ATG5 Polyclonal Antibody

Product Description

The protein encoded by this gene, in combination with autophagy protein 12, functions as an E1-like activating enzyme in a ubiquitin-like conjugating system. The encoded protein is involved in several cellular processes, including autophagic vesicle formation, mitochondrial quality control after oxidative damage, negative regulation of the innate antiviral immune response, lymphocyte development and proliferation, MHC II antigen presentation, adipocyte differentiation, and apoptosis. Several transcript variants encoding different protein isoforms have been found for this gene.

Product Name
ATG5 Polyclonal Antibody
ATG5 Rabbit mAb
ATG5; APG5; APG5-LIKE; APG5L; ASP; hAPG5

Host Species
Rabbit

Purification Method
Affinity purification

Isotype
IgG

Storage/Handling
Store at -20℃. Avoid freeze / thaw cycles.

Storage Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Immunogen Information

Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 1-275 of human ATG5 (NP_004840.1).

Sequence
MTDDKDVLRD VWFGRIPTCF TLYQDEITER EAEPYYLLLP RVSYLTLVTD KVKKHFQKVM RQEDISEIWF EYEGTPLKWH YPIGLLFDLL ASSSALPWNI TVHFKSFPEK DLLHCPSKDA IEAHFMSCMK EADALKHKSQ VINEMQKKDH KQLWMGLQND RFDQFWAINR KLMEYPAEEN GFRYIPFRIY QTTTERPFIQ KLFRPVAADG QLHTLGDLLK EVCPSAIDPE DGEKKNQVMI HGIEPMLETP LQWLSEHLSY PDNFLHISII PQPTD

Gene ID: 9474

Swiss Protein: Q9H1Y0

Calculated MW: 22 kDa/32 kDa

Observed MW: 55 kDa

Product Specifications

Catalog ID AB0723
Name ATG5 Polyclonal Antibody
Reactivity Human, Mouse, Rat
Tested Applications WB, IF
Recommended Dilution • WB 1:500 - 1:2000
• IF 1:50 - 1:200
Storage Buffer PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Positive Samples HeLa, NIH/3T3, U-87MG
Cellular Location Cytoplasm, Peripheral membrane protein, Preautophagosomal structure membrane

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