Gold Biotechnology offers more than 200 unique antibiotic agents for use in a wide variety of cell culture, microbiology and molecular biology applications. Antibiotic agents are often clinically used to inhibit bacterial growth or kill bacteria as selection markers in agar or liquid media. The first commercially available antibiotics were developed in the 1930s, starting with the sulfonamides in 1932 and exploded later with the discovery of penicillin in 1942. Gold Biotechnology’s antibiotics cover 14 classes, including aminoglycosides, carbapenems, macrolides, penicillins, quinolones, sulfonamides and tetracyclines, as well as multiple generations of cephalosporin antibiotics.
Gold Biotechnology offers more than 200 unique antibiotic agents for use in a wide variety of cell culture, microbiology and molecular biology applications. Antibiotic agents are often clinically used to inhibit bacterial growth or kill bacteria as selection markers in agar or liquid media. The first commercially available antibiotics were developed in the 1930s, starting with the sulfonamides in 1932 and exploded later with the discovery of penicillin in 1942. Gold Biotechnology’s antibiotics cover 14 classes, including aminoglycosides, carbapenems, macrolides, penicillins, quinolones, sulfonamides and tetracyclines, as well as multiple generations of cephalosporin antibiotics.
Antibiotics and Selection tools allow you to selectively control which cells can be found in your cultures.
GoldBio’s broad range of cell selection tools, including hundreds of antibiotics, antifungals and anticancers, plant selection and screening agents allow you to select, control and maintain your cell cultures with confidence and ease, no matter what cells you may be studying.
Antibiotics and Selection tools allow you to selectively control which cells can be found in your cultures.
GoldBio’s broad range of cell selection tools, including hundreds of antibiotics, antifungals and anticancers, plant selection and screening agents allow you to select, control and maintain your cell cultures with confidence and ease, no matter what cells you may be studying.
Shop a variety of antibiotics with broad or narrow spectrums of activity for your research. Gold Biotechnology offers high-quality antibiotics for wide range of target microorganisms, such as bacteria, fungi, viruses, or parasites.
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Antibiotic resistant genes are frequently used as a marker in molecular biology to select cells with foreign gene insertions. The cells surviving antibiotic treatment are maintained and propagated for downstream research experiments. Another common use of antibiotics is to prevent and eliminate contaminants in cell culture.
Choose your antibiotics based on popular applications: cloning, cell culture, plant research, or cancer research.
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Antibiotics are chemical substances that inhibit cell growth or kill cells. Different antibiotics (such as ampicillins, bactenicin, chloramphenicol, or rapamycin) target cells by using different mechanisms of action. Gold Biotechnology offers high-quality antibiotics with several groups of mode of actions for your research purpose.
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Product Description
Blasticidin S is an aminoacylnucleoside antibiotic isolated from Streptomyces griseochromogenes. It shows high efficacy against both eukaryotic and prokaryotic cells. Aside from its antimicrobial properties, blasticidin has displayed antiviral, antitumor, and antifungal properties and has been used as a selection agent. It has been used to select for cells containing the bls, bsr, or BSD resistance gene as well as HEK293-T cells and HEK-D5 cells. Additionally, blasticidin is effective in preventing cell culture contamination and studying protein synthesis.
Blasticidin S functions by inhibiting peptide bond formation at the ribosome. It blocks hydrolysis of peptidyl-tRNA due to the large ribosomal subunit's increased affinity for tRNA.
Antibiotics are often used in clinical in vitro tests known as antimicrobial susceptibility tests or ASTs to determine their efficacy against certain bacterial species. They are tested against gram-negative and gram-positive bacteria using panels, discs, and MIC strips by medical microbiologists. ASTs decrease the risk of using an antibiotic against bacteria exhibiting resistance to it, and the results are used in clinical settings to determine which antibiotic(s) to prescribe for various infections.
Product Specifications
Blasticidin S HCl
Blasticidin S Hydrochloride
Formula: C17H26N8O5 HCl
MW: 458.9 g/mol
Storage/Handling: Store desiccated at -20°C.
PubChem Chemical ID 16760315
Product Specifications
Catalog ID | B-800 |
---|---|
CAS # | 3513-03-9 |
MW | 458.90 g/mol |
Storage/Handling | Store desiccated at -20°C. |
UN Number | 2811 |
Item Class | 6.1 |
Group Number | II |