c-Fos Polyclonal Antibody

Product Description

The Fos gene family consists of 4 members: FOS, FOSB, FOSL1, and FOSL2. These genes encode leucine zipper proteins that can dimerize with proteins of the JUN family, thereby forming the transcription factor complex AP-1. As such, the FOS proteins have been implicated as regulators of cell proliferation, differentiation, and transformation. In some cases, expression of the FOS gene has also been associated with apoptotic cell death.

Product Name
c-Fos Polyclonal Antibody
c-Fos Rabbit pAb
FOS; AP-1; C-FOS; p55; c-Fos

Host Species
Rabbit

Purification Method
Affinity purification

Isotype
IgG

Storage/Handling
Store at -20℃. Avoid freeze / thaw cycles.

Storage Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Immunogen Information

Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 211-380 of human c-Fos (NP_005243.1).

Sequence
GFPEEMSVAS LDLTGGLPEV ATPESEEAFT LPLLNDPEPK PSVEPVKSIS SMELKTEPFD DFLFPASSRP SGSETARSVP DMDLSGSFYA ADWEPLHSGS LGMGPMATEL EPLCTPVVTC TPSCTAYTSS FVFTYPEADS FPSCAAAHRK GSSSNEPSSD SLSSPTLLAL

Gene ID: 2353

Swiss Protein: P01100

Calculated MW: 28 kDa/36 kDa/40 kDa

Observed MW: 62 kDa

Product Specifications

Catalog ID AB1648
Name c-Fos Polyclonal Antibody
Reactivity Human, Mouse, Rat
Tested Applications WB, IHC, IF
Recommended Dilution • WB 1:500 - 1:2000
• IHC 1:50 - 1:200
• IF 1:50 - 1:200
Storage Buffer PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Positive Samples HepG2
Cellular Location Cytoplasm, Endoplasmic reticulum, Nucleus, cytosol

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