ABCA1 Polyclonal Antibody

Product Description

The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intracellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ABC1 subfamily. Members of the ABC1 subfamily comprise the only major ABC subfamily found exclusively in multicellular eukaryotes. With cholesterol as its substrate, this protein functions as a cholesteral efflux pump in the cellular lipid removal pathway. Mutations in this gene have been associated with Tangier's disease and familial high-density lipoprotein deficiency.

Product Name
ABCA1 Polyclonal Antibody
ABCA1 Rabbit pAb
ABCA1; ABC-1; ABC1; CERP; HDLDT1; TGD

Host Species
Rabbit

Purification Method
Affinity purification

Isotype
IgG

Storage/Handling
Store at -20℃. Avoid freeze / thaw cycles.

Storage Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Immunogen Information

Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 1870-2120 of human ABCA1 (NP_005493.2).

Sequence
IQYRFFIRPR PVNAKLSPLN DEDEDVRRER QRILDGGGQN DILEIKELTK IYRRKRKPAV DRICVGIPPG ECFGLLGVNG AGKSSTFKML TGDTTVTRGD AFLNKNSILS NIHEVHQNMG YCPQFDAITE LLTGREHVEF FALLRGVPEK EVGKVGEWAI RKLGLVKYGE KYAGNYSGGN KRKLSTAMAL IGGPPVVFLD EPTTGMDPKA RRFLWNCALS VVKEGRSVVL TSHSMEECEA LCTRMAIMVN G

Gene ID: 19
Swiss Protein: O95477

Calculated MW: 254 kDa

Observed MW: 254 kDa

Product Specifications

Catalog ID AB0020
Name ABCA1 Polyclonal Antibody
Reactivity Human, Mouse
Tested Applications WB
Recommended Dilution • WB 1:500 - 1:2000
Storage Buffer PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Positive Samples A-431
Cellular Location Membrane, Multi-pass membrane protein

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