Azithromycin is a broad-spectrum macrolide antibiotic similar in structure to erythromycin. It is effective against various gram-negative and gram-positive bacteria. It has also displayed efficacy against certain Mycoplasma species. Azithromycin also exhibits anti-inflammatory and immunosuppressive properties. Azithromycin dihydrate is slightly soluble in aqueous solution.
Macrolide antibiotics are composed of a macrocyclic lactone ring attached to one or more deoxy sugars. They inhibit bacterial protein synthesis by irreversibly binding the P site of the 50s ribosome, preventing peptide bond formation and translocation.
Antibiotics are often used in clinical in vitro tests known as antimicrobial susceptibility tests or ASTs to determine their efficacy against certain bacterial species. They are tested against gram-negative and gram-positive bacteria using panels, discs, and MIC strips by medical microbiologists. ASTs decrease the risk of using an antibiotic against bacteria exhibiting resistance to it, and the results are used in clinical settings to determine which antibiotic(s) to prescribe for various infections.
MOLECULAR BIOLOGY GRADE
Formula: C38H72N2O12 · 2H2O
MW: 785.01 g/mol
Storage/Handling: Store at 4°C.
PubChem Chemical ID: 3033819
|Grade||MOLECULAR BIOLOGY GRADE|
|Storage/Handling||Store at 4°C.|