BMP2 Polyclonal Antibody
Product Description
This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer, which plays a role in bone and cartilage development. Duplication of a regulatory region downstream of this gene causes a form of brachydactyly characterized by a malformed index finger and second toe in human patients.
Product Name
BMP2 Polyclonal Antibody
BMP2 Rabbit pAb
BDA2; BMP2A; BMP2
Host Species
Rabbit
Purification Method
Affinity purification
Isotype
IgG
Storage/Handling
Store at -20℃. Avoid freeze / thaw cycles.
Storage Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Immunogen Information
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 283-396 of human BMP2 (NP_001191.1).
Sequence
QAKHKQRKRL KSSCKRHPLY VDFSDVGWND WIVAPPGYHA FYCHGECPFP LADHLNSTNH AIVQTLVNSV NSKIPKACCV PTELSAISML YLDENEKVVL KNYQDMVVEG CGCR
Gene ID: 650
Swiss Protein: P12643
Calculated MW: 44 kDa
Observed MW: 45 kDa
Product Specifications
| Catalog ID | AB0966 |
|---|---|
| Name | BMP2 Polyclonal Antibody |
| Reactivity | Human, Mouse, Rat |
| Tested Applications | WB, IHC |
| Recommended Dilution |
• WB 1:500 - 1:2000 • IHC 1:50 - 1:100 |
| Storage Buffer | PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Positive Samples | HeLa, THP-1, PC-12 |
| Cellular Location | Secreted |
