Miltefosine is a biologically active alkylphospholipid that inhibits protein kinase C and phosphatidylcholine synthesis. It has been shown to induce apoptosis of a variety of cancer cell lines. Additionally, miltefosine is used against leishmaniasis and metronidazole-resistant and -susceptible strains of Trichomonas vaginalis. It is studied for its potential use as an anticancer agent.

Praziquantel is an anthelmintic drug used against schistosomes and cestodes. It functions by increasing the tegmentum permeability to calcium ions. This induces paralytic muscle contraction and death. Praziquantel is more effective on adult parasites than young parasites. It suppresses glucose uptake and stimulates lactate release.

Praziquantel is used to study voltage-gated calcium channels.

Salinomycin is a coccidiostat ionophore antibiotic isolated from Streptomyces albus. It increases cation movement across cell membranes through exchange-diffusion, resulting in altered gradients due to a lack of control of ion permeability. This effect allows ions (K+, Na+, Ca+, Mg2+) to accumulate inside the cell, reaching toxic levels.

Salinomycin is a coccidiostat ionophore antibiotic isolated from Streptomyces albus. It increases cation movement across cell membranes through exchange-diffusion, resulting in altered gradients due to a lack of control of ion permeability. This effect allows ions (K+, Na+, Ca+, Mg2+) to accumulate inside the cell, reaching toxic levels. Salinomycin sodium is freely soluble in aqueous solution.