4-Methylumbelliferyl a-L-idopyranosiduronic acid sodium salt

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Description

4-Methylumbelliferyl alpha-L-idopyranosiduronic acid sodium salt is a carbohydrate acid and organic sodium salt applied as an indicator. It is the fluorogenic substrate used in assays of α-L-Iduronidase and iduronate-2-sulfatase for identifying Hurler syndrome, also called mucopolysaccharidosis type I (MPS I). The disorder is characterized by α -L iduronidase enzyme deficiency, resulting in the buildup of glucosaminoglycans. Tests measure the chemical products 4-MU-α-IdoA or fluorophate 4-MU emitted following the enzymatic action of 4-Methylumbelliferyl alpha-L-idopyranosiduronic acid sodium salt. The substance is a white crystalline powder and is soluble in ethanol, methanol and water.

Product Specifications
4-Methylumbelliferyl alpha-L-idopyranosiduronic acid sodium salt
4-Methylumbelliferyl a-L-iduronicacid sodium salt
Sodium 4-methyl-2-oxo-2H-chromen-7-yl α-L-idopyranosiduronate
Sodium(4-methylumbelliferyla-L-idopyranosid)urinate

Formula: C16H15NaO9

MW: 374.27 g/mol

Storage/Handling: Store desiccated at -20°C.

PubChem Chemical ID: 71307170

4-Methylumbelliferyl a-L-idopyranosiduronic acid sodium salt

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Catalog Number:
M-490-10
CAS Number:
89157-94-8
$2,392.00

For research use only. Not for food, drug, household, or cosmetic use.
Availability:
2-3 Weeks
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    Description

    4-Methylumbelliferyl alpha-L-idopyranosiduronic acid sodium salt is a carbohydrate acid and organic sodium salt applied as an indicator. It is the fluorogenic substrate used in assays of α-L-Iduronidase and iduronate-2-sulfatase for identifying Hurler syndrome, also called mucopolysaccharidosis type I (MPS I). The disorder is characterized by α -L iduronidase enzyme deficiency, resulting in the buildup of glucosaminoglycans. Tests measure the chemical products 4-MU-α-IdoA or fluorophate 4-MU emitted following the enzymatic action of 4-Methylumbelliferyl alpha-L-idopyranosiduronic acid sodium salt. The substance is a white crystalline powder and is soluble in ethanol, methanol and water.

    Product Specifications
    4-Methylumbelliferyl alpha-L-idopyranosiduronic acid sodium salt
    4-Methylumbelliferyl a-L-iduronicacid sodium salt
    Sodium 4-methyl-2-oxo-2H-chromen-7-yl α-L-idopyranosiduronate
    Sodium(4-methylumbelliferyla-L-idopyranosid)urinate

    Formula: C16H15NaO9

    MW: 374.27 g/mol

    Storage/Handling: Store desiccated at -20°C.

    PubChem Chemical ID: 71307170

    Product Specifications

    Catalog ID: M-490
    CAS #: 89157-94-8
    Formula: C16H15NaO9
    MW: 374.27 g/mol
    Storage/handling: Store desiccated at -20°C.
    PubChem Chemical ID: 127239644
    IUPAC Name: sodium (3S,4S,6S)-3,4,5-trihydroxy-6-(4-methyl-2-oxochromen-7-yl)oxyoxane-2-carboxylate
    InChI: InChI=1S/C16H16O9.Na/c1-6-4-10(17)24-9-5-7(2-3-8(6)9)23-16-13(20)11(18)12(19)14(25-16)15(21)22;/h2-5,11-14,16,18-20H,1H3,(H,21,22);/q;+1/p-1/t11-,12-,13?,14?,16+;/m0./s1
    InChIKey: DJVQUWOKCARXPZ-JAKBELDKSA-M
    SMILES: CC1=CC(=O)OC2=C1C=CC(=C2)OC3C(C(C(C(O3)C(=O)[O-])O)O)O.[Na+]

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