Acycloguanosine is a guanosine analogue that is synthetically formed. It is markedly effective against the herpesvirus family, especially HSV (herpes simplex viruses) types one and two. Lab results have shown susceptibility to acycloguanosine which varies with the analogue’s concentration, respective to each virus.
Acycloguanosine functions as a HSV DNA polymerase inhibitor by integrating into the viral DNA, terminating polymerization. Integration occurs after being catalyzed by viral thymidine kinase into acyclovir triphosphate (Acyclo-GTP). Acycloguanosine is ineffective against non-viral genetic material, due to the lack of an appropriate thymidine kinase.
MW: 225.20 g/mol
Storage/Handling: Store at room temperature.
PubChem Chemical ID: 2022
NOT FOR HUMAN USE!!