ATG5 Polyclonal Antibody
Product Description
The protein encoded by this gene, in combination with autophagy protein 12, functions as an E1-like activating enzyme in a ubiquitin-like conjugating system. The encoded protein is involved in several cellular processes, including autophagic vesicle formation, mitochondrial quality control after oxidative damage, negative regulation of the innate antiviral immune response, lymphocyte development and proliferation, MHC II antigen presentation, adipocyte differentiation, and apoptosis. Several transcript variants encoding different protein isoforms have been found for this gene.
Product Name
ATG5 Polyclonal Antibody
ATG5 Rabbit mAb
ATG5; APG5; APG5-LIKE; APG5L; ASP; hAPG5
Host Species
Rabbit
Purification Method
Affinity purification
Isotype
IgG
Storage/Handling
Store at -20℃. Avoid freeze / thaw cycles.
Storage Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Immunogen Information
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 1-275 of human ATG5 (NP_004840.1).
Sequence
MTDDKDVLRD VWFGRIPTCF TLYQDEITER EAEPYYLLLP RVSYLTLVTD KVKKHFQKVM RQEDISEIWF EYEGTPLKWH YPIGLLFDLL ASSSALPWNI TVHFKSFPEK DLLHCPSKDA IEAHFMSCMK EADALKHKSQ VINEMQKKDH KQLWMGLQND RFDQFWAINR KLMEYPAEEN GFRYIPFRIY QTTTERPFIQ KLFRPVAADG QLHTLGDLLK EVCPSAIDPE DGEKKNQVMI HGIEPMLETP LQWLSEHLSY PDNFLHISII PQPTD
Gene ID: 9474
Swiss Protein: Q9H1Y0
Calculated MW: 22 kDa/32 kDa
Observed MW: 55 kDaProduct Specifications
| Catalog ID | AB0723 |
|---|---|
| Name | ATG5 Polyclonal Antibody |
| Reactivity | Human, Mouse, Rat |
| Tested Applications | WB, IF |
| Recommended Dilution |
• WB 1:500 - 1:2000 • IF 1:50 - 1:200 |
| Storage Buffer | PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Positive Samples | HeLa, NIH/3T3, U-87MG |
| Cellular Location | Cytoplasm, Peripheral membrane protein, Preautophagosomal structure membrane |
