Aminocoumarins

Aminocoumarins are a specialized class of antibiotics known for their potent inhibition of bacterial DNA gyrase and topoisomerase IV, enzymes essential for DNA replication and transcription.

These compounds are primarily active against Gram-positive bacteria and are frequently used in both antimicrobial resistance studies and molecular biology research. GoldBio offers high-quality novobiocin sodium salt, a well-established aminocoumarin, trusted for applications like producing positively supercoiled plasmids and studying Hsp90 inhibition. Whether you're investigating DNA supercoiling mechanisms or screening new antimicrobials, GoldBio provides reliable, research-grade reagents backed by scientific integrity and fast, dependable service.

1 product

  • Novobiocin Sodium Salt

    Novobiocin Sodium Salt Novobiocin Sodium Salt
    Catalog ID Size Pricing
    N-451-10 10 g $600.00

    Show Product Details

    product description

    Novobiocin Sodium Salt is an aminocoumarin antibiotic targeting gram-positive bacteria. It is used as a tool to produce positively-supercoiled plasmid DNA and in heat shock protein studies as it is an inhibitor of Hsp90.

    Novobiocin functions as an competitive inhibitor of prokaryotic DNA gyrase and eukaryotic DNA topoisomerase II. By inhibition of these enzymes, novobiocin blocks DNA synthesis, ultimately causing cell death.

    Product Specifications

    Catalog ID: N-451
    CAS # : 1476-53-5
    MW : 634.60 g/mol
    Storage/handling : Store desiccated at -20°C.
    View
    Packs & Pricing
    Catalog ID Size Pricing
    N-451-10 10 g $600.00

    $600.00

Login

Forgot your password?

Don't have an account yet?
Create account