c-Fos Polyclonal Antibody
Product Description
The Fos gene family consists of 4 members: FOS, FOSB, FOSL1, and FOSL2. These genes encode leucine zipper proteins that can dimerize with proteins of the JUN family, thereby forming the transcription factor complex AP-1. As such, the FOS proteins have been implicated as regulators of cell proliferation, differentiation, and transformation. In some cases, expression of the FOS gene has also been associated with apoptotic cell death.
Product Name
c-Fos Polyclonal Antibody
c-Fos Rabbit pAb
FOS; AP-1; C-FOS; p55; c-Fos
Host Species
Rabbit
Purification Method
Affinity purification
Isotype
IgG
Storage/Handling
Store at -20℃. Avoid freeze / thaw cycles.
Storage Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Immunogen Information
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 211-380 of human c-Fos (NP_005243.1).
Sequence
GFPEEMSVAS LDLTGGLPEV ATPESEEAFT LPLLNDPEPK PSVEPVKSIS SMELKTEPFD DFLFPASSRP SGSETARSVP DMDLSGSFYA ADWEPLHSGS LGMGPMATEL EPLCTPVVTC TPSCTAYTSS FVFTYPEADS FPSCAAAHRK GSSSNEPSSD SLSSPTLLAL
Gene ID: 2353
Swiss Protein: P01100
Calculated MW: 28 kDa/36 kDa/40 kDa
Observed MW: 62 kDa
Product Specifications
| Catalog ID | AB1648 |
|---|---|
| Name | c-Fos Polyclonal Antibody |
| Reactivity | Human, Mouse, Rat |
| Tested Applications | WB, IHC, IF |
| Recommended Dilution |
• WB 1:500 - 1:2000 • IHC 1:50 - 1:200 • IF 1:50 - 1:200 |
| Storage Buffer | PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Positive Samples | HepG2 |
| Cellular Location | Cytoplasm, Endoplasmic reticulum, Nucleus, cytosol |
