BMP2 Polyclonal Antibody

Product Description

This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer, which plays a role in bone and cartilage development. Duplication of a regulatory region downstream of this gene causes a form of brachydactyly characterized by a malformed index finger and second toe in human patients.

Product Name
BMP2 Polyclonal Antibody
BMP2 Rabbit pAb
BDA2; BMP2A; BMP2

Host Species
Rabbit

Purification Method
Affinity purification

Isotype
IgG

Storage/Handling
Store at -20℃. Avoid freeze / thaw cycles.

Storage Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Immunogen Information

Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 283-396 of human BMP2 (NP_001191.1).

Sequence
QAKHKQRKRL KSSCKRHPLY VDFSDVGWND WIVAPPGYHA FYCHGECPFP LADHLNSTNH AIVQTLVNSV NSKIPKACCV PTELSAISML YLDENEKVVL KNYQDMVVEG CGCR

Gene ID: 650

Swiss Protein: P12643

Calculated MW: 44 kDa

Observed MW: 45 kDa

Product Specifications

Catalog ID AB0966
Name BMP2 Polyclonal Antibody
Reactivity Human, Mouse, Rat
Tested Applications WB, IHC
Recommended Dilution • WB 1:500 - 1:2000
• IHC 1:50 - 1:100
Storage Buffer PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Positive Samples HeLa, THP-1, PC-12
Cellular Location Secreted

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