ADAM10 Polyclonal Antibody
Product Description
Members of the ADAM family are cell surface proteins with a unique structure possessing both potential adhesion and protease domains. This gene encodes and ADAM family member that cleaves many proteins including TNF-alpha and E-cadherin. Alternate splicing results in multiple transcript variants encoding different proteins that may undergo similar processing.
Product Name
ADAM10 Polyclonal Antibody
ADAM10 Rabbit pAb
ADAM10; AD10; AD18; CD156c; CDw156; HsT18717; MADM; RAK; kuz
Host Species
Rabbit
Purification Method
Affinity purification
Isotype
IgG
Storage/Handling
Store at -20℃. Avoid freeze / thaw cycles.
Storage Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Immunogen Information
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 214-500 of human ADAM10 (NP_001101.1).
Sequence
TTSAEKNTCQ LYIQTDHLFF KYYGTREAVI AQISSHVKAI DTIYQTTDFS GIRNISFMVK RIRINTTADE KDPTNPFRFP NIGVEKFLEL NSEQNHDDYC LAYVFTDRDF DDGVLGLAWV GAPSGSSGGI CEKSKLYSDG KKKSLNTGII TVQNYGSHVP PKVSHITFAH EVGHNFGSPH DSGTECTPGE SKNLGQKENG NYIMYARATS GDKLNNNKFS LCSIRNISQV LEKKRNNCFV ESGQPICGNG MVEQGEECDC GYSDQCKDEC CFDANQPEGR KCKLKPG
Gene ID: 102
Swiss Protein: O14672
Calculated MW: 49 kDa/84 kDa
Observed MW: 70 kDa/105 kDa
Product Specifications
| Catalog ID | AB0159 |
|---|---|
| Name | ADAM10 Polyclonal Antibody |
| Reactivity | Human, Mouse, Rat |
| Tested Applications | WB, IF |
| Recommended Dilution |
• WB 1:500 - 1:2000 • IF 1:50 - 1:200 |
| Storage Buffer | PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Positive Samples | HT-1080, Raji, Jurkat, Mouse kidney, Mouse brain |
| Cellular Location | Cell membrane, Endomembrane system, Single-pass type I membrane protein |
