e \u003cstrong\u003eGoldBio growth factors are manufactured for RESEARCH USE ONLY and cannot be sold for human consumption!\u003c\/strong\u003e \u003c\/p\u003e \u003cp\u003e Recombinant  Murine Chemokine (C-C motif) Ligand 21 (CCL21) \u003cbr\u003e T Cell  Activation 4 (TCA4, TCA-4) \u003cbr\u003e Small Inducible  Cytokine Subfamily A Member 21 (SCYA21) \u003cbr\u003e Secondary  Lymphoid Tissue Chemokine (SLC) \u003cbr\u003e Exodus 2 \u003c\/p\u003e \u003cp\u003e CCL21 is a chemokine containing six conserved cysteine residues, two of which are adjacent. Murine CCL21 is encoded by two to three genes, depending on the strain, each product of which differs by a single amino acid and expression of these genes is regulated differentially. It is expressed in high endothelial venules of lymph nodes, as well as lung, spleen, tonsils, breast stromal cells, and a variety of other cells. Murine CCL21-Leu is expressed predominantly in the lung independent of an inducer. Expression of CCL21 is inhibited by IFNG. It is chemotactic for peripheral blood lymphocytes and plays a major role in initiation and expansion of adaptive immune responses, as well as development of local lymphoid tissue. CCL21 is a ligand for CCR7, as well as CXCR3 and the virorecptor M3. \u003c\/p\u003e \u003cp\u003e Sterile Filtered White lyophilized powder. Purified and tested for use in cell culture. \u003c\/p\u003e \u003cp\u003e Source:\u003cem\u003e Escherichia coli\u003c\/em\u003e \u003c\/p\u003e \u003cp\u003e MW: ~12.1 kDa (110  amino acids) \u003c\/p\u003e \u003cp\u003e Purity: \u0026gt;97% by SDS-PAGE  and HPLC analyses \u003c\/p\u003e \u003cp\u003e Biological Activity: Fully biologically  active when compared to standard. The biological activity determined by a  chemotaxis bioassay using murine T-lymphocytes is in a concentration of 10-100  ng\/ml. \u003c\/p\u003e \u003cp\u003e Storage\/Handling: Store desiccated at  -20°C. \u003c\/p\u003e \u003cp\u003e MGI: \u003ca href=\"http:\/\/www.genenames.org\/cgi-bin\/gene_symbol_report?hgnc_id=HGNC:10620\"\u003e10620\u003c\/a\u003e \u003c\/p\u003e \u003cp\u003e NOT FOR HUMAN USE! \u003c\/p\u003e \u003cp\u003e \u003cstrong\u003eAdditional resources for this protein may be found at:\u003c\/strong\u003e \u003cbr\u003e \u003ca href=\"http:\/\/www.omim.org\/entry\/602737\"\u003eOMIM\u003c\/a\u003e \u003cbr\u003e \u003c\/p\u003e","brand":"GoldBio","offers":[{"title":"5 μg","offer_id":44854834102329,"sku":"2340-21-5","price":195.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0718\/5235\/9737\/files\/2340-21_20structure.jpg?v=1757447770"},{"product_id":"ccl19-murine","title":"CCL19, Murine","description":"\u003cp\u003e \u003cstrong\u003eGoldBio growth factors are manufactured for RESEARCH USE ONLY and cannot be sold for human consumption!\u003c\/strong\u003e \u003c\/p\u003e \u003cp\u003e Recombinant  Murine Chemokine (C-C motif) Ligand 19 (CCL19) \u003cbr\u003e Macrophage  Inflammatory Protein 3, Beta (MIP3B, MIP-3β) \u003cbr\u003e Small  Inducible Cytokine Subfamily A Member 17 (SCYA17) \u003cbr\u003e Exodus 3,  Exodus-3 \u003cbr\u003e EBI1  Ligand Chemokine (ELC) \u003cbr\u003e Chemokine  Beta 11 (CkB11, Ck-β-11) \u003c\/p\u003e \u003cp\u003e CCL19 is a chemokine containing four conserved cysteine residues, two of which are adjacent. It is expressed by dendritic cells in lymph nodes, as well as in spleen and thymus tissue. Expression of CCL19 is upregulated by IFNG and TNF-alpha. CCL19 has shown to be chemotactic for T-cells and B-cells, as well as CFU granulocyte macrophages. It plays a role in mobilization of dendritic cells from the epidermis to lymph nodes and development of local lymphoid tissues. CCL19 is a ligand for CCR7 (EBI1), as well as the atypical chemokine receptors CCRL1 and CCRL2. \u003c\/p\u003e \u003cp\u003e Sterile Filtered White lyophilized powder. Purified and tested for use in cell culture. \u003c\/p\u003e \u003cp\u003e Source: \u003cem\u003eEscherichia coli\u003c\/em\u003e \u003c\/p\u003e \u003cp\u003e MW: ~9.2 kDa (83 amino  acids) \u003c\/p\u003e \u003cp\u003e Purity: \u0026gt;97% by SDS-PAGE  and HPLC analyses \u003c\/p\u003e \u003cp\u003e Biological Activity: Fully biologically  active when compared to standard. The biological activity determined by a  chemotaxis bioassay using human mature dendritic cells is in a concentration  of 10-100 ng\/ml. \u003c\/p\u003e \u003cp\u003e Storage\/Handling: Store desiccated at  -20°C. \u003c\/p\u003e \u003cp\u003e MGD: \u003ca href=\"http:\/\/www.informatics.jax.org\/marker\/MGI:1346316\"\u003e1346316\u003c\/a\u003e \u003c\/p\u003e \u003cp\u003e NOT FOR HUMAN USE! \u003c\/p\u003e \u003cp\u003e \u003cstrong\u003eAdditional resources for this protein may be found at:\u003c\/strong\u003e \u003cbr\u003e \u003ca href=\"http:\/\/www.omim.org\/entry\/602227\"\u003eOMIM\u003c\/a\u003e \u003cbr\u003e \u003c\/p\u003e","brand":"GoldBio","offers":[{"title":"5 μg","offer_id":44854834167865,"sku":"2340-19-5","price":195.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0718\/5235\/9737\/files\/Default_No_Image_Bottle_png.png?v=1757612830"},{"product_id":"ccl20-murine","title":"CCL20, Murine","description":"\u003cp\u003e \u003cstrong\u003eGoldBio growth factors are manufactured for RESEARCH USE ONLY and cannot be sold for human consumption!\u003c\/strong\u003e \u003c\/p\u003e \u003cp\u003e Recombinant  Murine Chemokine (C-C motif) Ligand 20 (CCL20) \u003cbr\u003e Liver and Activation  Regulated Chemokine (LARC) \u003cbr\u003e Small  Inducible Cytokine Subfamily A Member 20 (SCYA20) \u003cbr\u003e Chemokine  Beta 4 (Ckb4, Ck-β-4) \u003cbr\u003e Exodus,  Exodus-1 \u003cbr\u003e Macrophage  Inflammatory Protein 3, Alpha (MIP3α, MIP-3α) \u003c\/p\u003e \u003cp\u003e CCL20 is a chemokine containing four conserved cysteine residues, two of which are adjacent. It is expressed in the liver as well as in lymphocytes, monocytes, and leukemia cells that have been induced by a mediator of inflammation, such as IFNG, IL1B, LPS, or PMA. It is upregulated in psoriasis because of proinflammatory mediators produced in the skin and attracts T lymphocytes to lesions. CCL20 is chemotactic mainly for lymphocytes, but also for granulocytes and immature dendritic cells and it plays a role in development of mucosal lymphoid tissue. It is a ligand for CCR6. \u003c\/p\u003e \u003cp\u003e Sterile Filtered White lyophilized powder. Purified and tested for use in cell culture. \u003c\/p\u003e \u003cp\u003e Source:\u003cem\u003e Escherichia coli\u003c\/em\u003e \u003c\/p\u003e \u003cp\u003e MW: ~8.0 kDa (70 amino  acids) \u003c\/p\u003e \u003cp\u003e Purity: \u0026gt;96% by SDS-PAGE  and HPLC analyses \u003c\/p\u003e \u003cp\u003e Biological Activity: Fully biologically active  when compared to standard. The biologically active determined by a chemotaxis  bioassay using human CCR6 transfected murine BaF3 cells is in a concentration  range of 0.1-10 ng\/ml. \u003c\/p\u003e \u003cp\u003e Storage\/Handling: Store desiccated at  -20°C. \u003c\/p\u003e \u003cp\u003e MGD: \u003ca href=\"http:\/\/www.informatics.jax.org\/marker\/MGI:1329031\"\u003e1329031\u003c\/a\u003e \u003c\/p\u003e \u003cp\u003e NOT FOR HUMAN USE! \u003c\/p\u003e \u003cp\u003e \u003cstrong\u003eAdditional resources for this protein may be found at:\u003c\/strong\u003e \u003cbr\u003e \u003ca href=\"http:\/\/www.omim.org\/entry\/601960\"\u003eOMIM\u003c\/a\u003e\u003ca href=\"http:\/\/www.copewithcytokines.de\/cope.cgi?key=LARC\"\u003e\u003c\/a\u003e \u003c\/p\u003e","brand":"GoldBio","offers":[{"title":"5 μg","offer_id":44854834200633,"sku":"2340-20-5","price":195.0,"currency_code":"USD","in_stock":true},{"title":"100 μg","offer_id":44854834233401,"sku":"2340-20-100","price":1254.0,"currency_code":"USD","in_stock":true},{"title":"500 μg","offer_id":44854834266169,"sku":"2340-20-500","price":2589.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0718\/5235\/9737\/files\/2340-20_20rMuCCL20.png?v=1757447773"},{"product_id":"ccl17-murine","title":"CCL17, Murine","description":"\u003cp\u003e \u003cstrong\u003eGoldBio growth factors are manufactured for RESEARCH USE ONLY and cannot be sold for human consumption!\u003c\/strong\u003e \u003c\/p\u003e \u003cp\u003e Recombinant  Murine Chemokine (C-C motif) Ligand 17 (CCL17) \u003cbr\u003e Thymus and  Activation Regulated Chemokine (TARC) \u003cbr\u003e Small  Inducible Cytokine Subfamily A Member 17 (SCYA17) \u003c\/p\u003e \u003cp\u003e CCL17 is a chemokine containing four conserved cysteine residues, two of which are adjacent. It is expressed constitutively in the thymus and lymph nodes and transiently in peripheral blood mononuclear cells that have been induced by phytogemagglutinin. It is chemotactic for T-cells and plays a role in T-cell development trafficking, and activation. CCL17 promotes atherosclerosis by restricting the maintenance of regulatory T-cells, thereby limiting their expansion. It is a ligand for CCR4, CCR8, and the erythrocyte receptor ACKR1. \u003c\/p\u003e \u003cp\u003e Sterile Filtered White lyophilized powder. Purified and tested for use in cell culture. \u003c\/p\u003e \u003cp\u003e Source: \u003cem\u003eEscherichia coli\u003c\/em\u003e \u003c\/p\u003e \u003cp\u003e MW: ~7.9 kDa (70 amino  acids) \u003c\/p\u003e \u003cp\u003e Purity: \u0026gt;97% by SDS-PAGE  and HPLC analyses \u003c\/p\u003e \u003cp\u003e Biological Activity: Fully biologically  active when compared to standard. The biological activity determined by a  chemotaxis bioassay using human T-lymphocytes is in a concentration of 1.0-10  ng\/ml. \u003c\/p\u003e \u003cp\u003e Storage\/Handling: Store desiccated at  -20°C. \u003c\/p\u003e \u003cp\u003e MGD: \u003ca href=\"http:\/\/www.informatics.jax.org\/marker\/MGI:1329039\"\u003e1329039\u003c\/a\u003e \u003c\/p\u003e \u003cp\u003e NOT FOR HUMAN USE! \u003c\/p\u003e \u003cp\u003e \u003cstrong\u003eAdditional resources for this protein may be found at:\u003c\/strong\u003e \u003cbr\u003e \u003ca href=\"http:\/\/www.omim.org\/entry\/601520\"\u003eOMIM\u003c\/a\u003e \u003cbr\u003e \u003c\/p\u003e","brand":"GoldBio","offers":[{"title":"5 μg","offer_id":44854834298937,"sku":"2340-17-5","price":195.0,"currency_code":"USD","in_stock":true},{"title":"100 μg","offer_id":44854834331705,"sku":"2340-17-100","price":1254.0,"currency_code":"USD","in_stock":true},{"title":"500 μg","offer_id":44854834364473,"sku":"2340-17-500","price":2589.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0718\/5235\/9737\/files\/2340-17_20rMuCCL17.png?v=1757447776"},{"product_id":"ccl12-murine","title":"CCL12, Murine","description":"\u003cp\u003e \u003cstrong\u003eGoldBio growth factors are manufactured for RESEARCH USE ONLY and cannot be sold for human consumption!\u003c\/strong\u003e \u003c\/p\u003e \u003cp\u003e Recombinant  Murine Chemokine (C-C motif) Ligand 12 (CCL12) \u003cbr\u003e Monocyte  Chemotactic Protein 5 (MCP5, MCP-5) \u003cbr\u003e Small  Inducible Cytokine Subfamily A Member 12 (SCYA12) \u003c\/p\u003e \u003cp\u003e Murine CCL12 is a chemokine containing four conserved cysteine residues, of which the first two are adjacent. It is expressed by macrophages and in lymph nodes and thymus tissue. Expression of CCL12 is upregulated after hypoxia and during bacterial infection and allergic inflammation. It is chemotactic for peripheral blood monocytes and fibrocytes and may play a critical role in the early stages of inflammation, as well as in joint and growth plate development. CCL12 is a ligand for CCR2. \u003c\/p\u003e \u003cp\u003e Sterile Filtered White lyophilized powder. Purified and tested for use in cell culture. \u003c\/p\u003e \u003cp\u003e Source: \u003cem\u003eEscherichia coli\u003c\/em\u003e \u003c\/p\u003e \u003cp\u003e MW: ~9.3 kDa (82 amino  acids) \u003c\/p\u003e \u003cp\u003e Purity: \u0026gt;95% by SDS-PAGE  and HPLC analyses \u003c\/p\u003e \u003cp\u003e Biological Activity: Fully biologically  active when compared to standard. The biological activity determined by a  chemotaxis bioassay using human peripheral blood monocytes is in a concentration  of 10-50 ng\/ml. \u003c\/p\u003e \u003cp\u003e Storage\/Handling: Store desiccated at  -20°C. \u003c\/p\u003e \u003cp\u003e MGD: \u003ca href=\"http:\/\/www.informatics.jax.org\/marker\/MGI:108224\"\u003e108224\u003c\/a\u003e \u003c\/p\u003e \u003cp\u003e NOT FOR HUMAN USE! \u003c\/p\u003e \u003cp\u003e \u003cstrong\u003e\u003cbr\u003e\u003c\/strong\u003e\u003ca href=\"http:\/\/www.copewithcytokines.de\/cope.cgi?key=MCP-5\"\u003e\u003c\/a\u003e \u003c\/p\u003e","brand":"GoldBio","offers":[{"title":"5 μg","offer_id":44854834397241,"sku":"2340-12-5","price":195.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0718\/5235\/9737\/files\/2340-12_20structure.jpg?v=1757447775"},{"product_id":"ccl9-ccl10-murine","title":"CCL9 (CCL10), Murine","description":"\u003cp\u003e \u003cstrong\u003eGoldBio growth factors are manufactured for RESEARCH USE ONLY and cannot be sold for human consumption!\u003c\/strong\u003e \u003c\/p\u003e \u003cp\u003e Recombinant  Murine Chemokine (C-C motif) Ligand 9 (CCL9) \u003cbr\u003e Recombinant  Murine Chemokine (C-C motif) Ligand 10 (CCL10) \u003cbr\u003e Small  Inducible Cytokine Subfamily A Member 9 (SCYA9) \u003cbr\u003e Small Inducible Cytokine Subfamily A Member 10  (SCYA10) \u003cbr\u003e Macrophage  Inflammatory Protein 1, Gamma (MIP1γ, MIP-1γ) \u003cbr\u003e MIP-related  protein 2 (MRP2, MRP-2) \u003cbr\u003e CCF18 \u003c\/p\u003e \u003cp\u003e CCL9 is a chemokine containing six conserved cysteine residues that form three disulfide bonds essential for biological activity. It circulates in the blood of healthy animals and is expressed constitutively in macrophages and myeloid cell lines. CCL9 displays chemotaxis for neutrophils, CD4+ T lymphocytes, and Peyer’s patch dendritic cells. Upon injection of CCL9, fever and inflammation are induced. CCL9 plays a major role in osteoclastogenesis and inhibits colony formation of bone marrow myeloid immature progenitors. It is a ligand for CCR1 and CCR3. Murine CCL9 has also been identified as murine CCL10 and is most homologous to Human CCL15. \u003c\/p\u003e \u003cp\u003e Sterile Filtered White lyophilized powder. Purified and tested for use in cell culture. \u003c\/p\u003e \u003cp\u003e Source: \u003cem\u003eEscherichia coli\u003c\/em\u003e \u003c\/p\u003e \u003cp\u003e MW: ~11.6 kDa (101  amino acids) \u003c\/p\u003e \u003cp\u003e Purity: \u0026gt;95% by SDS-PAGE  and HPLC analyses \u003c\/p\u003e \u003cp\u003e Biological Activity: Fully biologically  active when compared to standard. The biological activity determined by a  chemotaxis bioassay using human neutrophils is in a concentration of 0.1-10  ng\/ml. \u003c\/p\u003e \u003cp\u003e Storage\/Handling: Store desiccated at  -20°C. \u003c\/p\u003e \u003cp\u003e MGD: \u003ca href=\"http:\/\/www.informatics.jax.org\/marker\/MGI:104533\"\u003e104533\u003c\/a\u003e \u003c\/p\u003e \u003cp\u003e NOT FOR HUMAN USE! \u003c\/p\u003e \u003cp\u003e \u003cstrong\u003eAdditional resources for this protein may be found at:\u003c\/strong\u003e \u003cbr\u003e\u003ca href=\"http:\/\/www.uniprot.org\/uniprot\/P51670\"\u003eUniProt\u003c\/a\u003e \u003c\/p\u003e","brand":"GoldBio","offers":[{"title":"5 μg","offer_id":44854834430009,"sku":"2340-09-5","price":195.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0718\/5235\/9737\/files\/Default_No_Image_Bottle_png.png?v=1757612830"},{"product_id":"ccl11-murine","title":"CCL11, Murine","description":"\u003cp\u003e \u003cstrong\u003eGoldBio growth factors are manufactured for RESEARCH USE ONLY and cannot be sold for human consumption!\u003c\/strong\u003e \u003c\/p\u003e \u003cp\u003e Recombinant  Murine Chemokine (C-C motif) Ligand 11 (CCL11) \u003cbr\u003e Eotaxin,  Eotaxin 1 \u003cbr\u003e Small  Inducible Cytokine Subfamily A Member 11 (SCYA11) \u003c\/p\u003e \u003cp\u003e Murine CCL11 is a chemokine containing four conserved cysteine residues, of which the first two are adjacent. It is expressed in fibroblasts, epithelial cells, smooth muscle cells, and dendritic cells. Expression of CCL11 is upregulated by several proinflammatory cytokines, including IL1A and TNFA, and is inhibited by IFNG. It is strongly and selectively chemotactic for eosinophils and induces a calcium flux response in eosinophils. CCL11 is involved in a variety of eosinophilic inflammatory diseases. CCL11 is a ligand primarily for CCR3, but also CCR1, CCR2, CCR5, and ACKR2 (D6). \u003c\/p\u003e \u003cp\u003e Sterile Filtered White lyophilized powder. Purified and tested for use in cell culture. \u003c\/p\u003e \u003cp\u003e Source: \u003cem\u003eEscherichia coli\u003c\/em\u003e \u003c\/p\u003e \u003cp\u003e MW: ~8.4 kDa (74 amino  acids) \u003c\/p\u003e \u003cp\u003e Purity: \u0026gt;96% by SDS-PAGE  and HPLC analyses \u003c\/p\u003e \u003cp\u003e Biological Activity: Fully biologically  active when compared to standard. The biological activity determined by a  chemotaxis bioassay using purified eosinophils is in a concentration of 100-1000  ng\/ml. \u003c\/p\u003e \u003cp\u003e Storage\/Handling: Store desiccated at  -20°C. \u003c\/p\u003e \u003cp\u003e MGD: \u003ca href=\"http:\/\/www.informatics.jax.org\/marker\/MGI:103576\"\u003e103576\u003c\/a\u003e \u003c\/p\u003e \u003cp\u003e NOT FOR HUMAN USE! \u003c\/p\u003e \u003cp\u003e \u003cstrong\u003eAdditional resources for this protein may be found at:\u003c\/strong\u003e \u003cbr\u003e \u003ca href=\"http:\/\/www.omim.org\/entry\/601156\"\u003eOMIM\u003c\/a\u003e \u003cbr\u003e \u003c\/p\u003e","brand":"GoldBio","offers":[{"title":"5 μg","offer_id":44854834462777,"sku":"2340-11-5","price":195.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0718\/5235\/9737\/files\/2340-11_20structure.jpg?v=1757447779"},{"product_id":"ccl8-murine","title":"CCL8, Murine","description":"\u003cp\u003e \u003cstrong\u003eGoldBio growth factors are manufactured for RESEARCH USE ONLY and cannot be sold for human consumption!\u003c\/strong\u003e \u003c\/p\u003e \u003cp\u003e Recombinant  Human Chemokine (C-C motif) Ligand 8 (CCL8) \u003cbr\u003e Monocyte  Chemoattractant Protein 2 (MCP2, MCP-2) \u003cbr\u003e Small  Inducible Cytokine Subfamily A Member 8 (SCYA8) \u003cbr\u003e HC14 \u003c\/p\u003e \u003cp\u003e Murine CCL8 is a chemokine containing four conserved cysteine residues, the first two of which are adjacent. It is expressed by peripheral blood leukocytes, as well as a variety of other cells. Expression of CCL8 is induced by IFNG, IFNB, IL1B, and various cytokine inducers such as viruses, endotoxins, and mitogens. It is chemotactic for monocytes, lymphocytes, basophils, and eosinophils and plays a role in tumor-associated leukocyte infiltration by recruiting leukocytes to sites of inflammation. CCL8 also inhibits CCR5-mediated HIV-1 entry and replication. CCL8 is a ligand for CCR1, CCR2B, CCR3, CCR5, CCR8, ACKR2, and ACKR4. \u003c\/p\u003e \u003cp\u003e Sterile Filtered White lyophilized powder. Purified and tested for use in cell culture. \u003c\/p\u003e \u003cp\u003e Source:\u003cem\u003e Escherichia coli\u003c\/em\u003e \u003c\/p\u003e \u003cp\u003e MW: ~8.5 kDa (74 amino  acids) \u003c\/p\u003e \u003cp\u003e Purity: \u0026gt;97% by SDS-PAGE  and HPLC analyses \u003c\/p\u003e \u003cp\u003e Biological Activity: Fully biologically  active when compared to standard. The biological activity determined by a  chemotaxis bioassay using human peripheral blood monocytes is in a concentration  of 10-100 ng\/ml. \u003c\/p\u003e \u003cp\u003e Storage\/Handling: Store desiccated at  -20°C. \u003c\/p\u003e \u003cp\u003e MGD: \u003ca href=\"http:\/\/www.informatics.jax.org\/marker\/MGI:101878\"\u003e101878\u003c\/a\u003e \u003c\/p\u003e \u003cp\u003e NOT FOR HUMAN USE! \u003c\/p\u003e \u003cp\u003e \u003cstrong\u003eAdditional resources for this protein may be found at:\u003c\/strong\u003e \u003cbr\u003e \u003ca href=\"http:\/\/www.omim.org\/entry\/602283\"\u003eOMIM\u003c\/a\u003e \u003cbr\u003e \u003c\/p\u003e","brand":"GoldBio","offers":[{"title":"5 μg","offer_id":44854834495545,"sku":"2340-08-5","price":195.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0718\/5235\/9737\/files\/Default_No_Image_Bottle_png.png?v=1757612830"},{"product_id":"ccl7-murine","title":"CCL7, Murine","description":"\u003cp\u003e \u003cstrong\u003eGoldBio growth factors are manufactured for RESEARCH USE ONLY and cannot be sold for human consumption!\u003c\/strong\u003e \u003c\/p\u003e \u003cp\u003e Recombinant  Murine Chemokine (C-C motif) Ligand 7 (CCL7) \u003cbr\u003e Monocyte  Chemoattractant Protein 3 (MCP3, MCP-3) \u003cbr\u003e Small  Inducible Cytokine Subfamily A Member 7 (SCYA7) \u003cbr\u003e Fibroblast-Inducible  Cytokine (FIC) \u003cbr\u003e Mast Cell  Activation-Related Chemokine (MARC) \u003c\/p\u003e \u003cp\u003e Murine CCL7 is a chemokine containing four conserved cysteine residues, of which the first two are adjacent. It was first isolated from murine mast cells stimulated by IgE interacting with an antigen and is expressed and secreted by T cells, monocytes, macrophages, and a variety of tumor cell lines. Expression is induced by IFNG and inhibited by IL13. CCL7 is chemotactic for monocytes, macrophages, eosinophils, and NK cells and regulates protease secretion by macrophages which may contribute to metastasis of cancer cells. CCL7 is a ligand primarily for CCR2, but also for CCR1, CCR3, CCR10, and ACKR2 (D6). \u003c\/p\u003e \u003cp\u003e Sterile Filtered White lyophilized powder. Purified and tested for use in cell culture. \u003c\/p\u003e \u003cp\u003e Source: \u003cem\u003eEscherichia coli\u003c\/em\u003e \u003c\/p\u003e \u003cp\u003e MW: ~8.5 kDa (74 amino  acids) \u003c\/p\u003e \u003cp\u003e Purity: \u0026gt;95% by SDS-PAGE  and HPLC analyses \u003c\/p\u003e \u003cp\u003e Biological Activity: Fully biologically  active when compared to standard. The biological activity determined by a  chemotaxis bioassay using human monocytes is in a concentration of 100-300  ng\/ml. \u003c\/p\u003e \u003cp\u003e Storage\/Handling: Store desiccated at  -20°C. \u003c\/p\u003e \u003cp\u003e MGD: \u003ca href=\"http:\/\/www.informatics.jax.org\/marker\/MGI:99512\"\u003e99512\u003c\/a\u003e \u003c\/p\u003e \u003cp\u003e NOT FOR HUMAN USE! \u003c\/p\u003e \u003cp\u003e \u003cstrong\u003eAdditional resources for this protein may be found at:\u003c\/strong\u003e \u003cbr\u003e \u003ca href=\"http:\/\/www.omim.org\/entry\/158106\"\u003eOMIM\u003c\/a\u003e \u003cbr\u003e \u003c\/p\u003e","brand":"GoldBio","offers":[{"title":"10 μg","offer_id":44854834528313,"sku":"2340-07-10","price":278.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0718\/5235\/9737\/files\/2340-07_20structure.jpg?v=1757447782"},{"product_id":"ccl6-murine","title":"CCL6, Murine","description":"\u003cp\u003e \u003cstrong\u003eGoldBio growth factors are manufactured for RESEARCH USE ONLY and cannot be sold for human consumption!\u003c\/strong\u003e \u003c\/p\u003e \u003cp\u003e Recombinant  Murine Chemokine (C-C motif) Ligand 6 (CCL6) \u003cbr\u003e Small  Inducible Cytokine Subfamily A Member 6 (SCYA6) \u003cbr\u003e Macrophage  Inflammatory Protein-Related Protein 1 (MRP1, MRP-1) \u003cbr\u003e C10 \u003c\/p\u003e \u003cp\u003e Murine CCL6 is a chemokine containing four conserved cysteine residues, two of which are adjacent. It is expressed primarily in microglia and other macrophages, as well as myelopoietic bone marrow cells. Upregulation of expression of CCL6 has been observed after stimulation with IFNG, CSF1, CSF2, IL3, and IL4. CCL6 expression is also stimulated by IL-13 and is required for IL-13 stimulation of other chemokines. CCL6 is chemotactic for macrophages and lymphocytes and acts as a ligand primarily for CCR1. CCL6 has only been observed in rodents thus far; murine CCL6 is most homologous to human CCL23. \u003c\/p\u003e \u003cp\u003e Sterile Filtered White lyophilized powder. Purified and tested for use in cell culture. \u003c\/p\u003e \u003cp\u003e Source:\u003cem\u003e Escherichia coli\u003c\/em\u003e \u003c\/p\u003e \u003cp\u003e MW: ~10.7 kDa (95  amino acids) \u003c\/p\u003e \u003cp\u003e Purity: \u0026gt;97% by SDS-PAGE  and HPLC analyses \u003c\/p\u003e \u003cp\u003e Biological Activity: Fully biologically  active when compared to standard. The biologically active determined by a  chemotaxis bioassay using human CCR1 transfected murine BaF3 cells is in a  concentration range of 10-100 ng\/ml. \u003c\/p\u003e \u003cp\u003e Storage\/Handling: Store desiccated at  -20°C. \u003c\/p\u003e \u003cp\u003e MGD: \u003ca href=\"http:\/\/www.informatics.jax.org\/marker\/MGI:98263\"\u003e98263\u003c\/a\u003e \u003c\/p\u003e \u003cp\u003e NOT FOR HUMAN USE! \u003cbr\u003e \u003cbr\u003e\u003ca href=\"http:\/\/www.copewithcytokines.de\/cope.cgi?key=C10\"\u003e\u003c\/a\u003e \u003c\/p\u003e","brand":"GoldBio","offers":[{"title":"10 μg","offer_id":44854834561081,"sku":"2340-06-10","price":278.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0718\/5235\/9737\/files\/Default_No_Image_Bottle_png.png?v=1757612830"},{"product_id":"ccl5-murine","title":"CCL5, Murine","description":"\u003cp\u003e \u003cstrong\u003eGoldBio growth factors are manufactured for RESEARCH USE ONLY and cannot be sold for human consumption!\u003c\/strong\u003e \u003c\/p\u003e \u003cp\u003e Recombinant  Murine Chemokine (C-C motif) Ligand 5 (CCL5) \u003cbr\u003e Regulated  Upon Activation, Normally T-Expressed, and Presumably Secreted (RANTES) \u003cbr\u003e Small  Inducible Cytokine Subfamily A Member 5 (SCYA5) \u003cbr\u003e T-Cell  Specific Protein p228 (TCP228) \u003cbr\u003e Eosinophil  Chemotactic Polypeptide 1 (EoCP1) \u003c\/p\u003e \u003cp\u003e Murine CCL5 is a chemokine containing four conserved cysteine residues, the first two of which are adjacent. It is expressed and secreted by T lymphocytes. Expression of CCL5 is induced by TNF-alpha and IL1-alpha and inhibited by stimulation of T lymphocytes. CCL5 is chemotactic for T lymphocytes, eosinophils, basophils, and monocytes and plays a role in recruiting these cells to inflammatory sites. It also induces proliferation and activation of CHAK cells and is an HSV and HIV-suppressive factor. CCL5 is a ligand for CCR1, CCR3, CCR5, and the viroreceptor M3. Murine CCL5 is chemotactic for both murine and human leukocytes in a dose-dependent fashion. \u003c\/p\u003e \u003cp\u003e Sterile Filtered White lyophilized powder. Purified and tested for use in cell culture. \u003c\/p\u003e \u003cp\u003e Source: \u003cem\u003eEscherichia coli\u003c\/em\u003e \u003c\/p\u003e \u003cp\u003e MW: ~7.9 kDa (68 amino  acids) \u003c\/p\u003e \u003cp\u003e Purity: \u0026gt;97% by SDS-PAGE  and HPLC analyses \u003c\/p\u003e \u003cp\u003e Biological Activity: Fully biologically  active when compared to standard. The biological activity determined by a  chemotaxis bioassay using human T-lymphocytes is in a concentration of 1-10  ng\/ml. \u003c\/p\u003e \u003cp\u003e Storage\/Handling: Store desiccated at  -20°C. \u003c\/p\u003e \u003cp\u003e MGD: \u003ca href=\"http:\/\/www.informatics.jax.org\/marker\/MGI:98262\"\u003e98262\u003c\/a\u003e \u003c\/p\u003e \u003cp\u003e NOT FOR HUMAN USE! \u003c\/p\u003e \u003cp\u003e \u003cstrong\u003eAdditional resources for this protein may be found at:\u003c\/strong\u003e \u003cbr\u003e \u003ca href=\"http:\/\/www.omim.org\/entry\/187011\"\u003eOMIM\u003c\/a\u003e \u003cbr\u003e \u003c\/p\u003e","brand":"GoldBio","offers":[{"title":"5 μg","offer_id":44854834593849,"sku":"2340-05-5","price":195.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0718\/5235\/9737\/files\/2340-05_20structure.jpg?v=1757447783"},{"product_id":"ccl4-murine","title":"CCL4, Murine","description":"\u003cp\u003e \u003cstrong\u003eGoldBio growth factors are manufactured for RESEARCH USE ONLY and cannot be sold for human consumption!\u003c\/strong\u003e \u003c\/p\u003e \u003cp\u003e Recombinant  Murine Chemokine (C-C motif) Ligand 4 (CCL4) \u003cbr\u003e Macrophage  Inflammatory Protein 1, Beta (MIP1B, MIP1B1) \u003cbr\u003e Small  Inducible Cytokine Subfamily A Member 4 (SCYA4) \u003cbr\u003e Immune  Activation 2 (ACT2, ACT-2) \u003c\/p\u003e \u003cp\u003e Murine CCl4 is a chemokine containing four conserved cysteine residues, of which the first two are adjacent. It is expressed and secreted by T-cells, B-cells, monocytes, and various tumor cells lines. Expression of CCL4 is induced by IL2 and mitogens, such as phytohemmagglutinin, lipopolysaccharide, and the peptidoglycan wall of \u003cem\u003eS. aureus\u003c\/em\u003e and expression is inhibited by glucocorticoids, TGF-beta, and cyclosporin A. CCL4 is an HIV-suppressive factor produced by CD8+ T-cells. It also binds to HSV-1 virions and generates pores in the envelope of HSV-1. CCL4 is a ligand for CCR1, CCR3, CCR5, CCR8, and ACKR2 (D6). Murine CCL4 is active on both human and murine hematopoietic cells. \u003c\/p\u003e \u003cp\u003e Sterile Filtered White lyophilized powder. Purified and tested for use in cell culture. \u003c\/p\u003e \u003cp\u003e Source:\u003cem\u003e Escherichia coli\u003c\/em\u003e \u003c\/p\u003e \u003cp\u003e MW: ~7.8 kDa (69 amino  acids) \u003c\/p\u003e \u003cp\u003e Purity: \u0026gt;97% by SDS-PAGE  and HPLC analyses \u003c\/p\u003e \u003cp\u003e Biological Activity: Fully biologically  active when compared to standard. The biological activity determined by a  chemotaxis bioassay using human monocytes is in a concentration of 20-100  ng\/ml. \u003c\/p\u003e \u003cp\u003e Storage\/Handling: Store desiccated at  -20°C. \u003c\/p\u003e \u003cp\u003e MGD: \u003ca href=\"http:\/\/www.informatics.jax.org\/marker\/MGI:98261\"\u003e98261\u003c\/a\u003e \u003c\/p\u003e \u003cp\u003e NOT FOR HUMAN USE! \u003c\/p\u003e \u003cp\u003e \u003cstrong\u003eAdditional resources for this protein may be found at:\u003c\/strong\u003e \u003cbr\u003e \u003ca href=\"http:\/\/www.omim.org\/entry\/182284\"\u003eOMIM\u003c\/a\u003e \u003cbr\u003e \u003c\/p\u003e","brand":"GoldBio","offers":[{"title":"10 μg","offer_id":44854834626617,"sku":"2340-04-10","price":278.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0718\/5235\/9737\/files\/2340-04_20structure.jpg?v=1757447785"},{"product_id":"ccl3-murine","title":"CCL3, Murine","description":"\u003cp\u003e \u003cstrong\u003eGoldBio growth factors are manufactured for RESEARCH USE ONLY and cannot be sold for human consumption!\u003c\/strong\u003e \u003c\/p\u003e \u003cp\u003e Recombinant  Murine Chemokine (C-C motif) Ligand 3 (CCL3) \u003cbr\u003e Monocyte  Chemoattractant Protein 1, Alpha (MCP1α, MCP-1α) \u003cbr\u003e Small  Inducible Cytokine Subfamily A Member 3 (SCYA3) \u003cbr\u003e LD78-Alpha \u003cbr\u003e Macrophage  Inflammatory Protein 1, Alpha (MIP1A) \u003cbr\u003e G0\/G1  Switch Gene 19-1 (GOS-19-1) \u003c\/p\u003e \u003cp\u003e Murine CCL3 is a chemokine containing four conserved cysteine residues, of which the first two are adjacent. It is expressed by T-cells, B-cells, and various tumor cells lines and has been identified as a G0\/G1 switch gene in these cells. CCL3 plays an important role in the recruitment and activation of polymorphonuclear leukocytes in the acute inflammatory state, an inhibitory role in hematopoiesis, and displays inhibitory activity against strains of HIV-1, HIV-2, and SIV. CCL3 is a ligand for CCR1, CCR4, and the HIV-1 coreceptor CCR5. Activation of CCR5 through CCL3 activates a G-protein pathway through GNAI2 and a tyrosine phosphorylation through JAK2. \u003c\/p\u003e \u003cp\u003e Sterile Filtered White lyophilized powder. Purified and tested for use in cell culture. \u003c\/p\u003e \u003cp\u003e Source: \u003cem\u003eEscherichia coli\u003c\/em\u003e \u003c\/p\u003e \u003cp\u003e MW: ~7.9 kDa (69 amino  acids) \u003c\/p\u003e \u003cp\u003e Purity: \u0026gt;98% by SDS-PAGE  and HPLC analyses \u003c\/p\u003e \u003cp\u003e Biological Activity: Fully biologically  active when compared to standard. The biological activity determined by a  chemoattract bioassay using murine splenocytes is in a concentration range of  10-100 ng\/ml. \u003c\/p\u003e \u003cp\u003e Storage\/Handling: Store desiccated at  -20°C. \u003c\/p\u003e \u003cp\u003e MGD: \u003ca href=\"http:\/\/www.informatics.jax.org\/marker\/MGI:98260\"\u003e98260\u003c\/a\u003e \u003c\/p\u003e \u003cp\u003e NOT FOR HUMAN USE! \u003c\/p\u003e \u003cp\u003e \u003cstrong\u003eAdditional resources for this protein may be found at:\u003c\/strong\u003e \u003cbr\u003e \u003ca href=\"http:\/\/www.omim.org\/entry\/182283\"\u003eOMIM\u003c\/a\u003e \u003cbr\u003e \u003c\/p\u003e","brand":"GoldBio","offers":[{"title":"10 μg","offer_id":44854834659385,"sku":"2340-03-10","price":278.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0718\/5235\/9737\/files\/2340-03_20structure.jpg?v=1757447785"},{"product_id":"cx3cl1-murine","title":"CX3CL1, Murine","description":"\u003cp\u003e \u003cstrong\u003eGoldBio growth factors are manufactured for RESEARCH USE ONLY and cannot be sold for human consumption!\u003c\/strong\u003e \u003c\/p\u003e \u003cp\u003e Recombinant  Murine Chemokine (C-X3-C motif) Ligand 1 (CX3CL1) \u003cbr\u003e Fractalkine \u003cbr\u003e Small  Inducible Cytokine Subfamily D Member 1 (SCYD1) \u003cbr\u003e ATP-Binding  Cassette, Subfamily D Member 3 (ABCD-3) \u003cbr\u003e Neurotactin  (NTN) \u003c\/p\u003e \u003cp\u003e Murine CX3CL1 is a chemokine that is unlike most chemokines because it contains the C-X-X-X-C motif. It is expressed by neurons, endothelial cells, follicular dendritic cells, and some lymphocytes. Expression of CX3CL1 is induced by activation of the transcription factor NFKB1 through IFNG, IL1B, TNF, or LPS. CX3CL1 is chemotactic for T-cells and monocytes and plays a role in angiogenesis, as well as regulation of leukocyte traffic at the endothelium. It also functions as a survival factor for microglial cells. Knock-out mice lacking the \u003cem\u003eCX3CL1\u003c\/em\u003e gene appear nearly indistinguishable from wild-type mice, except for a decrease in leukocytes expressing surface marker F4\/80. CX3CL1 is a ligand for CX3CR1 as well as virus-encoded receptors M3 and US28. \u003c\/p\u003e \u003cp\u003e Sterile Filtered White lyophilized powder. Purified and tested for use in cell culture. \u003c\/p\u003e \u003cp\u003e Source: \u003cem\u003eEscherichia coli\u003c\/em\u003e \u003c\/p\u003e \u003cp\u003e MW: ~8.7 kDa (76 amino  acids) \u003c\/p\u003e \u003cp\u003e Purity: \u0026gt;97% by SDS-PAGE  and HPLC analyses \u003c\/p\u003e \u003cp\u003e Biological Activity: Fully biologically  active when compared to standard. The ED\u003csub\u003e50\u003c\/sub\u003e as determined by a cell proliferation assay  using human peripheral blood lymphocytes (PBL) is less than 0.5 μg\/ml,  corresponding to a specific activity of \u0026gt;2000 IU\/mg. \u003c\/p\u003e \u003cp\u003e Storage\/Handling: Store desiccated at  -20°C. \u003c\/p\u003e \u003cp\u003e MGD: \u003ca href=\"http:\/\/www.informatics.jax.org\/marker\/MGI:1097153\"\u003e1097153\u003c\/a\u003e \u003c\/p\u003e \u003cp\u003e NOT FOR HUMAN USE! \u003c\/p\u003e \u003cp\u003e \u003cstrong\u003eAdditional resources for this protein may be found at:\u003c\/strong\u003e \u003cbr\u003e \u003ca href=\"http:\/\/www.omim.org\/entry\/601880\"\u003eOMIM\u003c\/a\u003e \u003cbr\u003e \u003c\/p\u003e","brand":"GoldBio","offers":[{"title":"5 μg","offer_id":44854834724921,"sku":"2330-01-5","price":195.0,"currency_code":"USD","in_stock":true},{"title":"100 μg","offer_id":44854834757689,"sku":"2330-01-100","price":1254.0,"currency_code":"USD","in_stock":true},{"title":"500 μg","offer_id":44854834790457,"sku":"2330-01-500","price":2589.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0718\/5235\/9737\/files\/2330-01_20structure.jpg?v=1757447789"},{"product_id":"cxcl16-murine","title":"CXCL16, Murine","description":"\u003cp\u003e \u003cstrong\u003eGoldBio growth factors are manufactured for RESEARCH USE ONLY and cannot be sold for human consumption!\u003c\/strong\u003e \u003c\/p\u003e \u003cp\u003e Recombinant  Murine Chemokine (C-X-C motif) Ligand 16 (CXCL16) \u003cbr\u003e Scavenger  Receptor For Phosphatidylserine And Oxidized Low Density Lipoprotein (SR-PSOX,  SRPSOX) \u003cbr\u003e Small  Inducible Cytokine Subfamily B Member 16 (SCYB16) \u003c\/p\u003e \u003cp\u003e Murine CXCL16 is a CXC chemokine lacking the ELR motif. It is expressed by macrophages, monocytes, B-cells, and Schwann cells. Expression is induced by IFNG and TNF-α. CXCL16 is an integral membrane protein that is cleaved by ADAM10 to release the soluble active polypeptide into the extracellular space. The soluble protein is chemotactic for activated CD8 T-cells, induces calcium flux and regulates migration of T-cells. CXCL16 is a ligand for CXCR6, but also serves as a receptor for oxidized LDL and phosphadtidylserine. \u003c\/p\u003e \u003cp\u003e Sterile Filtered White lyophilized powder. Purified and tested for use in cell culture. \u003c\/p\u003e \u003cp\u003e Source: \u003cem\u003eEscherichia coli\u003c\/em\u003e \u003c\/p\u003e \u003cp\u003e MW: ~9.9 kDa (88 amino  acids) \u003c\/p\u003e \u003cp\u003e Purity: \u0026gt;98% by SDS-PAGE  and HPLC analyses \u003c\/p\u003e \u003cp\u003e Biological Activity: Fully biologically  active when compared to standard. The biological activity determined by a chemotaxis  bioassay using murine lymphocytes is in a concentration range of 20-1000  ng\/ml. \u003c\/p\u003e \u003cp\u003e Storage\/Handling: Store desiccated at  -20°C. \u003c\/p\u003e \u003cp\u003e MGD: \u003ca href=\"http:\/\/www.informatics.jax.org\/marker\/MGI:1932682\"\u003e1932682\u003c\/a\u003e \u003c\/p\u003e \u003cp\u003e NOT FOR HUMAN USE! \u003c\/p\u003e \u003cp\u003e \u003cstrong\u003eAdditional resources for this protein may be found at:\u003c\/strong\u003e \u003cbr\u003e \u003ca href=\"http:\/\/www.omim.org\/entry\/605398\"\u003eOMIM\u003c\/a\u003e \u003cbr\u003e \u003c\/p\u003e","brand":"GoldBio","offers":[{"title":"5 μg","offer_id":44854834823225,"sku":"2310-16-5","price":195.0,"currency_code":"USD","in_stock":true},{"title":"100 μg","offer_id":44854834855993,"sku":"2310-16-100","price":1254.0,"currency_code":"USD","in_stock":true},{"title":"500 μg","offer_id":44854834888761,"sku":"2310-16-500","price":2589.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0718\/5235\/9737\/files\/Default_No_Image_Bottle_png.png?v=1757612830"},{"product_id":"cxcl14-murine","title":"CXCL14, Murine","description":"\u003cp\u003e \u003cstrong\u003eGoldBio growth factors are manufactured for RESEARCH USE ONLY and cannot be sold for human consumption!\u003c\/strong\u003e \u003c\/p\u003e \u003cp\u003e Recombinant  Murine Chemokine (C-X-C motif) Ligand 14 (CXCL14) \u003cbr\u003e Macrophage  Inflammatory Protein 2, Gamma (MIP2γ, MIP-2-γ) \u003cbr\u003e Small  Inducible Cytokine Subfamily B Member 13 (SCYB13) \u003cbr\u003e B-Cell And  Monocyte-Activating Chemokine (BMAC) \u003cbr\u003e Homolog of  Human Breast and Kidney Cell Chemokine (BRAK) \u003cbr\u003e KS1 \u003c\/p\u003e \u003cp\u003e Murine CXCL14 is a CXC chemokine lacking the ELR motif. It is expressed constitutively in many normal tissues, including brain, lung, ovaries, kidneys, and muscle. CXCL14 is chemotactic for monocytes, macrophages, dendritic cells, activated NK cells, and B cells. It possesses tumor suppressing function in certain cancers possibly due to migrations of NK cells, inhibition of angiogenesis, and a reduction of settlement rate of tumor cells. However in contradiction, CXCL14 can induce tumor growth in other types of cancers. The effect on tumorigenesis may be changed through epigenetic silencing. CXCL14 is a natural antagonist for CXCR4 and inhibits CXCL12. \u003c\/p\u003e \u003cp\u003e Sterile Filtered White lyophilized powder. Purified and tested for use in cell culture. \u003c\/p\u003e \u003cp\u003e Source: \u003cem\u003eEscherichia coli\u003c\/em\u003e \u003c\/p\u003e \u003cp\u003e MW: ~9.4 kDa (77 amino  acids) \u003c\/p\u003e \u003cp\u003e Purity: \u0026gt;95% by SDS-PAGE  and HPLC analyses \u003c\/p\u003e \u003cp\u003e Biological Activity: Fully biologically  active when compared to standard. The biological activity determined by a chemotaxis  bioassay using human monocytes is in a concentration range of 1-10 ng\/ml. \u003c\/p\u003e \u003cp\u003e Storage\/Handling: Store desiccated at  -20°C. \u003c\/p\u003e \u003cp\u003e MGD: \u003ca href=\"http:\/\/www.informatics.jax.org\/marker\/MGI:1888514\"\u003e1888514\u003c\/a\u003e \u003c\/p\u003e \u003cp\u003e NOT FOR HUMAN USE! \u003c\/p\u003e \u003cp\u003e \u003cstrong\u003eAdditional resources for this protein may be found at:\u003c\/strong\u003e \u003cbr\u003e \u003ca href=\"http:\/\/www.omim.org\/entry\/604186\"\u003eOMIM\u003c\/a\u003e \u003cbr\u003e \u003c\/p\u003e","brand":"GoldBio","offers":[{"title":"5 μg","offer_id":44854834921529,"sku":"2310-14-5","price":195.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0718\/5235\/9737\/files\/2310-14_20structure.jpg?v=1757447791"},{"product_id":"cxcl12-beta-murine","title":"CXCL12-beta, Murine","description":"\u003cp\u003e \u003cstrong\u003eGoldBio growth factors are manufactured for RESEARCH USE ONLY and cannot be sold for human consumption!\u003c\/strong\u003e \u003c\/p\u003e \u003cp\u003e Recombinant  Murine Chemokine (C-X-C motif) Ligand 12, Beta (CXCL12β) \u003cbr\u003e Stromal  Cell-Derived Factor 1 (SDF1) \u003cbr\u003e Small  Inducible Cytokine Subfamily B Member 12 (SCYB12) \u003cbr\u003e Pre-B Cell  Growth-Stimulating Factor (PBSF) \u003cbr\u003e Thymic Lymphoma  Cell-Stimulating Factor (TLSF) \u003c\/p\u003e \u003cp\u003e CXCL12 is a CXC chemokine lacking the ELR motif. It was first found in bone marrow stromal cells and is expressed in bone marrow stromal cells constitutively as well as a wide variety of cells with the exception of blood cells. CXCL12 acts as a ligand for CXCR4. It is chemotactic for hematopoietic progenitor cells expressing CD34, mononuclear cells, and cerebellar granule cells. CXCL12 plays a role in lymphopoiesis, myelopoiesis, vascularization of the gastrointestinal tract, and cerebellar development. CXCL12-beta is one of six alternatively spliced isoforms of the CXCL12 gene and is used as the canonical sequence. \u003c\/p\u003e \u003cp\u003e Sterile Filtered White lyophilized powder. Purified and tested for use in cell culture. \u003c\/p\u003e \u003cp\u003e Source:\u003cem\u003e Escherichia coli\u003c\/em\u003e \u003c\/p\u003e \u003cp\u003e MW: ~8.5 kDa (72 amino  acids) \u003c\/p\u003e \u003cp\u003e Purity: \u0026gt;97% by SDS-PAGE  and HPLC analyses \u003c\/p\u003e \u003cp\u003e Biological Activity: Fully biologically  active when compared to standard. The biological activity determined by a  chemotaxis bioassay using human peripheral blood monocytes is in a concentration  range of 50-100 ng\/ml. \u003c\/p\u003e \u003cp\u003e Storage\/Handling: Store desiccated at  -20°C. \u003c\/p\u003e \u003cp\u003e MGD: \u003ca href=\"http:\/\/www.informatics.jax.org\/marker\/MGI:103556\"\u003e103556\u003c\/a\u003e \u003c\/p\u003e \u003cp\u003e NOT FOR HUMAN USE! \u003c\/p\u003e \u003cp\u003e \u003cstrong\u003eAdditional resources for this protein may be found at:\u003c\/strong\u003e \u003cbr\u003e \u003ca href=\"http:\/\/www.omim.org\/entry\/600835\"\u003eOMIM\u003c\/a\u003e \u003cbr\u003e \u003c\/p\u003e","brand":"GoldBio","offers":[{"title":"10 μg","offer_id":44854834954297,"sku":"2310-12B-10","price":278.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0718\/5235\/9737\/files\/2310-12B_20structure.jpg?v=1757447791"},{"product_id":"cxcl12-alpha-murine","title":"CXCL12-alpha, Murine","description":"\u003cp\u003e \u003cstrong\u003eGoldBio growth factors are manufactured for RESEARCH USE ONLY and cannot be sold for human consumption!\u003c\/strong\u003e \u003c\/p\u003e \u003cp\u003e Recombinant  Murine Chemokine (C-X-C motif) Ligand 12, Alpha (CXCL12α) \u003cbr\u003e Stromal  Cell-Derived Factor 1 (SDF1) \u003cbr\u003e Small  Inducible Cytokine Subfamily B Member 12 (SCYB12) \u003cbr\u003e Pre-B Cell  Growth-Stimulating Factor (PBSF) \u003cbr\u003e Thymic Lymphoma  Cell-Stimulating Factor (TLSF) \u003c\/p\u003e \u003cp\u003e CXCL12 is a CXC chemokine lacking the ELR motif. It was first found in bone marrow stromal cells and is expressed in bone marrow stromal cells constitutively, as well as a wide variety of other cells with the exception of blood cells. CXCL12 acts as a ligand for CXCR4 and CXCR7. It is chemotactic for hematopoietic progenitor cells expressing CD34, mononuclear cells, and cerebellar granule cells. CXCL12 plays a role in lymphopoiesis, myelopoiesis, vascularization of the gastrointestinal tract, and cerebellar development. CXCL12-alpha is one of six alternatively spliced isoforms of the CXCL12 gene. It is four amino acids shorter at the C-terminus than the canonical sequence, CXCL12-beta. \u003c\/p\u003e \u003cp\u003e Sterile Filtered White lyophilized powder. Purified and tested for use in cell culture. \u003c\/p\u003e \u003cp\u003e Source:\u003cem\u003e Escherichia coli\u003c\/em\u003e \u003c\/p\u003e \u003cp\u003e MW: ~8.0 kDa (68 amino  acids) \u003c\/p\u003e \u003cp\u003e Purity: \u0026gt;97% by SDS-PAGE  and HPLC analyses \u003c\/p\u003e \u003cp\u003e Biological Activity: Fully biologically  active when compared to standard. The biological activity determined by a  chemotaxis bioassay using human peripheral blood monocytes is in a concentration  range of 50-100 ng\/ml. \u003c\/p\u003e \u003cp\u003e Storage\/Handling: Store desiccated at  -20°C. \u003c\/p\u003e \u003cp\u003e MGD: \u003ca href=\"http:\/\/www.informatics.jax.org\/marker\/MGI:103556\"\u003e103556\u003c\/a\u003e \u003c\/p\u003e \u003cp\u003e NOT FOR HUMAN USE! \u003c\/p\u003e \u003cp\u003e \u003cstrong\u003eAdditional resources for this protein may be found at:\u003c\/strong\u003e \u003cbr\u003e \u003ca href=\"http:\/\/www.omim.org\/entry\/600835\"\u003eOMIM\u003c\/a\u003e \u003cbr\u003e \u003c\/p\u003e","brand":"GoldBio","offers":[{"title":"10 μg","offer_id":44854834987065,"sku":"2310-12A-10","price":278.0,"currency_code":"USD","in_stock":true},{"title":"100 μg","offer_id":44854835019833,"sku":"2310-12A-100","price":1254.0,"currency_code":"USD","in_stock":true},{"title":"500 μg","offer_id":44854835052601,"sku":"2310-12A-500","price":2589.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0718\/5235\/9737\/files\/2310-12A_20structure.jpg?v=1757447796"},{"product_id":"cxcl10-murine","title":"CXCL10, Murine","description":"\u003cp\u003e \u003cstrong\u003eGoldBio growth factors are manufactured for RESEARCH USE ONLY and cannot be sold for human consumption!\u003c\/strong\u003e \u003c\/p\u003e \u003cp\u003e Recombinant  Murine Chemokine (C-X-C motif) Ligand 10 (CXCL10) \u003cbr\u003e Cytokine  Responsive Gene 2 (CRG2) \u003cbr\u003e Small Inducible  Cytokine Subfamily B Member 10 (SCYB10) \u003cbr\u003e Interferon  Gamma Inducible Protein 10, (IP10, INP10) \u003c\/p\u003e \u003cp\u003e CXCL10 is a CXC chemokine lacking the ELR motif. It is closely related to CXCL9 and CXCL11, all three of which are ligands for CXCLR3. CXCL10 is expressed in and secreted by monocytes, endothelial cells, fibroblasts, and other cell types after induction by IFNG. CXCL10 is chemotactic for monocytes and T-cell lymphocytes. It plays a role in angiostasis, inhibits bone marrow colony formation, and promotes T-cell adhesion to endothelial cells. CXCL10 also exhibits antimicrobial properties against Gram-positive and Gram-negative bacteria. Knock-out mice have immune system abnormalities, including defective proliferation of T–cells, resulting in increased susceptibility to autoimmune disease and viral infections. Increased expression of CXCL10 and CXCR3 is associated with autoimmune myasthenia gravis. \u003c\/p\u003e \u003cp\u003e Sterile Filtered White lyophilized powder. Purified and tested for use in cell culture. \u003c\/p\u003e \u003cp\u003e Source: \u003cem\u003e Escherichia coli\u003c\/em\u003e \u003c\/p\u003e \u003cp\u003e MW: ~8.7 kDa (77 amino  acids) \u003c\/p\u003e \u003cp\u003e Purity: \u0026gt;97% by SDS-PAGE  and HPLC analyses \u003c\/p\u003e \u003cp\u003e Biological Activity: Fully biologically  active when compared to standard. The biological activity determined by a  chemotaxis bioassay using human peripheral blood lymphocytes is in a  concentration range of 0.1-10 ng\/ml. \u003c\/p\u003e \u003cp\u003e Storage\/Handling: Store desiccated at  -20°C. \u003c\/p\u003e \u003cp\u003e MGD: \u003ca href=\"http:\/\/www.informatics.jax.org\/marker\/MGI:1352450\"\u003e1352450\u003c\/a\u003e \u003c\/p\u003e \u003cp\u003e NOT FOR HUMAN USE! \u003c\/p\u003e \u003cp\u003e \u003cstrong\u003eAdditional resources for this protein may be found at:\u003c\/strong\u003e \u003cbr\u003e \u003ca href=\"http:\/\/www.omim.org\/entry\/147310\"\u003eOMIM\u003c\/a\u003e \u003cbr\u003e \u003c\/p\u003e","brand":"GoldBio","offers":[{"title":"5 μg","offer_id":44854835118137,"sku":"2310-10-5","price":195.0,"currency_code":"USD","in_stock":true},{"title":"100 μg","offer_id":44854835150905,"sku":"2310-10-100","price":1254.0,"currency_code":"USD","in_stock":true},{"title":"500 μg","offer_id":44854835183673,"sku":"2310-10-500","price":2589.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0718\/5235\/9737\/files\/2310-10_20structure.jpg?v=1757447797"},{"product_id":"cxcl9-murine","title":"CXCL9, Murine","description":"\u003cp\u003e \u003cstrong\u003eGoldBio growth factors are manufactured for RESEARCH USE ONLY and cannot be sold for human consumption!\u003c\/strong\u003e \u003c\/p\u003e \u003cp\u003e Recombinant  Murine Chemokine [C-X-C motif] Ligand 9 (CXCL9) \u003cbr\u003e Monokine  Induced by Gamma-Interferon (MIG) \u003cbr\u003e Cytokine  Responsive Gene 10 (CRG10) \u003cbr\u003e Small  Inducible Cytokine Subfamily B Member 9 (SCYB9) \u003cbr\u003e Mumig \u003c\/p\u003e \u003cp\u003e Murine CXCL9 is a CXC chemokine lacking the ELR motif. It is expressed in and secreted by macrophages, epithelial cells, and other cell types after induction by IFNG. It is chemotactic for stimulated T lymphocytes and plays a role in angiostasis, inhibition of neovascularization, inhibition of hematopoietic progenitor cells, and T-cell activation. CXCL9 is most closely related to CXCL10 and CXCL11, all three of which are ligands for CXCLR3. CXCL9 exhibits antimicrobial activity and even after degradation by speB from S. pyogenes, it retains such activity. \u003c\/p\u003e \u003cp\u003e Sterile Filtered White lyophilized powder. Purified and tested for use in cell culture. \u003c\/p\u003e \u003cp\u003e Source: \u003cem\u003eEscherichia coli\u003c\/em\u003e \u003c\/p\u003e \u003cp\u003e MW: ~12.2 kDa (105  amino acids) \u003c\/p\u003e \u003cp\u003e Purity: \u0026gt;95% by SDS-PAGE  and HPLC analyses \u003c\/p\u003e \u003cp\u003e Biological Activity: Fully biologically  active when compared to standard. The biological activity determined by a chemotaxis  bioassay using human lymphocytes is in a concentration range of 0.1-10 ng\/ml. \u003c\/p\u003e \u003cp\u003e Storage\/Handling: Store desiccated at  -20°C. \u003c\/p\u003e \u003cp\u003e MGD: \u003ca href=\"http:\/\/www.informatics.jax.org\/marker\/MGI:1352449\"\u003e1352449\u003c\/a\u003e \u003c\/p\u003e \u003cp\u003e NOT FOR HUMAN USE! \u003c\/p\u003e \u003cp\u003e \u003cstrong\u003eAdditional resources for this protein may be found at:\u003c\/strong\u003e \u003cbr\u003e \u003ca href=\"http:\/\/www.omim.org\/entry\/601704\"\u003eOMIM\u003c\/a\u003e \u003cbr\u003e \u003c\/p\u003e","brand":"GoldBio","offers":[{"title":"5 μg","offer_id":44854835249209,"sku":"2310-09-5","price":195.0,"currency_code":"USD","in_stock":true},{"title":"100 μg","offer_id":44854835281977,"sku":"2310-09-100","price":1254.0,"currency_code":"USD","in_stock":true},{"title":"500 μg","offer_id":44854835314745,"sku":"2310-09-500","price":2589.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0718\/5235\/9737\/files\/Default_No_Image_Bottle_png.png?v=1757612830"},{"product_id":"cxcl5-70-aa-murine","title":"CXCL5 (70 a.a.), Murine","description":"\u003cp\u003e \u003cstrong\u003eGoldBio growth factors are manufactured for RESEARCH USE ONLY and cannot be sold for human consumption!\u003c\/strong\u003e \u003c\/p\u003e \u003cp\u003e Recombinant  Murine Chemokine (C-X-C motif) Ligand 5 (CXCL5) \u003cbr\u003e Epithelial-derived  Neutrophil Activating Peptide 78 (ENA78, ENA-78) \u003cbr\u003e Lipopolysaccharide  (LPS) Induced CXC Chemokine (LIX) \u003cbr\u003e Small  Inducible Cytokine Subfamily B Member 5 (SCYB5) \u003cbr\u003e Murine  Granulocyte Chemotactic Protein 2 (GCP2, GCP-2) \u003cbr\u003e Alveolar  Macrophage Chemotactic Factor 2 (AMCF2, AMCF-2) \u003c\/p\u003e \u003cp\u003e Murine CXCL5 is an ELR type of CXC chemokine. It is expressed in various epithelial cell lines alongside CXCL8 (IL8) and CXCL1 in response to stimulation by IL1 or TNF-alpha. It is downregulated by IFNG. CXCL5 is a ligand for CXCR2 and CXCR1. It is a chemoattractant and activator of neutrophils, and plays a role in angiogenesis and inflammation, as well as the metastasis of various cancers. It also blocks insulin signaling by activating the JAK2\/STAT5\/SOCS2 pathway. Murine CXCL5 is an ortholog of human CXCL6 and is a more potent chemoattractant than human CXCL5 or CXCL6 on human neutrophils. The truncated forms of CXCL5 have been reported as being much more potent than the full length polypeptide. \u003c\/p\u003e \u003cp\u003e Sterile Filtered White lyophilized powder. Purified and tested for use in cell culture. \u003c\/p\u003e \u003cp\u003e Source: \u003cem\u003eEscherichia coli\u003c\/em\u003e \u003c\/p\u003e \u003cp\u003e MW: ~7.6 kDa (70 amino  acids) \u003c\/p\u003e \u003cp\u003e Purity: \u0026gt;96% by SDS-PAGE  and HPLC analyses \u003c\/p\u003e \u003cp\u003e Biological Activity: Fully biologically  active when compared to standard. The biological activity determined by a  chemotaxis bioassay using human peripheral blood neutrophils is in a  concentration of 10-100 ng\/ml. \u003c\/p\u003e \u003cp\u003e Storage\/Handling: Store desiccated at  -20°C. \u003c\/p\u003e \u003cp\u003e MGD: \u003ca href=\"http:\/\/www.informatics.jax.org\/marker\/MGI:1096868\"\u003e1096868\u003c\/a\u003e \u003c\/p\u003e \u003cp\u003e NOT FOR HUMAN USE! \u003c\/p\u003e \u003cp\u003e \u003cstrong\u003eAdditional resources for this protein may be found at:\u003c\/strong\u003e \u003cbr\u003e \u003ca href=\"http:\/\/www.omim.org\/entry\/600324\"\u003eOMIM\u003c\/a\u003e \u003cbr\u003e \u003c\/p\u003e","brand":"GoldBio","offers":[{"title":"5 μg","offer_id":44854835347513,"sku":"2310-05T-5","price":195.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0718\/5235\/9737\/files\/2310-05T_20structure.jpg?v=1757447797"}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0718\/5235\/9737\/collections\/Interleukins_-_IFN-Lambda1_IL29_-_1160-07_structure_fa23afff-ba41-4cc5-99ac-ee20ec390d3b.jpg?v=1769622106","url":"https:\/\/www.goldbio.com\/collections\/all-recombinant-proteins-cytokines.oembed","provider":"GoldBio","version":"1.0","type":"link"}