Description
Cefixime trihydrate is a broad-spectrum third generation cephalosporin targeting a wide range of gram-positive and gram-negative organisms. It is also used to detect ytterbium in mineral probes.
Cephalosporins are a type of β-lactam antibiotic consisting of a four-membered β-lactam ring bound to a six-membered dihydrothiazine ring. This two-ring system causes distortion of the β-lactam amide bond, resulting in decreased resonance stabilization and increased reactivity. β-lactams inhibit the formation of peptidoglycan cross-links within bacterial cell walls by targeting penicillin-binding proteins or PBPs. Consequently, the bacterial cell wall becomes weak and cytolysis occurs. Cephalosporins are less susceptible to β-lactamases than the penicillin β-lactam antibiotics.
Product Specifications
Cefixime Trihydrate
MOLECULAR BIOLOGY GRADE
Formula: C16H15N5O7S2 ∙ 3H2O
MW: 507.50 g/mol
Storage/Handling: Store desiccated at 4°C. Protect from light and air. Store under inert gas.
PubChem Chemical ID: 5362065
