Beclin 1 Polyclonal Antibody (KO Validated)

Product Description

This gene encodes a protein that regulates autophagy, a catabolic process of degradation induced by starvation. The encoded protein is a component of the phosphatidylinositol-3-kinase (PI3K) complex which mediates vesicle-trafficking processes. This protein is thought to play a role in multiple cellular processes, including tumorigenesis, neurodegeneration and apoptosis. Alternative splicing results in multiple transcript variants.

Product Name
Beclin 1 Polyclonal Antibody
Beclin 1 Rabbit pAb
ATG6; VPS30; beclin1; Beclin 1; BECN1; beclin-1

Host Species
Rabbit

Purification Method
Affinity purification

Isotype
IgG

Storage/Handling
Store at -20℃. Avoid freeze / thaw cycles.

Storage Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Immunogen Information

Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 1-280 of human Beclin 1 (NP_003757.1).

Sequence
MEGSKTSNNS TMQVSFVCQR CSQPLKLDTS FKILDRVTIQ ELTAPLLTTA QAKPGETQEE ETNSGEEPFI ETPRQDGVSR RFIPPARMMS TESANSFTLI GEASDGGTME NLSRRLKVTG DLFDIMSGQT DVDHPLCEEC TDTLLDQLDT QLNVTENECQ NYKRCLEILE QMNEDDSEQL QMELKELALE EERLIQELED VEKNRKIVAE NLEKVQAEAE RLDQEEAQYQ REYSEFKRQQ LELDDELKSV ENQMRYAQTQ LDKLKKTNVF NATFHIWHSG

Gene ID: 8678

Swiss Protein: Q14457

Calculated MW: 51 kDa

Observed MW: 60 kDa

Product Specifications

Catalog ID AB0918
Name Beclin 1 Polyclonal Antibody
Reactivity Human, Mouse, Rat
Tested Applications WB, IHC, IF, IP
Recommended Dilution • WB 1:500 - 1:2000
• IHC 1:50 - 1:200
• IF 1:50 - 1:200
• IP 1:50 - 1:100
Storage Buffer PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Positive Samples U-87MG, HeLa, MCF7, Mouse spleen, Rat ovary, Rat lung
Cellular Location Cytoplasm, Cytoplasmic vesicle, Endoplasmic reticulum membrane, Endosome, Endosome membrane, Golgi apparatus, Mitochondrion, Mitochondrion membrane, Nucleus, Peripheral membrane protein, autophagosome, trans-Golgi network membrane

Add To Cart

Catalog Number:
{{ currentSelection && currentSelection.sku ? currentSelection.sku : '...' }}
CAS Number:
{{ casNumber && casNumber.value ? casNumber.value : '...' }}
Size:
Quantity:
On Sale:
${{ currentSelection.price }} ${{ currentSelection.sale_price }}
Shipping:
Next day shipping required.

Join our list to receive promos and articles.

Join Now