Aztreonam

Request Lot Specific COA

View Current Lot COA

Citation Search Tool

Description

Aztreonam is a monobactam β-lactam antibiotic whose structure contains only a single ring. Its unique ring structure makes it resistant to β-lactamases. Aztreonam is effective against gram-negative bacteria and is an economical antibiotic commonly used in plant tissue culture applications and against P. aeruginosa.

β-lactams inhibit the formation of peptidoglycan cross-links within bacterial cell walls by targeting penicillin-binding proteins or PBPs. Consequently, the bacterial cell wall becomes weak and cytolysis occurs. Resistance to β-lactam antibiotics occurs in the presence of cells containing plasmid encoded extended spectrum β-lactamases or ESBLs.


Product Specifications
Aztreonam

MOLECULAR BIOLOGY GRADE

Formula: C13H17N5O8S2

MW: 435.43 g/mol

Storage/Handling: Store at 4°C.
Aztreonam is soluble in DMF and DMSO and is insoluble in water.

PubChem Chemical ID: 5742832

Aztreonam

View Sizes & Pricing

Catalog Number:
A-930-500
CAS Number:
78110-38-0
$76.00

For research use only. Not for food, drug, household, or cosmetic use.
Availability:
In stock
Shipping:
$14.99 Ground shipping (In continental US only.)

    Description

    Aztreonam is a monobactam β-lactam antibiotic whose structure contains only a single ring. Its unique ring structure makes it resistant to β-lactamases. Aztreonam is effective against gram-negative bacteria and is an economical antibiotic commonly used in plant tissue culture applications and against P. aeruginosa.

    β-lactams inhibit the formation of peptidoglycan cross-links within bacterial cell walls by targeting penicillin-binding proteins or PBPs. Consequently, the bacterial cell wall becomes weak and cytolysis occurs. Resistance to β-lactam antibiotics occurs in the presence of cells containing plasmid encoded extended spectrum β-lactamases or ESBLs.


    Product Specifications
    Aztreonam

    MOLECULAR BIOLOGY GRADE

    Formula: C13H17N5O8S2

    MW: 435.43 g/mol

    Storage/Handling: Store at 4°C.
    Aztreonam is soluble in DMF and DMSO and is insoluble in water.

    PubChem Chemical ID: 5742832

    Product Specifications

    Catalog ID: A-930
    CAS #: 78110-38-0
    MW: 435.43 g/mol
    Grade: MOLECULAR BIOLOGY GRADE
    Storage/handling: Store at 4°C.
    PubChem Chemical ID: 5742832
    IUPAC Name: 2-[(Z)-[1-(2-amino-1,3-thiazol-4-yl)-2-[[(2S,3S)-2-methyl-4-oxo-1-sulfoazetidin-3-yl]amino]-2-oxoethylidene]amino]oxy-2-methylpropanoic acid
    InChI: InChI=1S/C13H17N5O8S2/c1-5-7(10(20)18(5)28(23,24)25)16-9(19)8(6-4-27-12(14)15-6)17-26-13(2,3)11(21)22/h4-5,7H,1-3H3,(H2,14,15)(H,16,19)(H,21,22)(H,23,24,25)/b17-8-/t5-,7-/m0/s1
    InChIKey: WZPBZJONDBGPKJ-VEHQQRBSSA-N
    SMILES: CC1C(C(=O)N1S(=O)(=O)O)NC(=O)C(=NOC(C)(C)C(=O)O)C2=CSC(=N2)N

    Featured Articles

      Login

      Forgot your password?

      Don't have an account yet?
      Create account