CSF2 (GM-CSF), Human
GoldBio growth factors are manufactured for RESEARCH USE ONLY and cannot be sold for human consumption!
Recombinant Human Colony Stimulating Factor 2 (granulocyte-macrophage)
MGI-1GM (Macrophage granulocyte inducer-1GM)
Colony Stimulating Factor 2 (GM-CSF) was initially characterized as a growth factor that can support the in vitro colony formation of granulocyte-macrophage progenitors. It is produced by a number of different cell types, including activated T cells, B cells, macrophages, mast cells, endothelial cells and fibroblasts, in response to cytokine or immune and inflammatory stimuli. CSF2 is also a growth factor for erythroid, megakaryocyte and eosinophil progenitors. On mature hematopoietic cells, CSF2 is a survival factor for and activates the effector functions of granulocytes, monocytes/macrophages and eosinophils. It can induce human endothelial cells to migrate and proliferate and can also stimulate the proliferation of a number of tumor cell lines, including osteogenic sarcoma, carcinoma and adenocarcinoma cell lines. CSF2 is species specific and human CSF2 has no biological effects on mouse cells.
Sterile Filtered White lyophilized powder. Purified and tested for use in cell culture.
Source: Escherichia coli
MW: ~14.6 kDa (128 amino acid)
Purity: >96% by SDS-PAGE and HPLC analyses
Storage/Handling: Store desiccated at -20°C.
HGNC ID: 2434
NOT FOR HUMAN USE!Cross-species homology
Additional resources for this protein may be found at:
|Storage/Handling||Store desiccated at -20°C.|