Cefotaxime (Sodium) 100 mg/mL Solution

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Description

GoldBio's Cefotaxime (Sodium) Solution is supplied as a ready-to-use 100 mg/mL solution, saving you preparation time by eliminating the need to weigh, dissolve, and filter sterilize antibiotic powder.

Providing a standardized concentration helps improve consistency between experiments while reducing preparation errors and the risk of contamination. The concentrated solution can be diluted to the desired working concentration, making it a convenient choice for routine microbiology, molecular biology, and plant research applications.

Cefotaxime is a third generation, broad-spectrum cephalosporin antibiotic effective against various gram-negative and gram-positive bacteria. However, unlike many other cephalosporins, cefotaxime is not effective against Pseudomonas aeruginosa bacteria. Cefotaxime is often used in Agrobacterium tumefaciens-mediated transformations to regulate bacterial growth. It has been shown to exhibit a synergistic effect with Vancomycin in certain conditions.

Cephalosporins are a type of β-lactam antibiotic consisting of a four-membered β-lactam ring bound to a six-membered dihydrothiazine ring. This two-ring system causes distortion of the β-lactam amide bond, resulting in decreased resonance stabilization and increased reactivity. β-lactams inhibit the formation of peptidoglycan cross-links within bacterial cell walls by targeting penicillin-binding proteins or PBPs. Consequently, the bacterial cell wall becomes weak and cytolysis occurs. Cephalosporins are less susceptible to β-lactamases than the penicillin β-lactam antibiotics.

GoldBio’s antibiotic solutions are provided ready to use.


Product Specifications:
Cefotaxime Sodium in H2O
(100 mg/mL Premade Solution, 0.2 µm Sterile Filtered)

MOLECULAR BIOLOGY GRADE

Formula: NaC16H16N5O7S2

MW: 477.45 g/mol

Storage/Handling: Store at -20°C.

PubChem Chemical ID: 10695961

Cefotaxime (Sodium) 100 mg/mL Solution

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Catalog Number:
C-104-SL10
CAS Number:
64485-93-4
$69.00 $62.00

For research use only. Not for food, drug, household, or cosmetic use.
Availability:
In stock
Shipping:
$59 Next Day Air + $15 Blue Ice

    Description

    GoldBio's Cefotaxime (Sodium) Solution is supplied as a ready-to-use 100 mg/mL solution, saving you preparation time by eliminating the need to weigh, dissolve, and filter sterilize antibiotic powder.

    Providing a standardized concentration helps improve consistency between experiments while reducing preparation errors and the risk of contamination. The concentrated solution can be diluted to the desired working concentration, making it a convenient choice for routine microbiology, molecular biology, and plant research applications.

    Cefotaxime is a third generation, broad-spectrum cephalosporin antibiotic effective against various gram-negative and gram-positive bacteria. However, unlike many other cephalosporins, cefotaxime is not effective against Pseudomonas aeruginosa bacteria. Cefotaxime is often used in Agrobacterium tumefaciens-mediated transformations to regulate bacterial growth. It has been shown to exhibit a synergistic effect with Vancomycin in certain conditions.

    Cephalosporins are a type of β-lactam antibiotic consisting of a four-membered β-lactam ring bound to a six-membered dihydrothiazine ring. This two-ring system causes distortion of the β-lactam amide bond, resulting in decreased resonance stabilization and increased reactivity. β-lactams inhibit the formation of peptidoglycan cross-links within bacterial cell walls by targeting penicillin-binding proteins or PBPs. Consequently, the bacterial cell wall becomes weak and cytolysis occurs. Cephalosporins are less susceptible to β-lactamases than the penicillin β-lactam antibiotics.

    GoldBio’s antibiotic solutions are provided ready to use.


    Product Specifications:
    Cefotaxime Sodium in H2O
    (100 mg/mL Premade Solution, 0.2 µm Sterile Filtered)

    MOLECULAR BIOLOGY GRADE

    Formula: NaC16H16N5O7S2

    MW: 477.45 g/mol

    Storage/Handling: Store at -20°C.

    PubChem Chemical ID: 10695961

    Product Specifications

    Catalog ID: C-104-SL
    CAS #: 64485-93-4
    Formula: NaC16H16N5O7S2
    MW: 477.45 g/mol
    Grade: MOLECULAR BIOLOGY GRADE
    Storage/handling: Store at -20°C.
    PubChem Chemical ID: 10695961
    IUPAC Name: sodium (6R,7R)-3-(acetyloxymethyl)-7-[[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-methoxyiminoacetyl]amino]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate
    InChI: InChI=1S/C16H17N5O7S2.Na/c1-6(22)28-3-7-4-29-14-10(13(24)21(14)11(7)15(25)26)19-12(23)9(20-27-2)8-5-30-16(17)18-8;/h5,10,14H,3-4H2,1-2H3,(H2,17,18)(H,19,23)(H,25,26);/q;+1/p-1/b20-9-;/t10-,14-;/m1./s1
    InChIKey: AZZMGZXNTDTSME-JUZDKLSSSA-M
    SMILES: CC(=O)OCC1=C(N2C(C(C2=O)NC(=O)C(=NOC)C3=CSC(=N3)N)SC1)C(=O)[O-].[Na+]

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