Actinomycin D, USP Grade
Actinomycin D is an antineoplastic antibiotic from Streptomyces species that inhibits cell proliferation by acting as a cytotoxic inducer of apoptosis against tumor cells, binding to DNA and inhibiting RNA polymerase activity. Actinomycin is also used in plant tissue culture to inhibit plant growth through tissue deformation where it also acts as an RNA-synthesis inhibitor. Along with its fluorescent derivative, 7aminoactinomycinD (7-AAD), Actinomycin is used to stain GC-rich regions of DNA for microscopy and flow cytometry applications.
MW: 1255.41 g/mol
Storage/Handling: Store at -20°C.
PubChem Chemical ID: 457193