CSF2 (GM-CSF), Human

Product Description

GoldBio growth factors are manufactured for RESEARCH USE ONLY and cannot be sold for human consumption!

Recombinant Human Colony Stimulating Factor 2 (granulocyte-macrophage)
CSF2
GM-CSF
GMCSF
Molgramostin
MGI-1GM (Macrophage granulocyte inducer-1GM)

Colony Stimulating Factor 2 (GM-CSF) was initially characterized as a growth factor that can support the in vitro colony formation of granulocyte-macrophage progenitors. It is produced by a number of different cell types, including activated T cells, B cells, macrophages, mast cells, endothelial cells and fibroblasts, in response to cytokine or immune and inflammatory stimuli. CSF2 is also a growth factor for erythroid, megakaryocyte and eosinophil progenitors. On mature hematopoietic cells, CSF2 is a survival factor for and activates the effector functions of granulocytes, monocytes/macrophages and eosinophils. It can induce human endothelial cells to migrate and proliferate and can also stimulate the proliferation of a number of tumor cell lines, including osteogenic sarcoma, carcinoma and adenocarcinoma cell lines. CSF2 is species specific and human CSF2 has no biological effects on mouse cells.

Sterile Filtered White lyophilized powder. Purified and tested for use in cell culture.

Source: Escherichia coli

MW: ~14.6 kDa (128 amino acid)

Purity: >96% by SDS-PAGE and HPLC analyses

Storage/Handling: Store desiccated at -20°C.

HGNC ID: 2434

NOT FOR HUMAN USE!

Cross-species homology


Percent Similarity

HuCSF2 MuCSF2 RtCSF2
HuCSF2 *** 54.7 63.3
MuCSF2 *** *** 69.5
RtCSF2 *** *** ***

Additional resources for this protein may be found at:
OMIM

Product Specifications

Catalog ID 1120-03
MW ~14.6 kDa
Storage/Handling Store desiccated at -20°C.

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