ADAM10 Polyclonal Antibody

Product Description

Members of the ADAM family are cell surface proteins with a unique structure possessing both potential adhesion and protease domains. This gene encodes and ADAM family member that cleaves many proteins including TNF-alpha and E-cadherin. Alternate splicing results in multiple transcript variants encoding different proteins that may undergo similar processing.

Product Name
ADAM10 Polyclonal Antibody
ADAM10 Rabbit pAb
ADAM10; AD10; AD18; CD156c; CDw156; HsT18717; MADM; RAK; kuz

Host Species
Rabbit

Purification Method
Affinity purification

Isotype
IgG

Storage/Handling
Store at -20℃. Avoid freeze / thaw cycles.

Storage Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Immunogen Information

Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 214-500 of human ADAM10 (NP_001101.1).

Sequence
TTSAEKNTCQ LYIQTDHLFF KYYGTREAVI AQISSHVKAI DTIYQTTDFS GIRNISFMVK RIRINTTADE KDPTNPFRFP NIGVEKFLEL NSEQNHDDYC LAYVFTDRDF DDGVLGLAWV GAPSGSSGGI CEKSKLYSDG KKKSLNTGII TVQNYGSHVP PKVSHITFAH EVGHNFGSPH DSGTECTPGE SKNLGQKENG NYIMYARATS GDKLNNNKFS LCSIRNISQV LEKKRNNCFV ESGQPICGNG MVEQGEECDC GYSDQCKDEC CFDANQPEGR KCKLKPG

Gene ID: 102

Swiss Protein: O14672

Calculated MW: 49 kDa/84 kDa

Observed MW: 70 kDa/105 kDa

Product Specifications

Catalog ID AB0159
Name ADAM10 Polyclonal Antibody
Reactivity Human, Mouse, Rat
Tested Applications WB, IF
Recommended Dilution • WB 1:500 - 1:2000
• IF 1:50 - 1:200
Storage Buffer PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Positive Samples HT-1080, Raji, Jurkat, Mouse kidney, Mouse brain
Cellular Location Cell membrane, Endomembrane system, Single-pass type I membrane protein

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