• object(anvilstl\commercio\models\Category)#413 (15) { ["featured_image_urls"]=> array(0) { } ["featured_image"]=> array(0) { } ["banner_image_urls"]=> array(0) { } ["productCount"]=> NULL ["_attributes":"yii\db\BaseActiveRecord":private]=> array(23) { ["id"]=> int(66) ["root"]=> int(1) ["lft"]=> int(100) ["rgt"]=> int(131) ["level"]=> int(3) ["name"]=> string(11) "Antibiotics" ["url_name"]=> string(11) "antibiotics" ["title"]=> NULL ["short_description"]=> string(0) "" ["long_description"]=> string(701) "

    Gold Biotechnology offers more than 200 unique antibiotic agents for use in a wide variety of cell culture, microbiology and molecular biology applications. Antibiotic agents are often clinically used to inhibit bacterial growth or kill bacteria as selection markers in agar or liquid media. The first commercially available antibiotics were developed in the 1930s, starting with the sulfonamides in 1932 and exploded later with the discovery of penicillin in 1942. Gold Biotechnology’s antibiotics cover 14 classes, including aminoglycosides, carbapenems, macrolides, penicillins, quinolones, sulfonamides and tetracyclines, as well as multiple generations of cephalosporin antibiotics.

    " ["hide"]=> int(0) ["third_party_id"]=> int(36) ["featured_image_id"]=> int(0) ["banner_image_id"]=> int(0) ["meta_description"]=> string(146) "GoldBio carries more than 150 quality research antibiotics, including a variety of aminoglycosides, glycopeptides, cephalosporins and penicillins." ["meta_keywords"]=> string(0) "" ["root_sort"]=> int(0) ["type"]=> string(7) "product" ["condition_type"]=> int(1) ["condition_match_type"]=> int(1) ["sort_type"]=> int(1) ["items_per_page"]=> int(25) ["color"]=> string(21) "rgba(245, 166, 35, 1)" } ["_oldAttributes":"yii\db\BaseActiveRecord":private]=> array(23) { ["id"]=> int(66) ["root"]=> int(1) ["lft"]=> int(100) ["rgt"]=> int(131) ["level"]=> int(3) ["name"]=> string(11) "Antibiotics" ["url_name"]=> string(11) "antibiotics" ["title"]=> NULL ["short_description"]=> string(0) "" ["long_description"]=> string(701) "

    Gold Biotechnology offers more than 200 unique antibiotic agents for use in a wide variety of cell culture, microbiology and molecular biology applications. Antibiotic agents are often clinically used to inhibit bacterial growth or kill bacteria as selection markers in agar or liquid media. The first commercially available antibiotics were developed in the 1930s, starting with the sulfonamides in 1932 and exploded later with the discovery of penicillin in 1942. Gold Biotechnology’s antibiotics cover 14 classes, including aminoglycosides, carbapenems, macrolides, penicillins, quinolones, sulfonamides and tetracyclines, as well as multiple generations of cephalosporin antibiotics.

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  • object(anvilstl\commercio\models\Category)#440 (15) { ["featured_image_urls"]=> array(0) { } ["featured_image"]=> array(0) { } ["banner_image_urls"]=> array(0) { } ["productCount"]=> NULL ["_attributes":"yii\db\BaseActiveRecord":private]=> array(23) { ["id"]=> int(76) ["root"]=> int(1) ["lft"]=> int(121) ["rgt"]=> int(122) ["level"]=> int(4) ["name"]=> string(11) "Penicillins" ["url_name"]=> string(11) "penicillins" ["title"]=> NULL ["short_description"]=> string(0) "" ["long_description"]=> string(742) "Penicillins are a group of antibacterial agents derived from the Penicillium fungus and includes penicillin G, penicillin V, ampicillin and carbenicillin. Penicillins are β-lactams, which interfere with PBP (Penicillin Binding Protein) activity involved in the final phase of peptidoglycan synthesis. PBPs are enzymes that catalyze a pentaglycine cross-link between alanine and lysine residues providing additional strength to the cell wall. Without a pentaglycine cross-link, the integrity of the cell wall is severely compromised and ultimately leads to cell lysis and death. Many penicillins, such as ampicillin, amoxicillin and carbenicillin, are commonly used as selective agents in laboratory, bacterial screening protocols." ["hide"]=> int(0) ["third_party_id"]=> int(260) ["featured_image_id"]=> int(0) ["banner_image_id"]=> int(0) ["meta_description"]=> string(154) "GoldBio’s catalog of penicillins includes amoxicillin, ampicillin, carbenicillin and more. These penicillins are often used in labs as selective agents." 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Without a pentaglycine cross-link, the integrity of the cell wall is severely compromised and ultimately leads to cell lysis and death. Many penicillins, such as ampicillin, amoxicillin and carbenicillin, are commonly used as selective agents in laboratory, bacterial screening protocols." ["hide"]=> int(0) ["third_party_id"]=> int(260) ["featured_image_id"]=> int(0) ["banner_image_id"]=> int(0) ["meta_description"]=> string(154) "GoldBio’s catalog of penicillins includes amoxicillin, ampicillin, carbenicillin and more. These penicillins are often used in labs as selective agents." 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  • object(anvilstl\commercio\models\Category)#442 (15) { ["featured_image_urls"]=> array(0) { } ["featured_image"]=> array(0) { } ["banner_image_urls"]=> array(0) { } ["productCount"]=> NULL ["_attributes":"yii\db\BaseActiveRecord":private]=> array(23) { ["id"]=> int(197) ["root"]=> int(393) ["lft"]=> int(28) ["rgt"]=> int(29) ["level"]=> int(1) ["name"]=> string(39) "Protein Expression & Purification (old)" ["url_name"]=> string(32) "protein-expression-purification2" ["title"]=> NULL ["short_description"]=> string(0) "" ["long_description"]=> string(484) "

    Proteins are fundamental macromolecules found in every biological system and form the basis of many fields of work from research into drug creation to industrial applications like fermentation. GoldBio protein products are ideal for every step of your protein synthesis. Our reagents and tools are of the highest quality available at a fraction of the prices of other vendors, so you can be assured that your research yields confident results without compromising your budget.

    " ["hide"]=> int(1) ["third_party_id"]=> NULL ["featured_image_id"]=> int(0) ["banner_image_id"]=> int(0) ["meta_description"]=> string(105) "GoldBio protein expression and purification products ensure high-quality proteins at an affordable price." ["meta_keywords"]=> string(0) "" ["root_sort"]=> int(9) ["type"]=> string(7) "product" ["condition_type"]=> int(1) ["condition_match_type"]=> int(1) ["sort_type"]=> int(1) ["items_per_page"]=> int(25) ["color"]=> NULL } ["_oldAttributes":"yii\db\BaseActiveRecord":private]=> array(23) { ["id"]=> int(197) ["root"]=> int(393) ["lft"]=> int(28) ["rgt"]=> int(29) ["level"]=> int(1) ["name"]=> string(39) "Protein Expression & Purification (old)" ["url_name"]=> string(32) "protein-expression-purification2" ["title"]=> NULL ["short_description"]=> string(0) "" ["long_description"]=> string(484) "

    Proteins are fundamental macromolecules found in every biological system and form the basis of many fields of work from research into drug creation to industrial applications like fermentation. GoldBio protein products are ideal for every step of your protein synthesis. Our reagents and tools are of the highest quality available at a fraction of the prices of other vendors, so you can be assured that your research yields confident results without compromising your budget.

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  • object(anvilstl\commercio\models\Category)#444 (15) { ["featured_image_urls"]=> array(0) { } ["featured_image"]=> array(0) { } ["banner_image_urls"]=> array(0) { } ["productCount"]=> NULL ["_attributes":"yii\db\BaseActiveRecord":private]=> array(23) { ["id"]=> int(206) ["root"]=> int(1) ["lft"]=> int(322) ["rgt"]=> int(331) ["level"]=> int(3) ["name"]=> string(28) "Cell Selection & Maintenance" ["url_name"]=> string(26) "cell-selection-maintenance" ["title"]=> NULL ["short_description"]=> string(0) "" ["long_description"]=> string(661) "As you go through the process of selecting and maintaining your cell lines for downstream research, GoldBio wants to provide you with the quality tools you need to effectively analyze, induce and isolate your protein samples. With hundreds of high quality antibiotics like ampicillin and hygromycin, the most affordable IPTG on the market, the essentials of electrophoretic reagents and our famously robust DNA ladders and agarose, GoldBio is determined to cover your research needs from selection to expression. Take time to browse these important mainstays of molecular biology from a company known for its commitment to affordability and exceptional quality." ["hide"]=> int(0) ["third_party_id"]=> NULL ["featured_image_id"]=> int(0) ["banner_image_id"]=> int(0) ["meta_description"]=> string(95) "GoldBio offers affordable, quality tools to perform a variety of protein analytical procedures." ["meta_keywords"]=> string(0) "" ["root_sort"]=> int(0) ["type"]=> string(7) "product" ["condition_type"]=> int(1) ["condition_match_type"]=> int(1) ["sort_type"]=> int(1) ["items_per_page"]=> int(25) ["color"]=> NULL } ["_oldAttributes":"yii\db\BaseActiveRecord":private]=> array(23) { ["id"]=> int(206) ["root"]=> int(1) ["lft"]=> int(322) ["rgt"]=> int(331) ["level"]=> int(3) ["name"]=> string(28) "Cell Selection & Maintenance" ["url_name"]=> string(26) "cell-selection-maintenance" ["title"]=> NULL ["short_description"]=> string(0) "" ["long_description"]=> string(661) "As you go through the process of selecting and maintaining your cell lines for downstream research, GoldBio wants to provide you with the quality tools you need to effectively analyze, induce and isolate your protein samples. With hundreds of high quality antibiotics like ampicillin and hygromycin, the most affordable IPTG on the market, the essentials of electrophoretic reagents and our famously robust DNA ladders and agarose, GoldBio is determined to cover your research needs from selection to expression. Take time to browse these important mainstays of molecular biology from a company known for its commitment to affordability and exceptional quality." ["hide"]=> int(0) ["third_party_id"]=> NULL ["featured_image_id"]=> int(0) ["banner_image_id"]=> int(0) ["meta_description"]=> string(95) "GoldBio offers affordable, quality tools to perform a variety of protein analytical procedures." 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With 14 classes and over 150 to choose from, including popular choices like Hygromycin B, Ampicillin and G-418, GoldBio antibiotics are the right choice for your research every time." ["hide"]=> int(0) ["third_party_id"]=> NULL ["featured_image_id"]=> int(0) ["banner_image_id"]=> int(0) ["meta_description"]=> string(100) "GoldBio most popular antibiotics are affordable ways to purify your modified cell line for analysis." 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With 14 classes and over 150 to choose from, including popular choices like Hygromycin B, Ampicillin and G-418, GoldBio antibiotics are the right choice for your research every time." ["hide"]=> int(0) ["third_party_id"]=> NULL ["featured_image_id"]=> int(0) ["banner_image_id"]=> int(0) ["meta_description"]=> string(100) "GoldBio most popular antibiotics are affordable ways to purify your modified cell line for analysis." 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  • object(anvilstl\commercio\models\Category)#452 (15) { ["featured_image_urls"]=> array(3) { ["small"]=> string(90) "https://s3.amazonaws.com/commercio/goldbio-2018/collection/small/Antibiotics-Selection.jpg" ["medium"]=> string(91) "https://s3.amazonaws.com/commercio/goldbio-2018/collection/medium/Antibiotics-Selection.jpg" ["large"]=> string(90) "https://s3.amazonaws.com/commercio/goldbio-2018/collection/large/Antibiotics-Selection.jpg" } ["featured_image"]=> array(3) { ["small"]=> string(90) "https://s3.amazonaws.com/commercio/goldbio-2018/collection/small/Antibiotics-Selection.jpg" ["medium"]=> string(91) "https://s3.amazonaws.com/commercio/goldbio-2018/collection/medium/Antibiotics-Selection.jpg" ["large"]=> string(90) "https://s3.amazonaws.com/commercio/goldbio-2018/collection/large/Antibiotics-Selection.jpg" } ["banner_image_urls"]=> array(0) { } ["productCount"]=> NULL ["_attributes":"yii\db\BaseActiveRecord":private]=> array(23) { ["id"]=> int(300) ["root"]=> int(393) ["lft"]=> int(32) ["rgt"]=> int(33) ["level"]=> int(1) ["name"]=> string(29) "Antibiotics & Selection (old)" ["url_name"]=> string(26) "antibiotics-and-selection2" ["title"]=> NULL ["short_description"]=> string(0) "" ["long_description"]=> string(410) "

    Antibiotics and Selection tools allow you to selectively control which cells can be found in your cultures.



    GoldBio’s broad range of cell selection tools, including hundreds of antibiotics, antifungals and anticancers, plant selection and screening agents allow you to select, control and maintain your cell cultures with confidence and ease, no matter what cells you may be studying.

    " ["hide"]=> int(1) ["third_party_id"]=> NULL ["featured_image_id"]=> int(24) ["banner_image_id"]=> int(0) ["meta_description"]=> string(0) "" ["meta_keywords"]=> string(0) "" ["root_sort"]=> int(0) ["type"]=> string(7) "product" ["condition_type"]=> int(1) ["condition_match_type"]=> int(1) ["sort_type"]=> int(1) ["items_per_page"]=> int(25) ["color"]=> string(21) "rgba(244, 140, 14, 1)" } ["_oldAttributes":"yii\db\BaseActiveRecord":private]=> array(23) { ["id"]=> int(300) ["root"]=> int(393) ["lft"]=> int(32) ["rgt"]=> int(33) ["level"]=> int(1) ["name"]=> string(29) "Antibiotics & Selection (old)" ["url_name"]=> string(26) "antibiotics-and-selection2" ["title"]=> NULL ["short_description"]=> string(0) "" ["long_description"]=> string(410) "

    Antibiotics and Selection tools allow you to selectively control which cells can be found in your cultures.



    GoldBio’s broad range of cell selection tools, including hundreds of antibiotics, antifungals and anticancers, plant selection and screening agents allow you to select, control and maintain your cell cultures with confidence and ease, no matter what cells you may be studying.

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"https://s3.amazonaws.com/commercio/goldbio-2018/uploads/images/default/original/Plantlings 2-smaller.jpg" } } [1]=> array(22) { ["id"]=> int(34) ["parent_id"]=> int(0) ["field_group_id"]=> int(4) ["name"]=> string(7) "Caption" ["slug"]=> string(7) "caption" ["placeholder"]=> NULL ["instructions"]=> string(0) "" ["type"]=> string(9) "TextField" ["max_length"]=> NULL ["min_length"]=> NULL ["min"]=> NULL ["max"]=> NULL ["pattern"]=> NULL ["required"]=> int(0) ["field_options"]=> NULL ["auto_complete"]=> NULL ["is_search_aggregation"]=> int(0) ["test"]=> NULL ["position"]=> int(2) ["children"]=> array(0) { } ["fieldChoices"]=> array(0) { } ["value"]=> string(22) "Plant Selection Agents" } [2]=> array(22) { ["id"]=> int(35) ["parent_id"]=> int(0) ["field_group_id"]=> int(4) ["name"]=> string(3) "Url" ["slug"]=> string(3) "url" ["placeholder"]=> NULL ["instructions"]=> string(0) "" ["type"]=> string(8) "UrlField" ["max_length"]=> NULL ["min_length"]=> NULL ["min"]=> NULL ["max"]=> NULL 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    • Timentin™ Ticarcillin/Clavulanate (15/1)

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    Product Description

    Timentin™ is a 15:1 mixture of ticarcillin and clavulanate. Ticarcillin is a penicillin ß-lactam antibiotic, which is susceptible to ß-lactamase degradation. When combined with clavulanate, a ß-lactamase inhibitor, its efficacy is greatly increased. Timentin™ exhibits high activity against gram-negative bacteria and resistant Agrobacterium species.

    Penicillins are a type of β-lactam antibiotic consisting of a four-membered β-lactam ring bound to a five-membered thiazolidine ring. This two-ring system causes distortion of the β-lactam amide bond, resulting in decreased resonance stabilization and increased reactivity. β-lactams inhibit the formation of peptidoglycan cross-links within bacterial cell walls by targeting penicillin-binding proteins or PBPs. Consequently, the bacterial cell wall becomes weak and cytolysis occurs. Resistance to β-lactam antibiotics occurs in the presence of cells containing plasmid encoded extended spectrum β-lactamases or ESBLs.

    Antibiotics are often used in clinical in vitro tests known as antimicrobial susceptibility tests or ASTs to determine their efficacy against certain bacterial species. They are tested against gram-negative and gram-positive bacteria using panels, discs, and MIC strips by medical microbiologists. ASTs decrease the risk of using an antibiotic against bacteria exhibiting resistance to it, and the results are used in clinical settings to determine which antibiotic(s) to prescribe for various infections.

    TESTED AGAINST BOTH SENSITIVE AND RESISTANT CELLS AT GOLD BIOTECHNOLOGY LAB.

    Product Specifications
    Ticarcillin Disodium
    Potassium Clavulanate

    USP GRADE

    Formula: C15H14N2Na2O6S2 / C8H8KNO5

    MW: 665.64 g/mol (combined)

    Storage/Handling: Store desiccated at -20°C. Soluble in water.

    PubChem Chemical ID (Ticarcillin): 470375
    PubChem Chemical ID (Clavulanate): 23665591

    Product Specifications

    Catalog ID T-104
    CAS # 4697-14-7; 61177-45-5
    MW 665.64 g/mol
    Grade MOLECULAR BIOLOGY GRADE
    Storage/Handling Store desiccated at -20°C.

    Technical Documentation

    P Protocol
    O Other
    C Certificate of Analysis
    S Safety Data Sheet
    P
    Antibiotic Testing Procedure

    A brief explanation of the disk diffusion assay method used to test Gold Bio antibiotics
    P
    Potato-Agrobacterium Transformation

    Potato-Agrobacterium Transformation using Kanamycin, Timentin and Zeatin - by Hui Duan et al. (2012)
    P
    Timentin Stock Solution

    Timentin Stock Solution - 100-200 mg/ml
    P
    GoldBio Disk Diffusion Assay Protocol

    Testing an Antibiotic Using a Disk Diffusion Assay
    C
    Sample COA - T-104

    Sample Certificate of Analysis - TimentinTM
    COA for example only. Actual tests may differ.
    S
    SDS (MSDS) - TimentinTM

    Safety Data Sheet

    Citations

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