Cefmetazole free acid

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Description

Cefmetazole free acid is a second generation cephalosporin antibiotic that has a broad range of activity against gram-negative and gram-positive bacterium. Cefmetazole has exhibited great bactericidal activity against Staphylococcus aureus, which includes some methicillin-resistant strains.

Cephalosporins are a type of β-lactam antibiotic consisting of a four-membered β-lactam ring bound to a six-membered dihydrothiazine ring. This two-ring system causes distortion of the β-lactam amide bond, resulting in decreased resonance stabilization and increased reactivity. β-lactams inhibit the formation of peptidoglycan cross-links within bacterial cell walls by targeting penicillin-binding proteins or PBPs. Consequently, the bacterial cell wall becomes weak and cytolysis occurs. Cephalosporins are less susceptible to β-lactamases than the penicillin β-lactam antibiotics.


Product Specifications
Cefmetazole free acid

Formula: C15H17N7O5S3

MW: 471.53 g/mol

Storage/Handling: Store desiccated at -20°C.

PubChem Chemical ID: 42008

Cefmetazole free acid

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Catalog Number:
C-225-1
CAS Number:
56796-20-4
$105.00

For research use only. Not for food, drug, household, or cosmetic use.
Availability:
2-3 Weeks
Shipping:
$14.99 Ground shipping (In continental US only.)

    Description

    Cefmetazole free acid is a second generation cephalosporin antibiotic that has a broad range of activity against gram-negative and gram-positive bacterium. Cefmetazole has exhibited great bactericidal activity against Staphylococcus aureus, which includes some methicillin-resistant strains.

    Cephalosporins are a type of β-lactam antibiotic consisting of a four-membered β-lactam ring bound to a six-membered dihydrothiazine ring. This two-ring system causes distortion of the β-lactam amide bond, resulting in decreased resonance stabilization and increased reactivity. β-lactams inhibit the formation of peptidoglycan cross-links within bacterial cell walls by targeting penicillin-binding proteins or PBPs. Consequently, the bacterial cell wall becomes weak and cytolysis occurs. Cephalosporins are less susceptible to β-lactamases than the penicillin β-lactam antibiotics.


    Product Specifications
    Cefmetazole free acid

    Formula: C15H17N7O5S3

    MW: 471.53 g/mol

    Storage/Handling: Store desiccated at -20°C.

    PubChem Chemical ID: 42008

    Product Specifications

    Catalog ID: C-225
    CAS #: 56796-20-4
    MW: 471.53 g/mol
    Storage/handling: Store desiccated at -20°C.
    PubChem Chemical ID: 42008
    IUPAC Name: (6R,7S)-7-[[2-(cyanomethylsulfanyl)acetyl]amino]-7-methoxy-3-[(1-methyltetrazol-5-yl)sulfanylmethyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
    InChI: InChI=1S/C15H17N7O5S3/c1-21-14(18-19-20-21)30-6-8-5-29-13-15(27-2,17-9(23)7-28-4-3-16)12(26)22(13)10(8)11(24)25/h13H,4-7H2,1-2H3,(H,17,23)(H,24,25)/t13-,15+/m1/s1
    InChIKey: SNBUBQHDYVFSQF-HIFRSBDPSA-N
    SMILES: CN1C(=NN=N1)SCC2=C(N3C(C(C3=O)(NC(=O)CSCC#N)OC)SC2)C(=O)O

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