2'-C-Methylcytidine is a nucleoside analog with antiviral properties. It has shown be a potent replication inhibitor, in vivo, towards multiple RNA viruses including hepatitus C virus (HCV). 2'-C-Methylcytidine has been shown inhibit viral RNA polymerase, disrupting replicon formation and preventing viral proliferation. While 2'-C-Methycytidine is a strong antiviral, it has exhibited low oral bioavailability.