Cefuroxime Sodium

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Description

Cefuroxime is a second generation cephalosporin antibiotic targeting gram-positive and gram-negative bacteria. It exhibits some resistance to β-lactamase activity. Cefuroxime sodium is freely soluble in aqueous solution.

Cephalosporins are a type of β-lactam antibiotic consisting of a four-membered β-lactam ring bound to a six-membered dihydrothiazine ring. This two-ring system causes distortion of the β-lactam amide bond, resulting in decreased resonance stabilization and increased reactivity. β-lactams inhibit the formation of peptidoglycan cross-links within bacterial cell walls by targeting penicillin-binding proteins or PBPs. Consequently, the bacterial cell wall becomes weak and cytolysis occurs. Cephalosporins are less susceptible to β-lactamases than the penicillin β-lactam antibiotics.


Product Specifications
Cefuroxime Sodium

MOLECULAR BIOLOGY GRADE

Formula: C16H15N4NaO8S

MW: 446.37 g/mol

Storage/Handling: Store at 2-8°C.

PubChem Chemical ID: 23670318

Cefuroxime Sodium

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Catalog Number:
C-790-1
CAS Number:
56238-63-2
$131.00

For research use only. Not for food, drug, household, or cosmetic use.
Availability:
In stock
Shipping:
$14.99 Ground shipping (In continental US only.)

    Description

    Cefuroxime is a second generation cephalosporin antibiotic targeting gram-positive and gram-negative bacteria. It exhibits some resistance to β-lactamase activity. Cefuroxime sodium is freely soluble in aqueous solution.

    Cephalosporins are a type of β-lactam antibiotic consisting of a four-membered β-lactam ring bound to a six-membered dihydrothiazine ring. This two-ring system causes distortion of the β-lactam amide bond, resulting in decreased resonance stabilization and increased reactivity. β-lactams inhibit the formation of peptidoglycan cross-links within bacterial cell walls by targeting penicillin-binding proteins or PBPs. Consequently, the bacterial cell wall becomes weak and cytolysis occurs. Cephalosporins are less susceptible to β-lactamases than the penicillin β-lactam antibiotics.


    Product Specifications
    Cefuroxime Sodium

    MOLECULAR BIOLOGY GRADE

    Formula: C16H15N4NaO8S

    MW: 446.37 g/mol

    Storage/Handling: Store at 2-8°C.

    PubChem Chemical ID: 23670318

    Product Specifications

    Catalog ID: C-790
    CAS #: 56238-63-2
    MW: 446.37 g/mol
    Grade: MOLECULAR BIOLOGY GRADE
    Storage/handling: Store at 4°C.
    PubChem Chemical ID: 23670318
    IUPAC Name: sodium (6R,7R)-3-(carbamoyloxymethyl)-7-[[(2Z)-2-(furan-2-yl)-2-methoxyiminoacetyl]amino]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate
    InChI: InChI=1S/C16H16N4O8S.Na/c1-26-19-9(8-3-2-4-27-8)12(21)18-10-13(22)20-11(15(23)24)7(5-28-16(17)25)6-29-14(10)20;/h2-4,10,14H,5-6H2,1H3,(H2,17,25)(H,18,21)(H,23,24);/q;+1/p-1/b19-9-;/t10-,14-;/m1./s1
    InChIKey: URDOHUPGIOGTKV-JTBFTWTJSA-M
    SMILES: CON=C(C1=CC=CO1)C(=O)NC2C3N(C2=O)C(=C(CS3)COC(=O)N)C(=O)[O-].[Na+]

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