Enzymes are important biological macromolecules that allow for the control of cellular functions and are vital for effective research. Enzyme activity can be slowed or stopped using inhibitors, like Proteinase K or RNase, while substrates like X-Gluc and X-Gal are used in detection and monitoring. D-Luciferin Potassium Salt, our most popular bioluminescent substrate, can be used for in vivo and in vitro imaging. GoldBio knows that having high quality enzyme tools are important to your laboratory, and we are committed to delivering quality products at a fraction of the price.
" ["hide"]=> int(1) ["third_party_id"]=> NULL ["featured_image_id"]=> int(0) ["banner_image_id"]=> int(0) ["meta_description"]=> string(156) "GoldBio carries a huge variety of quality enzymes, inhibitors and substrates, like luciferin, X-Gal and many more to perfectly suit for your research needs." ["meta_keywords"]=> string(0) "" ["root_sort"]=> int(0) ["type"]=> string(7) "product" ["condition_type"]=> int(1) ["condition_match_type"]=> int(1) ["sort_type"]=> int(1) ["items_per_page"]=> int(25) ["color"]=> NULL } ["_oldAttributes":"yii\db\BaseActiveRecord":private]=> array(23) { ["id"]=> int(200) ["root"]=> int(393) ["lft"]=> int(50) ["rgt"]=> int(51) ["level"]=> int(1) ["name"]=> string(38) "Enzymes, Inhibitors & Substrates (old)" ["url_name"]=> string(30) "enzymes-inhibitors-substrates2" ["title"]=> NULL ["short_description"]=> string(0) "" ["long_description"]=> string(675) "Enzymes are important biological macromolecules that allow for the control of cellular functions and are vital for effective research. Enzyme activity can be slowed or stopped using inhibitors, like Proteinase K or RNase, while substrates like X-Gluc and X-Gal are used in detection and monitoring. D-Luciferin Potassium Salt, our most popular bioluminescent substrate, can be used for in vivo and in vitro imaging. GoldBio knows that having high quality enzyme tools are important to your laboratory, and we are committed to delivering quality products at a fraction of the price.
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} [1]=> string(11) "afterInsert" } [1]=> NULL } } ["beforeUpdate"]=> array(1) { [0]=> array(2) { [0]=> array(2) { [0]=> object(creocoder\nestedsets\NestedSetsBehavior)#443 (8) { ["treeAttribute"]=> string(4) "root" ["leftAttribute"]=> string(3) "lft" ["rightAttribute"]=> string(3) "rgt" ["depthAttribute"]=> string(5) "level" ["operation":protected]=> NULL ["node":protected]=> NULL ["owner"]=> *RECURSION* ["_attachedEvents":"yii\base\Behavior":private]=> array(6) { ["beforeInsert"]=> string(12) "beforeInsert" ["afterInsert"]=> string(11) "afterInsert" ["beforeUpdate"]=> string(12) "beforeUpdate" ["afterUpdate"]=> string(11) "afterUpdate" ["beforeDelete"]=> string(12) "beforeDelete" ["afterDelete"]=> string(11) "afterDelete" } } [1]=> string(12) "beforeUpdate" } [1]=> NULL } } ["afterUpdate"]=> array(1) { [0]=> array(2) { [0]=> array(2) { [0]=> object(creocoder\nestedsets\NestedSetsBehavior)#443 (8) { ["treeAttribute"]=> string(4) "root" ["leftAttribute"]=> string(3) "lft" 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NULL } } } ["_eventWildcards":"yii\base\Component":private]=> array(0) { } ["_behaviors":"yii\base\Component":private]=> array(1) { ["tree"]=> object(creocoder\nestedsets\NestedSetsBehavior)#443 (8) { ["treeAttribute"]=> string(4) "root" ["leftAttribute"]=> string(3) "lft" ["rightAttribute"]=> string(3) "rgt" ["depthAttribute"]=> string(5) "level" ["operation":protected]=> NULL ["node":protected]=> NULL ["owner"]=> *RECURSION* ["_attachedEvents":"yii\base\Behavior":private]=> array(6) { ["beforeInsert"]=> string(12) "beforeInsert" ["afterInsert"]=> string(11) "afterInsert" ["beforeUpdate"]=> string(12) "beforeUpdate" ["afterUpdate"]=> string(11) "afterUpdate" ["beforeDelete"]=> string(12) "beforeDelete" ["afterDelete"]=> string(11) "afterDelete" } } } ["__fieldGroups":protected]=> array(0) { } }Bioluminescence is the production and emission of light by a living organism. Bioluminescence occurs widely in marine vertebrates and invertebrates, as well as in some fungi, microorganisms and terrestrial invertebrates. Luciferin, the firefly substrate of luciferase, is a common reagent used throughout the biotechnology field. The injection of luciferin allows for the real-time, noninvasive monitoring of disease progression and/or drug efficacy in these model systems through Bioluminescence Imaging (BLI). Coelenterazine is a luminophore is the substrate for many luciferase enzymes, including Renilla reniformis, gaussia, and aequorins. It is commonly used to monitor reporter genes in BRET (Bioluminescence Resonance Energy Transfer), ELISA and HTS methods. Gold Biotechnology’s luciferin and coelenterazine are Proven and Published™ to ensure a quality reagent with optimal potential.
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NULL } } } ["_eventWildcards":"yii\base\Component":private]=> array(0) { } ["_behaviors":"yii\base\Component":private]=> array(1) { ["tree"]=> object(creocoder\nestedsets\NestedSetsBehavior)#449 (8) { ["treeAttribute"]=> string(4) "root" ["leftAttribute"]=> string(3) "lft" ["rightAttribute"]=> string(3) "rgt" ["depthAttribute"]=> string(5) "level" ["operation":protected]=> NULL ["node":protected]=> NULL ["owner"]=> *RECURSION* ["_attachedEvents":"yii\base\Behavior":private]=> array(6) { ["beforeInsert"]=> string(12) "beforeInsert" ["afterInsert"]=> string(11) "afterInsert" ["beforeUpdate"]=> string(12) "beforeUpdate" ["afterUpdate"]=> string(11) "afterUpdate" ["beforeDelete"]=> string(12) "beforeDelete" ["afterDelete"]=> string(11) "afterDelete" } } } ["__fieldGroups":protected]=> array(0) { } }DMNPE-caged Luciferin
Product Description
Tested and Certified for in vivo imaging (See "Luciferin FAQ" in additional information)
Luciferin is a common bioluminescent reporter used for in vivo imaging of the expression of the luciferase . This substrate for the firefly luciferase enzyme utilizes ATP and Mg2+ as cofactors and emits a characteristic yellow-green emission in the presence of oxygen, which shifts to red light in vivo at 37°C.
Luciferin is a common reagent used throughout the biotechnology field and specifically for in vivo imaging. Luciferase labeled tumor cells, stem cells or infectious diseases are often inoculated into research animals such as rats or mice for investigation. The injection of luciferin allows for the real-time, noninvasive monitoring of disease progression and/or drug efficacy in these model systems through Bioluminescence Imaging (BLI).
DMNPE-caged luciferin can be used to measure intracellular functions since it readily crosses cell membranes. Once it is inside the cell, active luciferin can be released by UV light or by the action of endogenous intracellular esterases. DMNPE-caged luciferin makes it easier to follow the changes in gene expression in live cells. It can also be used in combination with DMNPE-caged ATP.
Product Specifications:
DMNPE-caged Luciferin
D-Luciferin 1- (4,5-dimethoxy-2- nitrophenyl) ethyl ester
MOLECULAR BIOLOGY GRADE
Color: Light yellow powder
Formula: C21H19N3O7S2
MW: 489.53 g/mol
Soluble in DMSO or DMF.
Storage: Store desiccated at -20°C, protect from light.
PubChem CID: 2762658
Product Specifications
Catalog ID | L-130 |
---|---|
CAS # | 223920-67-0 |
MW | 489.53 g/mol |
Grade | MOLECULAR BIOLOGY GRADE |
Storage/Handling | Store desiccated at -20°C. Protect from light. |
Technical Documentation
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