Fusidic acid is a fusidane antibiotic compound that exerts potent bacteriostatic effects toward gram positive bacteria. It is commonly implemented with bactericidal antibiotics such as rifampicin. Fusidic acid is an inhibitor of protein synthesis by disrupting amino acid transfer from tRNA to ribosomes.

Fusidic acid inhibits a GTPase called elongation factor G or translocase. Impeding translocase activity hidners movement of tRNA and mRNA through ribosomes. While predominant effects are bacteriostatic, higher concentrations will result in bacterial death.

Fusidic acid sodium is a bacteriostatic steroid antibiotic targeting gram-positive bacteria, especially those responsible for skin infections. It has been shown to inhibit nitric oxide lysis of islet cells, cytokine production, neutrophils, and T cells. It is highly water soluble.

Fusidic acid sodium inhibits protein synthesis in prokaryotes via suppression of elongation factor G.