Spectinomycin Dihydrochloride Pentahydrate 100 mg/mL Solution
Spectinomycin is an aminocyclitol antibiotic isolated from Streptomyces spectabilis. It is effective against gram-positive and gram-negative bacteria, but most commonly used against Gonococcus species. It has also been used to monitor cell fate during leaf development and as a selection marker in plants to display successful transformation of the Spcr gene.
Spectinomycin functions by binding the 30s ribosomal subunit, inhibiting tRNA translation and protein synthesis. Resistance to this antibiotic is conferred through the aadA gene and mutated rpsE gene.
GoldBio’s antibiotic solutions are provided ready to use.
Spectinomycin Dihydrochloride Pentahydrate in H2O
(100 mg/mL Premade Solution, 0.2 µm Sterile Filtered)
Formula: C14H24N2O7 · 2HCl · 5H2O
MW: 495.35 g/mol
Storage/Handling: Store at -20°C.
PubChem Chemical ID: 30971
A brief explanation of the disk diffusion assay method used to test Gold Bio antibiotics
Tobacco Plasmid Transformation using Spectinomycin, by Khan and Maliga (1999)