Vancomycin Hydrochloride, USP Grade
Vancomycin hydrochloride is a member of the glycopeptide antibiotic class derived from Streptomyces orientalis. It is effective against gram-positive bacteria and used in studies of antibiotic resistance bacteria and nanoparticle transport studies. Exhibiting low toxicity to plants, vancomycin is suitable for plant selection and prevention of bacterial contamination in plant cell culture applications.
Vancomycin functions by inhibiting bacterial cell wall synthesis. It prevents transfer and addition of muramylpentapeptides that make up the peptidoglycan cell wall. It may be combined with cefotaxime or carbenicillin to display a synergistic effect against Agrobacterium species.
Antibiotics are often used in clinical in vitro tests known as antimicrobial susceptibility tests or ASTs to determine their efficacy against certain bacterial species. They are tested against gram-negative and gram-positive bacteria using panels, discs, and MIC strips by medical microbiologists. ASTs decrease the risk of using an antibiotic against bacteria exhibiting resistance to it, and the results are used in clinical settings to determine which antibiotic(s) to prescribe for various infections.
TESTED AGAINST BOTH SENSITIVE AND RESISTANT CELLS AT GOLD BIOTECHNOLOGY LAB.
Formula: C 66H75Cl2N9O24 HCl
MW: 1485.71 g/mol
Storage/Handling: Store desiccated at -20°C. Soluble in water.
Potency of greater than 1000 µg/mg
PubChem Chemical ID: 14970
|Storage/Handling||Store desiccated at -20°C.|
A brief explanation of the disk diffusion assay method used to test Gold Bio antibiotics
Examine the Effect of Carbenicilln, Cefotaxime and Vancomycin on Plant Morphogenesis by Teixeira da Silva, JA and S. Fukai (2001)