Gold Biotechnology offers more than 200 unique antibiotic agents for use in a wide variety of cell culture, microbiology and molecular biology applications. Antibiotic agents are often clinically used to inhibit bacterial growth or kill bacteria as selection markers in agar or liquid media. The first commercially available antibiotics were developed in the 1930s, starting with the sulfonamides in 1932 and exploded later with the discovery of penicillin in 1942. Gold Biotechnology’s antibiotics cover 14 classes, including aminoglycosides, carbapenems, macrolides, penicillins, quinolones, sulfonamides and tetracyclines, as well as multiple generations of cephalosporin antibiotics.
Gold Biotechnology offers more than 200 unique antibiotic agents for use in a wide variety of cell culture, microbiology and molecular biology applications. Antibiotic agents are often clinically used to inhibit bacterial growth or kill bacteria as selection markers in agar or liquid media. The first commercially available antibiotics were developed in the 1930s, starting with the sulfonamides in 1932 and exploded later with the discovery of penicillin in 1942. Gold Biotechnology’s antibiotics cover 14 classes, including aminoglycosides, carbapenems, macrolides, penicillins, quinolones, sulfonamides and tetracyclines, as well as multiple generations of cephalosporin antibiotics.
Antibiotics and Selection tools allow you to selectively control which cells can be found in your cultures.
GoldBio’s broad range of cell selection tools, including hundreds of antibiotics, antifungals and anticancers, plant selection and screening agents allow you to select, control and maintain your cell cultures with confidence and ease, no matter what cells you may be studying.
Antibiotics and Selection tools allow you to selectively control which cells can be found in your cultures.
GoldBio’s broad range of cell selection tools, including hundreds of antibiotics, antifungals and anticancers, plant selection and screening agents allow you to select, control and maintain your cell cultures with confidence and ease, no matter what cells you may be studying.
Shop a variety of antibiotics with broad or narrow spectrums of activity for your research. Gold Biotechnology offers high-quality antibiotics for wide range of target microorganisms, such as bacteria, fungi, viruses, or parasites.
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Antibiotic resistant genes are frequently used as a marker in molecular biology to select cells with foreign gene insertions. The cells surviving antibiotic treatment are maintained and propagated for downstream research experiments. Another common use of antibiotics is to prevent and eliminate contaminants in cell culture.
Choose your antibiotics based on popular applications: cloning, cell culture, plant research, or cancer research.
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Antibiotics are chemical substances that inhibit cell growth or kill cells. Different antibiotics (such as ampicillins, bactenicin, chloramphenicol, or rapamycin) target cells by using different mechanisms of action. Gold Biotechnology offers high-quality antibiotics with several groups of mode of actions for your research purpose.
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Product Description
Tetracycline is a broad-spectrum antibiotic targeting gram-negative and gram-positive bacteria. It also displays toxicity against certain eukaryotic cells. Tetracycline is used in multidrug resistance studies and in cell culture applications as a selective agent. Additionally, it promotes expression of the P450 proteins.
Tetracyclines are antibiotics made up of a four-ring system. They bind the 30s ribosomal subunit, preventing the aminoacyl-tRNA from attaching to the A site. Consequently, protein synthesis is inhibited. Resistance to tetracycline arises from loss of cell wall permeability and the tetR gene.
Antibiotics are often used in clinical in vitro tests known as antimicrobial susceptibility tests or ASTs to determine their efficacy against certain bacterial species. They are tested against gram-negative and gram-positive bacteria using panels, discs, and MIC strips by medical microbiologists. ASTs decrease the risk of using an antibiotic against bacteria exhibiting resistance to it, and the results are used in clinical settings to determine which antibiotic(s) to prescribe for various infections.
TESTED AGAINST BOTH SENSITIVE AND RESISTANT CELLS.
Product Specifications
Tetracycline Hydrochloride
MOLECULAR BIOLOGY GRADE
Formula: C 22H24N2O8HCl
MW: 480.9 g/mol
Storage/Handling: Store desiccated at -20°C, and protect from light. Soluble in water.
PubChem Chemical ID: 5359252
Product Specifications
Catalog ID | T-101 |
---|---|
CAS # | 64-75-5 |
MW | 480.90 g/mol |
Grade | MOLECULAR BIOLOGY GRADE |
Storage/Handling | Store desiccated at -20°C. Protect from light. |