Product Description

The T4 Gp59 protein plays critical roles in the assembly of the phage replisome and its coordination with homologous recombination. Gp59 is a versatile mediator protein that loads the replicative DNA helicase, Gp41, onto replication forks and recombination intermediates that are generated during different stages of the T4 infection cycle in its host organism, Escherichia coli. In addition to helicase loading, Gp59 has been shown to perform a second function: polymerase blocking. Gp59 inhibits the DNA synthesis and exonuclease activities of the phage polymerase, Gp43, until the replisome is fully assembled. Gp59 is free from detectable nuclease activities.

Product Includes

  • T4 gp59 protein
  • 10X gp59 reaction buffer

Purity: ≥98% (assessed by SDS-PAGE with Coomassie blue staining)

Concentration: 2 μg/μl

Source: E. coli BL21 (DE3) strain expressing T4 gp59 gene

Storage/Handling: Store at -20°C.
Product may be shipped on blue ice.

Product Specifications

Catalog ID T-420
Name T4 gp59 Protein
Storage/Handling Store at -20°C.

Technical Documentation

P Protocol
O Other
C Certificate of Analysis
S Safety Data Sheet

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