Netilmicin Sulfate

Product Description

Netilmicin sulfate is an aminoglycoside antibiotic similar to gentamicin and a derivative of sisomicin. It targets gram-negative bacteria as well as some gram-positive bacteria. Additionally, netilmicin has been used to study aminoglycoside resistance and susceptibility of Pseudomonas aeruginosa and Pseudomonas pseudomallei. It can be detected using liquid chromatography.

Aminoglycoside antibiotics are composed of amino groups attached to glycosides. They bind the 30s ribosomal subunit, causing misreading of the mRNA sequence and inhibition of translocation. Consequently, protein synthesis is inhibited.

Antibiotics are often used in clinical in vitro tests known as antimicrobial susceptibility tests or ASTs to determine their efficacy against certain bacterial species. They are tested against gram-negative and gram-positive bacteria using panels, discs, and MIC strips by medical microbiologists. ASTs decrease the risk of using an antibiotic against bacteria exhibiting resistance to it, and the results are used in clinical settings to determine which antibiotic(s) to prescribe for various infections.

Product Specifications
Netilmicin Sulfate

MOLECULAR BIOLOGY GRADE

Formula: C21H41N5O7 ∙ 2.5 H2SO4

MW: 720.75 g/mol

Storage/Handling: Store desiccated at 2-8°C. This product is light sensitive and is hygroscopic.

PubChem Chem ID: 62115

Product Specifications

Catalog ID N-630
CAS # 56391-57-2
MW 720.75 g/mol
Grade MOLECULAR BIOLOGY GRADE

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