Gatifloxacin

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Description

Gatifloxacin is a fourth generation fluoroquinolone antibiotic with a significant degree of activity towards gram-negative bacteria and enhanced activity toward gram-positive bacteria. It is also potent in vivo against Staphylococcus aureus, Clostridium and many other anaerobic bacteria. Gatifloxacin has also exhibited strong bactericidal efficiency in penicillin resistant and sensitive Streptococcus pneumoniae and S. aureus.

Fluoroquinolones are a group of broad-spectrum antibiotics that inhibit DNA synthesis. These antibiotics prevent unwinding of double-stranded DNA by binding DNA gyrase or DNA topoisomerase. By preventing the formation of single-stranded DNA, fluoroquinolones inhibit bacterial replication.


Product Specifications
Gatifloxacin
Gatifloxacin sesquihydrate

Formula: C19H22FN3O4 ∙ 1.5H2O

MW: 401.41 g/mol

Storage/Handling: Store at 4°C.

PubChem Chemical ID: 5379

Gatifloxacin

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Catalog Number:
G-410-1
CAS Number:
112811-59-3
$81.00

For research use only. Not for food, drug, household, or cosmetic use.
Availability:
2-3 Weeks
Shipping:
$14.99 Ground shipping (In continental US only.)

    Description

    Gatifloxacin is a fourth generation fluoroquinolone antibiotic with a significant degree of activity towards gram-negative bacteria and enhanced activity toward gram-positive bacteria. It is also potent in vivo against Staphylococcus aureus, Clostridium and many other anaerobic bacteria. Gatifloxacin has also exhibited strong bactericidal efficiency in penicillin resistant and sensitive Streptococcus pneumoniae and S. aureus.

    Fluoroquinolones are a group of broad-spectrum antibiotics that inhibit DNA synthesis. These antibiotics prevent unwinding of double-stranded DNA by binding DNA gyrase or DNA topoisomerase. By preventing the formation of single-stranded DNA, fluoroquinolones inhibit bacterial replication.


    Product Specifications
    Gatifloxacin
    Gatifloxacin sesquihydrate

    Formula: C19H22FN3O4 ∙ 1.5H2O

    MW: 401.41 g/mol

    Storage/Handling: Store at 4°C.

    PubChem Chemical ID: 5379

    Product Specifications

    Catalog ID: G-410
    CAS #: 112811-59-3
    Formula: C19H22FN3O4∙1.5H2O
    MW: 401.41 g/mol
    Storage/handling: Store desiccated at -20°C.
    PubChem Chemical ID: 5379
    IUPAC Name: 1-cyclopropyl-6-fluoro-8-methoxy-7-(3-methylpiperazin-1-yl)-4-oxoquinoline-3-carboxylic acid
    InChI: InChI=1S/C19H22FN3O4/c1-10-8-22(6-5-21-10)16-14(20)7-12-15(18(16)27-2)23(11-3-4-11)9-13(17(12)24)19(25)26/h7,9-11,21H,3-6,8H2,1-2H3,(H,25,26)
    InChIKey: XUBOMFCQGDBHNK-UHFFFAOYSA-N
    SMILES: CC1CN(CCN1)C2=C(C=C3C(=C2OC)N(C=C(C3=O)C(=O)O)C4CC4)F

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