Description
Dirithromycin is a lipid soluble prodrug derivative of the macrolide antibiotic 9S-erythromycyclamine. It has a sizeable antibiotic activity range, being effective against gram positive and gram negative bacteria. It is highly insoluble in acidic and alkaline conditions and will spontaneously hydrolyze into the active erythromycyclamine form.
Macrolide antibiotics are composed of a macrocyclic lactone ring attached to one or more deoxy sugars. They inhibit bacterial protein synthesis by irreversibly binding the P site of the 50s ribosome, preventing peptide bond formation and translocation.
Product Specifications
Dirithromycin
Dirithromycine
Dirithromycinum
Formula: C42H78N2O14
MW: 835.07 g/mol
Storage/Handling: Store desiccated at room temperature.
PubChem Chemical ID: 6473883