GoldBio growth factors are manufactured for RESEARCH USE ONLY and cannot be sold for human consumption!
Recombinant Murine Fibroblast Growth Factor 18
FGF18 is a member of the Fibroblast Growth Factor family of proteins. FGF18 has been shown in vitro to induce neurite outgrowth in PC12 cells. Studies of the similar proteins in mouse and chick suggest that this protein is a pleiotropic growth factor that stimulates proliferation in tissues such as the liver and small intestine. FGF18 acts as a trophic factor for elastic chondrocytes in vivo and articular chondrocytes cultured in vitro and plays an autocrine role in normal articular cartilage repair. FGF18 –/– mice have decreased expression of osteogenic markers and delayed long-bone ossification. FGF18 has been shown in vitro that this protein is able to induce neurite outgrowth in PC12 cells. It is most closely related to FGF8 and FGF17 (see additional information).
Sterile Filtered White lyophilized powder. Purified and tested for use in cell culture.
Source: Escherichia coli
MW: ~21.0 kDa (180 amino acid)
Purity: >95% by SDS-PAGE and HPLC analyses
Storage/Handling: Store desiccated at -20°C.
NOT FOR HUMAN USE!
MGI: 1277980Cross-species homology
Additional resources for this protein may be found at:
|Storage/Handling||Store desiccated at -20°C.|
Relative mitogenic activity of FGFs against FGF Receptors compared to FGF1 (aFGF).
MuFGF18 Product Description, Amino Acid Sequence, Reconstitution and Storage Conditions